东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Masaki Kuwatani's research lab specializes in translational oncology and precision medicine for pancreatic cancer, focusing on improving treatment outcomes through advanced imaging, molecular diagnostics, and personalized therapeutic strategies. The lab investigates the utility of FDG-PET and tumor markers as adjuncts to CT for predicting chemotherapy response and survival, evaluates stent selection during neoadjuvant therapy to optimize patient outcomes, and develops innovative genetic analysis techniques using EUS-FNA samples to identify actionable genomic alterations. Their work bridges clinical imaging, interventional radiology, and molecular pathology to enhance early detection, treatment selection, and prognosis prediction in pancreatic ductal adenocarcinoma.
Professor Mamoru Oshiki's research lab specializes in the microbiology and biochemistry of anaerobic ammonium-oxidizing (anammox) bacteria, focusing on their physiology, metabolism, and ecological roles in nitrogen cycling. The lab investigates the diversity, phylogeny, and unique metabolic pathways of anammox bacteria such as 'Candidatus Brocadia sinica' and 'Candidatus Scalindua' species, particularly their ability to couple ammonium oxidation with nitrite or nitrate reduction. Using advanced molecular techniques, genome sequencing, and stable isotope tracer experiments, the lab explores novel metabolic routes, including nitrate-dependent iron oxidation and alternative nitrite reduction pathways, contributing to a deeper understanding of microbial nitrogen transformations in natural and engineered ecosystems.
Professor Masaki Yoshida's research lab specializes in the molecular design and mechanistic study of transition metal complexes for energy-relevant catalysis, particularly water oxidation and O–O bond formation. The lab focuses on developing efficient, selective, and robust molecular catalysts—especially ruthenium-based systems—by tuning ligand environments, secondary coordination spheres, and electronic properties. Key research directions include understanding the role of ligand architecture, electron-donating groups, and functionalized pendant groups (e.g., SO₃⁻) in enhancing catalytic activity and stability. The lab also explores redox-active metal complexes with unique electronic and optical properties, such as mixed-valent platinum dimers, for potential applications in molecular electronics and sensing.
Professor Keisuke Kamada's research lab specializes in clinical and molecular microbiology, with a primary focus on rapidly growing mycobacteria (RGM), particularly *Mycobacteroides abscessus* complex. The lab investigates antimicrobial resistance mechanisms, species-level characterization, and treatment strategies for difficult-to-treat mycobacterial infections, especially in respiratory and otological contexts. Their work integrates molecular diagnostics, antimicrobial susceptibility testing, and clinical case studies to improve patient outcomes in drug-resistant infections.
Professor Yu Fujimoto's research lab specializes in smart energy systems, with a focus on optimizing the integration of renewable energy sources—particularly photovoltaic and wind power—into distribution networks. The lab develops advanced energy management systems (EMS) that enable distributed energy resource coordination through forecasting, planning, and control under real-time pricing and grid constraints. Key research directions include demand response, battery energy storage system (BESS) planning for multipurpose utilization, and machine learning-based prediction for ramp events and load demand. The lab emphasizes practical deployment through edge computing and platform-based evaluation in real urban environments.
Professor Heming Sun's research lab specializes in energy-efficient and high-performance signal and image processing, with a strong focus on video and image compression technologies. The lab explores low-complexity algorithms, hardware-efficient architectures, and fixed-point quantization techniques for next-generation video coding standards such as HEVC and VVC, as well as learned image compression (LIC). Key research directions include complexity reduction in coding tools, approximation techniques for transform and prediction units, and model compression for deep learning-based image codecs to enable deployment on embedded and resource-constrained systems. The lab bridges theoretical algorithm design with practical VLSI implementation, emphasizing energy efficiency, area optimization, and robustness across platforms.
Professor Jialong Li's research lab specializes in self-adaptive systems (SAS), focusing on enhancing system resilience and autonomy through advanced techniques such as generative AI, large language models (LLMs), reinforcement learning, and formal methods. The lab explores innovative integration of AI and formal verification to enable real-time adaptation, requirement relaxation, and runtime model synthesis in dynamic environments. Key research directions include intelligent adaptation mechanisms, goal-oriented runtime monitoring, and efficient knowledge reuse in adaptive systems.
