东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Eisuke Nakazawa's research lab focuses on the ethical and societal implications of emerging technologies, particularly in healthcare and robotics. The lab explores the integration of artificial intelligence and neurotechnology into medical practice, emphasizing ethical frameworks for moral enhancement, patient autonomy, and responsible innovation. It also investigates human-technology interaction, with a special emphasis on aging populations and the role of wearable devices in preventing solitary deaths. The lab advocates for culturally inclusive ethical guidelines that balance Western technological ideals with Eastern philosophical values.
Professor Toru Kizaki's research lab specializes in advanced manufacturing technologies with a focus on precision machining, thermal error compensation in machine tools, and the processing of hard-to-machine ceramics such as yttria-stabilized tetragonal zirconia polycrystal (Y-TZP). The lab develops innovative sensing and monitoring systems—such as wireless multi-point temperature sensors and LATSIS for 3D thermal mapping—to enable real-time thermal error prediction and compensation. It also pioneers laser-assisted machining techniques for biomedical and dental ceramics, aiming to improve accuracy, efficiency, and cost-effectiveness in fabrication. The lab integrates advanced signal processing, machine learning, and model order reduction to optimize sensor placement and condition monitoring in complex mechanical systems.
Professor Keitaro Yoshimoto's research lab specializes in the development of functional nucleic acids and biomolecular recognition systems, with a focus on aptamers, DNA-based sensors, and molecularly engineered surfaces. The lab explores the design of selective molecular probes—such as small molecules and aptamers—that can detect nucleobases, proteins, and growth factors with high sensitivity and specificity, often leveraging fluorescence signaling or surface-based detection techniques. Key research directions include the application of abasic sites in DNA for selective nucleobase recognition, the engineering of protein-resistant surfaces using phosphorylcholine- and PEG-based polymers, and the discovery of high-affinity aptamers for therapeutic and diagnostic targets like thrombin and vascular endothelial growth factors. The lab integrates advanced analytical methods such as surface plasmon resonance, atomic force microscopy, and capillary electrophoresis to study molecular interactions at the nanoscale.
Professor Chieko Kai's research lab focuses on viral pathogenesis and host-virus interactions, with a central emphasis on paramyxoviruses such as measles virus (MeV) and Nipah virus (NiV). The lab investigates viral entry mechanisms, immune evasion strategies, and the identification of novel host factors involved in viral replication and pathogenesis. A key research direction involves developing oncolytic virotherapy using recombinant measles viruses engineered to selectively target and destroy cancer cells, particularly in pancreatic, breast, and lung cancers. The lab also contributes to the development of novel antiviral vaccines and therapeutics through reverse genetics and preclinical animal models.
Professor Eri Amasawa's research lab focuses on sustainable materials and circular economy solutions, with a strong emphasis on life cycle assessment (LCA) to evaluate environmental impacts across product design, consumption models, and emerging technologies. The lab investigates bio-based and biodegradable polymers like PHBH, smart energy-harvesting windows, and sustainable fashion business models such as clothing rental platforms to reduce environmental footprints. A key focus is on integrating environmental performance with consumer behavior and technological innovation to support low-carbon, resource-efficient societies. The lab combines empirical research, including surveys and interviews, with quantitative LCA to inform policy and design for sustainability.
Professor Kanako Makito's research lab specializes in perioperative medicine and pharmacovigilance, with a focus on anesthetic techniques and their impact on surgical outcomes, particularly in cancer and chronic respiratory disease patients. The lab investigates the long-term effects of anesthetic agents—such as volatile anesthetics (desflurane, sevoflurane) and intravenous anesthetics—on cancer recurrence, survival, and postoperative complications. It also explores the safety profiles of neuropathic pain medications like mirogabalin and pregabalin in older adults, with an emphasis on fracture risk and adverse events. Using large-scale national claims databases in Japan, the lab conducts real-world evidence studies to inform clinical decision-making.
