Dae Sung Yoon

Precise temperature control and rapid thermal cycling in a micromachined DNA polymerase chain reaction chip, Dae Sung Yoon, You-Seop Lee, Youngsun Lee, Hye Jung Cho, Su Whan Sung, Kwang W Oh, Junhoe Cha, Geunbae Lim

Glass-based microchannel chips were fabricated using photolithographic technology, and Pt thin-film microelectrodes, as coplanar impedance sensors, were integrated on them. Longitudinal design parameters, such as interelectrode spacing and electrode width, of coplanar impedance sensors were changed to determine AC frequency characteristics as design parameters. Through developing total impedance equations and modeling equivalent circuits, the dominant components in each frequency region were ill

We have developed a horizontally aligned carbon nanotube sensor that enables not only the specific detection of biomolecules with ultra-sensitivity, but also the quantitative characterization of binding affinity between biomolecules and/or interaction between a carbon nanotube and a biomolecule, for future applications in early diagnostics. In particular, we have fabricated horizontally aligned carbon nanotubes, which were functionalized with specific aptamers that are able to specifically bind

Graphene-based electronic textile (e-textile) gas sensors have been developed for detecting hazardous NO₂ gas. For the e-textile gas sensor, electrical conductivity is a critical factor because it directly affects its sensitivity. To obtain a highly conductive e-textile, biomolecules have been used for gluing the graphene to the textile surface, though there remain areas to improve, such as poor conductivity and flexibility. Herein, we have developed a dopamine-graphene hybrid electro

Ultrasonic treatment (UST) has been used not only to accelerate protein fibril growth and amplify infectious prion proteins from biological fluids, but also to break amyloid-like fibrils for treatment. Despite the applicability of UST to clinical treatment, both the decomposition characteristics of fibrils and the regrowth mechanisms of the decomposed fibrils remain unclear. Here, we report UST-driven decomposition of amyloid-like fibrils into shorter fibrils and the principles of fibril regrowt