Professor Shin-ichi Sakakibara's research lab focuses on the molecular and cellular mechanisms underlying neural stem/progenitor cell regulation during embryonic and postnatal neurogenesis. The lab investigates RNA-binding proteins such as Musashi1 and Musashi2, which play critical roles in maintaining neural precursor cell identity and fate determination. Additionally, the lab explores posttranslational modifications, including SUMOylation, and cytoskeletal regulators like Radmis/CKAP2L, to understand their roles in neural development and homeostasis. The work often integrates genetic, molecular, and cellular approaches to dissect the intrinsic and extrinsic signals governing neural cell differentiation and function.
Professor Miguel Esteban's research lab specializes in coastal and ocean engineering, focusing on tsunami hazard assessment, typhoon-induced wave dynamics, and the resilience of coastal structures under extreme environmental conditions. The lab investigates the impacts of climate change on coastal hazards, particularly the combined effects of rising sea levels and intensified tropical cyclones on infrastructure stability. Using advanced numerical modeling and field surveys, the lab evaluates risks to breakwaters and coastal communities, aiming to improve predictive models and engineering designs for disaster mitigation.
Professor Takuya Kochi's research lab specializes in transition-metal-catalyzed organic synthesis, with a focus on developing innovative methods for selective C–C and C–heteroatom bond formation. Key research directions include chain-walking catalysis for functionalizing unreactive C–H bonds, asymmetric synthesis of chiral amines and amino alcohols using N-sulfinyl imine-derived metalloenamines, and regioselective C–H functionalization via ruthenium- and palladium-catalyzed reactions. The lab emphasizes the design of efficient, diastereoselective transformations with applications in natural product synthesis and the creation of structurally complex molecules.
Professor Takashi Kiuchi's research lab focuses on molecular genetics and genomics of lepidopteran insects, particularly the silkworm Bombyx mori, with key research directions in genome assembly and functional genomics, sex determination mechanisms involving piRNA and W chromosome factors, and the genetic and biochemical basis of pigmentation and diapause regulation. The lab employs advanced sequencing technologies, reverse genetics, and physiological assays to dissect complex biological processes such as uric acid-based coloration, photoperiodic diapause, and circadian clock involvement in seasonal adaptation. Their work bridges fundamental insect biology with applications in pest management and biotechnology.
Professor Hiroaki Matsui's research lab specializes in the epitaxial growth and fundamental characterization of wide-bandgap semiconducting oxides, with a focus on nitrogen doping and heteroepitaxial integration of complex oxide heterostructures. The lab employs advanced pulsed laser deposition and molecular beam epitaxy techniques to achieve precise control over crystal structure, doping, and nanostructure formation in materials such as ZnO, TiO2, and MgZnO. Key research directions include plasmonic properties in VO2-based 2D nanostructures, defect and dopant engineering for optoelectronic applications, and the development of high-quality oxide heteroepitaxial films for next-generation electronic and photonic devices. The lab emphasizes the correlation between growth conditions, atomic-scale structure, and functional properties through advanced in-situ and ex-situ characterization techniques.
Professor Shuji Shinohara's research lab specializes in the intersection of speech analysis, emotional state assessment, and mental health diagnostics. The lab develops novel voice-based biomarkers—such as vitality, arousal level indices (ALVI, EALVI), and pitch rate—to objectively measure emotional and psychological states, particularly in depression. Their work leverages naturalistic speech data from smartphones and motion-capture databases to create clinically relevant, non-invasive tools for early detection and monitoring of mood disorders. The lab emphasizes real-world applicability by evaluating these indices in free-form speech rather than controlled laboratory conditions.
Professor Satoshi Sawai's research lab specializes in the interdisciplinary study of collective cell dynamics, focusing on the emergence of complex spatiotemporal patterns in biological systems. The lab investigates mechanisms underlying cell migration, chemotaxis, and oscillatory behavior in systems such as Dictyostelium discoideum, integrating experimental imaging, quantitative image analysis, and computational modeling. A central theme is understanding how individual cell behaviors—such as reorientation, symmetry breaking, and rhythmic signaling—give rise to tissue-level coordination through principles like reaction-diffusion instabilities and feedback regulation. The lab also pioneers innovative approaches, including time-lapse video screening and deep learning-based morphological analysis, to decode gene-phenotype relationships in cell populations.