Professor Yoshitaka Takano's research lab focuses on the molecular mechanisms underlying fungal pathogenesis in plant pathogens, with a particular emphasis on signal transduction pathways, effector biology, and host–pathogen interactions. The lab investigates how pathogens like *Colletotrichum lagenarium* and *Magnaporthe oryzae* manipulate host immunity through conserved effectors and MAP kinase signaling, while also exploring how host plants counter these strategies through metabolic and immune regulation. Key research directions include the role of sugar transporters in antibacterial defense, the function of MAP kinases in appressorium formation and virulence, and the identification of core effectors that suppress plant immune responses. The lab integrates molecular genetics, cell biology, and functional genomics to uncover fundamental principles of plant–microbe interactions.
Professor Yuko Yokoyama's research lab specializes in electrochemical science and materials engineering, with a focus on fundamental electrochemistry in aqueous systems, particularly concentrated electrolytes and local pH dynamics near electrodes. The lab investigates electrochemical energy conversion devices such as aqueous batteries, exploring ways to expand the electrochemical window and improve performance through novel electrolyte design. Additional research directions include magnetic nanostructures, such as NiFe wires for spintronic applications, and advanced microfabrication techniques for functional materials like molten-solder droplet generation and superconducting thin films.
Professor Hiroshi Ueda's research lab specializes in molecular and translational pain research, focusing on the neurobiological mechanisms underlying neuropathic and chronic pain conditions such as fibromyalgia. The lab investigates epigenetic regulation in sensory neurons, particularly the role of transcription factors like NRSF in pain plasticity, and explores natural compounds—especially flavonoids like luteolin—for their anti-inflammatory and analgesic properties. A key direction involves developing preclinical models of chronic pain to evaluate novel therapeutics, including gabapentin and opioid tolerance mechanisms, with an emphasis on sex differences and central sensitization.
Professor Megumi Nakao's research lab specializes in medical image computing and computational modeling for clinical applications, with a focus on image-guided surgery, organ reconstruction from limited imaging data, and metal artifact reduction in CT. The lab develops advanced machine learning and geometric modeling techniques to address challenges in 3D image reconstruction, soft-tissue deformation simulation, and patient-specific surgical planning. Key research directions include deformable image registration, unsupervised learning for medical imaging, and real-time interactive visualization of dynamic anatomical structures.
Professor Satoshi Yamada's research lab specializes in astrobiology and high-energy astrophysics, focusing on active galactic nuclei (AGNs), X-ray winds, and the multiwavelength properties of ultraluminous and luminous infrared galaxies. The lab conducts systematic X-ray spectroscopic and SED (spectral energy distribution) analyses using advanced space telescopes such as NuSTAR, Swift, Chandra, and XMM-Newton to study obscured AGNs, clumpy torus models, and the role of circumnuclear dust and gas in galaxy evolution. A key focus is identifying and characterizing 'buried' AGNs—especially Compton-thick systems—through X-ray and infrared indicators like [O IV] and [Ne V] emission lines.
Professor Yu Shiratsuchi's research lab specializes in advanced functional materials, with a primary focus on interfacial magnetism, diffusion mechanisms in III-V semiconductors, and oxide-based spintronic devices. The lab investigates fundamental mechanisms of ion diffusion—particularly Zn, Be, and Cr in GaAs—using the kick-out and dissociative mechanisms, while also exploring perpendicular exchange bias in Pt/Co/α-Cr₂O₃ heterostructures. Their work combines in-situ characterization techniques such as soft-x-ray magnetic circular dichroism and atomic force microscopy to probe interfacial spin structures and atomic-scale dynamics.
Professor Kazuko Kaneda-Nakashima's research lab specializes in targeted alpha therapy (TAT) for cancer treatment, focusing on the development of radiolabeled compounds that selectively deliver alpha-emitting radionuclides to tumor cells. The lab investigates tumor-specific transporters such as LAT1 and fibroblast activation protein (FAP) as molecular targets, designing and optimizing novel radioligands like 211At-labeled α-methyl-l-tyrosine and FAPI derivatives for precise tumor imaging and therapy. Their work emphasizes improving tumor targeting, therapeutic efficacy, and safety through rational molecular design and in vitro/in vivo evaluation. The lab also explores the biological mechanisms of allergic inflammation, particularly the role of zinc as a novel mediator in IgE-dependent signaling in mast cells.
