东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Daniel Headland's research lab specializes in advancing terahertz technology through innovative photonic and electromagnetic design. The lab focuses on developing high-efficiency beam control techniques, integrated waveguide platforms, and reconfigurable metasurfaces for applications in terahertz communications, imaging, and sensing. Key research directions include metasurface-based lenses and reflectarrays, photonic crystal waveguides in high-resistivity silicon, and monolithic integration of terahertz components using advanced microfabrication techniques.
Professor Shih-Nan Hsiao's research lab specializes in advanced thin film materials and plasma-based nanofabrication, with a focus on controlling the microstructure, stress evolution, and magnetic properties of L10-ordered FePt films for high-density magnetic storage applications. The lab investigates rapid thermal annealing and stress engineering to manipulate crystallographic texture and phase transformation kinetics, while also exploring novel plasma etching processes—particularly at cryogenic temperatures—for sub-nanoscale patterning of dielectrics and nitrides. Their work bridges materials synthesis, in-situ stress monitoring, and plasma chemistry to enable next-generation semiconductor device fabrication.
Professor Hirokazu Kumazaki's research lab specializes in the application of humanoid and android robots in therapeutic interventions for individuals with autism spectrum disorder (ASD). The lab focuses on enhancing social communication skills, particularly nonverbal communication and self-disclosure, through robot-mediated training programs such as mock job interviews and conversational interaction. A central theme of the research is understanding how different robot appearances—ranging from simplistic humanoids to highly realistic androids—affect user engagement and preference among individuals with ASD. The lab also investigates the psychological and physiological impacts of robot-assisted therapy, including stress reduction and increased self-efficacy.
Professor Yuki Isobe's research lab specializes in observational astrophysics, focusing on the chemical evolution and physical conditions of high-redshift star-forming galaxies using cutting-edge space-based telescopes such as the James Webb Space Telescope (JWST). The lab investigates electron densities, metallicity, and abundance ratios—particularly C/N and N/O—in early galaxies to understand the processes of early star formation and chemical enrichment. A key focus is identifying signatures of active galactic nuclei and their role in nitrogen enrichment, as well as exploring the origins of extreme chemical compositions in the early universe. The lab also engages in the study of bioactive lipid mediators, such as resolvin E3, linking inflammation resolution to human health and disease.
Professor Julian Webber's research lab specializes in advanced photonic and wireless communication technologies, with a focus on terahertz-band systems, integrated photonics, and high-speed optical interconnects. The lab explores next-generation communication standards, including 6G wireless systems, by leveraging photonic frequency combs, topological photonics, and millimeter-wave signal generation for ultra-broadband applications. Research also extends to optimizing photovoltaic systems through statistical modeling and module sorting to minimize power loss. The lab bridges fundamental photonics with practical wireless communication solutions, targeting high data rate, low-latency, and energy-efficient systems.
Professor Ammarueda Issariyapat's research lab specializes in materials science with a focus on intermetallic phases, particularly aluminum-nickel systems, and their synthesis, microstructure evolution, and thermodynamic behavior under controlled processing conditions. The lab investigates diffusion-controlled reactions, phase transformations, and interfacial phenomena during electrodeposition and heat treatment, aiming to understand and tailor the formation of intermetallic compounds such as Ni2Al3 and NiAl3. Their work combines advanced characterization techniques like SEM, EDS, GIXD, and DTA to explore the kinetics and thermodynamics of solid-state reactions and localized melting in Al-Ni systems.
Professor Seungkyun Yim's research lab specializes in advanced additive manufacturing, with a focus on powder bed fusion processes such as laser and electron beam melting. The lab investigates fundamental mechanisms governing powder spreading, interfacial bonding, and defect formation under various conditions—including low gravity and complex surface topographies—using a combination of experimental studies, discrete element modeling (DEM), and machine learning. Key research directions include optimizing process parameters, particle size distribution, and spreading strategies to enhance part quality, density, and defect control in multi-material and dissimilar metal components.