Professor Taro Toyota's research lab specializes in the design and fabrication of artificial cell-like systems based on giant vesicles and self-propelled droplets, focusing on autonomous dynamics, self-replication, and adaptive behaviors. The lab explores the integration of chemical energy transduction, in situ synthesis of membrane components, and stimuli-responsive materials to create dynamic, life-like systems. Key research directions include the self-reproduction of multilamellar vesicles, chemically driven self-propulsion in oil-in-water emulsions, and the development of functionalized vesicles for biomedical imaging and sensing applications.
Professor Sho Kano's research lab specializes in advanced structural materials for fusion energy applications, with a primary focus on ferritic/martensitic steels such as F82H. The lab investigates microstructural evolution, precipitation behavior, and irradiation resilience in these steels under extreme conditions typical of fusion reactor environments. Key research directions include the characterization of carbide and nitride precipitates using advanced electron microscopy and extraction techniques, as well as the mechanical property evaluation of weld joints and heat-affected zones in dissimilar metal joints. The lab also explores the effects of irradiation on precipitate stability and radiation-induced defects, aiming to enhance the performance and longevity of fusion reactor components.
Professor Tsuyohito Ito's research lab specializes in the fundamental physics and engineering of micro- and nanoscale plasmas, with a focus on ultrafast discharge dynamics, electric field diagnostics, and compact plasma sources. The lab investigates high-pressure and supercritical fluid plasmas, nanosecond-scale dielectric barrier discharges, and thermoelectron-enhanced microplasmas, aiming to enable low-voltage, stable, and efficient plasma generation. Key innovations include the development of coherent Raman scattering for real-time electric field imaging and the design of miniaturized plasma devices such as micro-Hall thrusters and capillary plasmas for space and industrial applications.
Professor Kimito Funatsu's research lab specializes in chemometrics, cheminformatics, and process systems engineering, with a strong focus on developing advanced data-driven methods for chemical process monitoring and molecular structure elucidation. The lab pioneers adaptive soft sensor technologies that enhance predictive accuracy in dynamic industrial environments, particularly through online learning algorithms like support vector regression and genetic algorithm-based variable selection. Their work also extends to automated structure elucidation using NMR spectroscopy, integrating multi-dimensional spectral data to improve reliability in molecular structure determination. The lab emphasizes robust modeling under changing process conditions and the quantitative assessment of model applicability domains to ensure real-time process control and quality prediction.
Professor Bo-Kyung Son's research lab focuses on vascular biology and cardiovascular disease mechanisms, with a central emphasis on vascular calcification, a key pathological process in atherosclerosis and aortopathy. The lab investigates molecular regulators such as Gas6, GM-CSF, adiponectin, and androgens, exploring their roles in vascular smooth muscle cell fate decisions, including apoptosis and osteogenic transformation. A major research direction involves identifying endogenous protective pathways and developing novel therapeutic strategies, including phage endolysins as alternatives to antibiotics. The lab integrates molecular and cellular biology with translational approaches to uncover targets for treating cardiovascular and infectious diseases.
Professor Ryota Masuki's research lab specializes in first-principles theoretical studies of quantum materials, with a focus on phonon anharmonicity, structural phase transitions, and thermodynamic properties at finite temperatures. The lab develops advanced computational frameworks—such as the self-consistent phonon (SCP) and quasiharmonic approximation (QHA) theories—to predict and understand complex behaviors like thermal expansion, pyroelectricity, and polar metal transitions. Their work uniquely integrates efficient interatomic force constant updates and variational free energy minimization to enable accurate, ab initio structural optimization under thermal effects. The lab also investigates transport phenomena, particularly the phonon-drag mechanism in narrow-gap semiconductors, linking microscopic electron-phonon interactions to macroscopic thermoelectric responses.