Professor Kenichi Todo's research lab specializes in cerebrovascular diseases, with a focus on the mechanisms, diagnosis, and treatment of ischemic stroke. The lab investigates arrhythmias such as premature atrial contractions as potential hidden triggers of cardioembolic stroke, explores the role of collateral circulation in stroke outcomes, and examines rare but significant causes of embolic stroke, including small pulmonary arteriovenous malformings. Their work bridges clinical neurology and experimental stroke models, aiming to improve early diagnosis and expand therapeutic options for stroke patients.
Professor Minori Goto's research lab specializes in spintronics and nanomagnetic devices, focusing on the manipulation and characterization of topological spin textures such as skyrmions and magnetic vortices. The lab explores electric and spin-current-driven control of magnetic states, including the development of ultra-low power skyrmion-based circuits and spin-torque devices. Key research directions include tunneling anisotropic magnetoresistance, spin bolometers for sub-GHz detection, and electrical detection of magnetic textures using advanced nanofabricated heterostructures. The lab combines advanced nanofabrication, cryogenic measurements, and theoretical modeling to advance next-generation spintronic technologies.
Professor Tomoaki Iwayama's research lab focuses on the cellular and molecular mechanisms underlying tissue fibrosis, mineralization, and stem cell biology in metabolic and periodontal diseases. The lab employs advanced imaging techniques, genetic lineage tracing, and single-cell analyses to investigate the origin and function of perivascular cells, matrix vesicles, and tissue-resident stem cells in adipose tissue and periodontal ligaments. A central theme is understanding how cellular transitions and extracellular matrix dynamics contribute to organ fibrosis and mineralized tissue formation.
Professor Akihide Hibara's research lab specializes in microfluidics and interfacial phenomena, focusing on the design and fabrication of micro- and nanofluidic devices for advanced chemical and physical analysis. The lab develops innovative surface engineering techniques—such as capillarity-driven liquid handling, hydrophobic-hydrophilic patterning, and nanopillar structures—to control multiphase flows and interfacial transport at microscale. Their work spans time-resolved fluorescence measurements, quasi-elastic light scattering for interfacial dynamics, and contactless surface tension measurements of micrometer-scale droplets, enabling precise investigation of mass transfer and reaction processes in confined environments. The lab's research bridges fundamental interfacial science with practical applications in chemical separations, distillation, and microchemical systems.
Professor Masato Takase's research lab specializes in epidemiological and clinical studies focusing on cardiovascular and metabolic disease risk factors in the Japanese population. The lab investigates the interplay between genetic predisposition, lifestyle factors, and physiological markers such as blood pressure, body composition, and arterial stiffness. Key research directions include the development of prediction models for respiratory and metabolic health, polygenic risk scores for hypertension, and the role of body composition and metabolic profiles in cardiovascular disease prevention.
Professor Kunihiko Nakai's research lab focuses on the neurodevelopmental and toxicological impacts of environmental pollutants, particularly methylmercury and persistent organic pollutants (POPs), in children. The lab conducts longitudinal birth cohort studies—such as the Tohoku Study of Child Development—to investigate the effects of prenatal and postnatal exposure to neurotoxicants on cognitive and motor development, with a special emphasis on sex-specific vulnerabilities. Research also extends to the biological mechanisms of hemoglobin-based oxygen carriers and their vasoconstrictive effects, linking hemoglobin chemistry to vascular function. The lab integrates epidemiology, environmental health, and clinical toxicology to assess risks associated with seafood consumption and environmental contaminants in high-fish-consuming populations like those in Japan.
Professor Liying Yao's research lab specializes in structural chemistry and crystallography, focusing on the determination and analysis of molecular structures through X-ray diffraction. The lab investigates the solid-state packing and intermolecular interactions in organic compounds, particularly emphasizing weak C—H⋯O interactions that influence crystal architecture. Their work often involves the study of molecular conformation and polymorphism, with applications in understanding structure-property relationships in functional organic materials. The lab actively contributes to the Cambridge Structural Database, advancing the global repository of small-molecule crystal structures.