Professor Kazuyoshi Kobayashi's research lab specializes in spinal surgery and geriatric orthopedics, focusing on improving surgical outcomes for elderly patients, particularly those aged 80 and older. The lab conducts large-scale, multicenter retrospective studies using clinical registries to analyze perioperative complications, surgical trends, and risk factors for falls in aging inpatients. Key research directions include optimizing surgical timing, minimizing invasiveness, and enhancing patient safety in the very elderly, with a strong emphasis on evidence-based clinical decision-making. The lab also investigates spinal meningioma management and long-term prognostic factors to guide optimal surgical resection strategies.
Professor Youhei Yamashita's research lab specializes in aquatic organic geochemistry, focusing on the sources, transformations, and environmental behavior of dissolved organic matter (DOM) in marine and estuarine systems. The lab employs advanced optical techniques—particularly excitation-emission matrix (EEM) fluorescence spectroscopy combined with parallel factor analysis (PARAFAC)—to characterize fluorescent components of DOM and their interactions with metals such as Cu(II) and Hg(II). Key research directions include understanding the origins and mixing dynamics of DOM in coastal environments, assessing the role of in situ production versus terrestrial inputs in shaping chromophoric DOM (CDOM) distributions, and evaluating the impact of photobleaching and biological degradation on CDOM spectral properties. The lab also investigates the biogeochemical significance of DOM in global oceanic cycles, particularly in tropical and marginal seas.
Professor Kazuo Terashima's research lab specializes in advanced materials science and agricultural biotechnology, with a focus on plasma-based materials synthesis and the physiological mechanisms underlying rice plant stability and yield. The lab investigates high-deposition-rate superconducting film fabrication using reactive plasma evaporation, as well as the physiological and genetic basis of lodging resistance in rice, particularly under extreme weather conditions. Their work bridges materials engineering and crop science, addressing challenges in both nanomaterial development and sustainable agriculture. The lab also explores plasma applications in biomedicine and environmental adaptation in crops.
Professor Tomoya Kinugawa's research lab specializes in theoretical astrophysics, focusing on the formation, evolution, and gravitational wave signatures of Population III stars and their remnants. The lab conducts detailed population synthesis simulations to explore the properties of binary black holes formed from massive, metal-free stars, with particular emphasis on their chirp masses, merger rates, and detectability by current and future gravitational wave observatories such as KAGRA, LIGO, and Virgo. A key research direction involves linking theoretical predictions of Pop III binary evolution to observed gravitational wave events like GW190521, aiming to constrain the early star formation history and initial mass functions of the first stars in the universe. The lab also develops empirical fitting formulae for massive star evolution under extreme metal-poor conditions to improve the accuracy of population synthesis models.
Professor Masashi Mizuguchi's research lab specializes in pediatric neurology and neuropathology, focusing on the mechanisms, clinical features, and molecular pathology of acute encephalopathies and neurodevelopmental disorders. The lab investigates rare and severe brain disorders such as acute necrotizing encephalopathy of childhood, tuberous sclerosis complex (TSC), and neuronal migration disorders like Miller-Dieker syndrome. Using both clinical case studies and animal models—such as the Eker rat model of TSC—the lab explores the genetic, histological, and immunohistochemical underpinnings of these conditions, with translational goals in improving diagnosis, treatment, and outcomes. The lab also evaluates novel therapeutic approaches, including mTOR inhibitors like everolimus, for refractory seizures and behavioral symptoms in TSC patients.
Professor Hitoshi Takane's research lab specializes in the epitaxial growth and fundamental characterization of wide and ultrawide bandgap semiconductors, with a focus on rutile-structured oxides such as GeO₂, Ga₂O₃, and SnO₂-based alloys. The lab employs advanced thin-film deposition techniques—particularly mist chemical vapor deposition (mist-CVD)—to develop high-quality, single-crystalline oxide films for next-generation power electronics and optoelectronic devices. Key research directions include defect engineering, threading dislocation analysis, and the development of heteroepitaxial systems with lattice-matched substrates to achieve high carrier mobility and low defect densities.
Professor Qian Wang's research lab specializes in advanced materials and sustainable manufacturing, focusing on catalytic degradation of plastic waste, particularly poly(ethylene terephthalate) (PET), using novel ionic liquids and green catalysts. The lab also conducts cutting-edge research in thermal-mechanical modeling of advanced manufacturing processes such as wire arc additive manufacturing (WAAM), with an emphasis on residual stress prediction and optimization. Additionally, the lab investigates advanced joining technologies for high-temperature electronic packaging using nanoscale silver pastes and surface engineering. These interdisciplinary efforts integrate materials chemistry, mechanical modeling, and sustainable processing for industrial applications.
