Daigo Terutsuki

Small drones with biosensor devices have great potential for detecting odorant molecules in air and can be applied to environmental and security monitoring. To realize these applications, two important factors are considered: first, development of highly sensitive, selective, and real-time odorant sensor devices, and second, construction of a highly maneuverable platform with efficient odor source localization. Previously, small drones with commercial gas sensors or biosensors based on insect an

Field-effect transistor (FET)-based biosensors have a wide range of applications, and a bio-FET odorant sensor, based on insect (Sf21) cells expressing insect odorant receptors (ORs) with sensitivity and selectivity, has emerged. To fully realize the practical application of bio-FET odorant sensors, knowledge of the cell-device interface for efficient signal transfer, and a reliable and low-cost measurement system using the commercial complementary metal-oxide semiconductor (CMOS) foundry proces

An intrinsically soft organic electrode consisting of poly(3,4-ethylenedioxythiophene)-modified polyurethane (PEDOT-PU) is embedded into a bilayer film of polyvinyl alcohol (PVA) hydrogels for developing a self-closing cuff electrode for neuromodulation. The curled form of the PVA hydrogel is prepared by releasing internal stress in the bilayer structure. The inner diameter of the cuff electrode is set to less than 2 mm for immobilization to the vagus nerve (VN) of humans and pigs. The stability

Small drones with chemical or biosensor devices that can detect airborne odorant molecules have attracted considerable attention owing to their applicability in environmental and security monitoring and search-and-rescue operations. Small drones with commercial metal-oxide-semiconductor (MOX) gas sensors have been developed for odor source localization; however, their real-time-odor-detection performance has proven inadequate. However, biosensing technologies based on insect olfactory systems ex

We here propose a completely novel bio-hybrid electronic odorant sensor, termed odor-sensitive field effect transistor (OSFET), which was developed based on insect cells expressing insect odorant receptors (ORs). Living cells of the fall armyworm (Spodoptera frugiperda: Sf21 cells) were integrated over a CMOS post-processed Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="h

The advent of 3D-printing technologies has had a significant effect on the development of medical and biological devices. Perfusion chambers are widely used for live-cell imaging in cell biology research; however, air-bubble invasion is a pervasive problem in perfusion systems. Although 3D printing allows the rapid fabrication of millifluidic and microfluidic devices with high resolution, little has been reported on 3D-printed fluidic devices with bubble trapping systems. Herein, we present a 3D

Abstract Spatiotemporally controlled chemical delivery is crucial for various biomedical engineering applications. Here, a novel concept of electrically controllable delivery utilizing electroosmotic flow (EOF) generated in a combination of anionic and cationic hydrogels (A‐ and C‐hydrogels) is reported. The unique advantages of the A/C‐hydrogel combination are demonstrated utilizing a flexible sheet‐shaped and a thin tubular devices. Since the directions of EOF in the A‐ and C‐hydrogels are opp

Abstract Hydrogel‐based soft, wet devices receive a great deal of attention in advanced medical engineering, which will require integration of hydrogels and elastomers through a transparent and tightly bound interface. Here, the strength of the mechanical interlock of the hydrogel–elastomer interface is studied using microstructured poly(dimethylsiloxane) (PDMS) sheets embedded in a polyvinyl alcohol (PVA) hydrogel. The PDMS sheet, which exhibits micro‐protrusions (cuboid and frustum‐shape), has

Odours used by insects for foraging and mating are carried by the air. Insects induce airflows around them by flapping their wings, and the distribution of these airflows may strongly influence odour source localisation. The flightless silkworm moth, Bombyx mori, has been a prominent insect model for olfactory research. However, although there have been numerous studies on antenna morphology and its fluid dynamics, neurophysiology, and localisation algorithms, the airflow manipulation of the B.

A common approach in concept selection methods is to gather customer requirements and needs based upon missions or operational scenarios; these requirements and needs lead to objectives that are useful in concept selection methods. However, when introducing new, cutting-edge technology, it is extremely hard for researchers or developers to gather customer requirements because customers do not fully understand (or even know) the capabilities of the new technology. In this paper, a small ornithopt

A porous microneedle (PMN)-based potentiometric ion sensor for transdermal monitoring of electrolytes in the interstitial fluid was developed. The carbon coating with an ion-selective membrane was formed on half of the needle tip as the working electrode, while the Ag/AgCl reference electrode was mounted on the PMN chip. This design of a single needle-type configuration allows lower invasive transdermal sensing than the conventional system with multiple needle electrodes. The fabricated potentio

Small drones with chemical or biosensor devices that can detect airborne odorant molecules have attracted considerable attention owing to their applicability in environmental and security monitoring and search-and-rescue operations. Small drones with commercial metal-oxide-semiconductor (MOX) gas sensors have been developed for odor source localization; however, their real-time-odor-detection performance has proven inadequate. However, biosensing technologies based on insect olfactory systems ex