Professor Masahiro Yamamoto's research lab focuses on innate immune signaling pathways, particularly the molecular mechanisms underlying Toll-like receptor (TLR)-mediated immune responses. The lab investigates key adaptor molecules such as MyD88, TRIF, and TIRAP in mediating inflammatory and type I interferon responses during microbial infections. A central theme is understanding how pathogens like *Toxoplasma gondii* manipulate host signaling pathways—especially the Stat3 pathway—through virulence factors such as ROP16 to evade immune surveillance. The lab combines molecular immunology, host-pathogen interactions, and reverse genetics to dissect the intricate signaling networks that govern host defense and immune evasion.
Professor Taisuke Nakahama's research lab focuses on the molecular mechanisms underlying immune system regulation, particularly the roles of RNA editing enzymes like ADAR1 and transcriptional regulators such as the aryl hydrocarbon receptor (AHR) in immune cell development and autoimmune diseases. The lab investigates how ADAR1 prevents innate immune activation by editing endogenous dsRNA to avoid MDA5-mediated type I interferon responses, and explores the distinct functions of its p110 and p150 isoforms in thymic development and central tolerance. Additionally, the lab examines how AHR and microRNAs such as the miR-132/212 cluster regulate T helper cell differentiation, especially Th17 and regulatory T cells, in the context of autoimmunity. These studies aim to uncover novel therapeutic targets for autoimmune and inflammatory disorders.
Professor Hiromu Tanimoto's research lab focuses on dissecting the neural circuits underlying learning, memory, and behavior in *Drosophila melanogaster*. The lab employs genetic tools, such as the GAL4/UAS system and intersectional techniques, to map and manipulate specific neurons, particularly dopamine and octopaminergic neurons, with single-cell resolution. Key research directions include understanding the functional diversity of mushroom body neurons, the role of neuromodulators in behavior, and the circuit mechanisms of reinforcement learning. The lab also develops and utilizes advanced genetic resources, such as receptor reporter libraries and cell-type-specific drivers, to decode neural circuit organization and function.
Professor Kazunobu Toshima's research lab specializes in synthetic organic chemistry, with a primary focus on the development of innovative glycosylation methodologies for the efficient synthesis of complex natural products. The lab is renowned for pioneering regio- and stereoselective glycosylation strategies using unique catalysts such as boronic acids and quinones, enabling the selective formation of 1,2-cis-glycosidic linkages in unprotected substrates. Their work has significantly advanced the synthesis of biologically active glycosides, including isoflavone glycosides and complex oligosaccharides like the lipopolysaccharide repeating unit from *E. coli* O75. The lab also explores DNA-cleaving systems based on quinoxaline derivatives, highlighting their interdisciplinary approach to glycochemistry and molecular recognition.
Professor Yuji Mochizuki's research lab specializes in computational quantum chemistry and molecular simulation, focusing on large-scale biomolecular systems and functional materials. The lab develops and applies advanced quantum mechanical methods—particularly the fragment molecular orbital (FMO) approach—to study electronic interactions, binding affinities, and reaction mechanisms in complex systems such as protein-ligand complexes, viral enzymes, and polymer electrolytes. Their work bridges theoretical chemistry with practical applications in drug discovery, nanotechnology, and clean energy materials. The lab emphasizes high-performance computing to enable accurate, ab initio simulations of systems with thousands of atoms.
Professor Yuya Takahashi's research lab specializes in the multiscale mechanics and durability of cement-based materials, with a focus on alkali–silica reactions (ASR) and freeze–thaw damage in reinforced concrete structures. The lab develops advanced multi-scale computational models—integrating chemo-mechanical, poro-mechanical, and fracture mechanics frameworks—to predict long-term degradation, expansion behavior, and remaining service life under complex environmental and mechanical conditions. Experimental validation is conducted through large-scale specimens and accelerated aging tests, bridging the gap between microscale mechanisms and macroscale structural performance. The lab also applies dynamic game theory to industrial economics, analyzing strategic firm exit behaviors in declining markets, particularly in historical contexts such as the US movie theater industry.
