Yonsei University · Dentistry
Professor Daniel S. Thoma's research lab specializes in periodontal and implant dentistry, focusing on soft tissue augmentation, peri-implant health, and clinical outcomes of various grafting techniques. The lab investigates the efficacy of autogenous and alternative graft materials—such as connective tissue grafts (SCTG), free gingival grafts (FGG), and xenografts—in enhancing keratinized mucosa, mucosal thickness, and long-term implant stability. Key research directions include comparative evaluations of surgical techniques, patient-reported outcomes, and long-term survival rates of dental implants, particularly in challenging anatomical sites like the posterior maxilla with sinus augmentation. The lab emphasizes evidence-based clinical decision-making, aiming to optimize both functional and aesthetic outcomes in implant and periodontal therapy.
Figures are computed from collected data and may differ slightly.
Within the limitations of this review, it was concluded that soft tissue grafting procedures result in more favorable peri-implant health: (i) for gain of keratinized mucosa using autogenous grafts with a greater improvement of bleeding indices and higher marginal bone levels; (ii) for gain of mucosal thickness using autogenous grafts with significantly less marginal bone loss.
The purpose of this review was to assess the scientific and clinical bases for the proposed classification of periodontitis. The clinical and histopathological signs and the etiology of periodontitis were described. Cross-sectional studies were analyzed to determine when onset of periodontitis most frequently occurs in adults. In addition, the progression rates of periodontitis have been assessed from longitudinal studies. No clinical, histopathological, or microbiological features could be iden
An APF/V plus FGG/SCTG was the best-documented and most successful method to increase the width of KM. APF/V plus CM demonstrated less gain in KM, but also less patient morbidity and surgery time compared to APF/V plus SCTG based on two RCTs. Autogenous grafts (SCTG) rendered an increase in soft tissue thickness and better aesthetics compared to non-grafted sites.
APF/V is a successful treatment concept to increase the width of keratinized tissue or attached gingiva around teeth. The addition of autogenous tissue statistically significantly increases the width of attached gingiva. For soft tissue volume augmentation, only limited data are available favoring SCTGs over FGG.
Soft tissue augmentation at implant sites resulted in a similar or higher soft tissue volume increase after 90 days for VCMX versus SCTG. PROMs did not reveal relevant differences between the two groups.
The outcomes of the survey analyses demonstrated predictably high implant survival rates for short implants and longer implants placed in augmented sinus and their respective reconstructions. Given the higher number of biological complications, increased morbidity, costs and surgical time of longer dental implants in the augmented sinus, shorter dental implants may represent the preferred treatment alternative.
Dental implants have proven to be a successful treatment option in fully and partially edentulous patients, rendering long-term functional and esthetic outcomes. Various factors are crucial for predictable long-term peri-implant tissue stability, including the biologic width; the papilla height and the mucosal soft-tissue level; the amounts of soft-tissue volume and keratinized tissue; and the biotype of the mucosa. The biotype of the mucosa is congenitally set, whereas many other parameters can
Despite the high survival rate of RBBs after 5 and 10 years, technical complications like de-bonding and minor chipping were frequent. RBBs with zirconia framework and RBBs with one retainer tooth showed the highest survival rate.
Abstract Objectives To analyse the evidence regarding the efficacy of lateral bone augmentation procedures in terms of defect resolution in cases of horizontal ridge deficiencies after implant placement. Materials and Methods Included studies met the following inclusion criteria: randomized controlled trials ( RCT s) or controlled clinical trials ( CCT s), re‐entry procedure to assess defect resolution, minimum of 10 patients (5 per group). Meta‐analyses were performed whenever possible, includi
This study assessed defect depth and volume resulting from root instrumentation using a piezoelectric ultrasonic scaler with a slim scaling tip in vitro. Combinations of the following working parameters were analyzed: lateral forces of 0.5 N, 1 N, and 2 N; tip angulations of 0 degrees, 45 degrees, and 90 degrees; power settings of low, medium and high; and instrumentation time of 10 s, 20 s, 40 s, and 80 s. Defects were quantified using a 3D optical laser scanner. Overall, lateral force had the
Within the limits of this animal study, the CM may serve as a replacement for autogenous connective tissue.
VCMX and SCTG can be used for soft tissue augmentation at implant sites resulting in an at least short-term increase in volume.
The available evidence suggested that submucosal debridement with adjunctive local delivery of antibiotics, submucosal glycine powder air polishing, or Er:YAG laser treatment may reduce clinical signs of peri-implant mucosal inflammation to a greater extent relative to submucosal debridement using curettes with adjunctive irrigation with chlorhexidine. Long-term randomized controlled trials are needed to assess the efficacy of non-surgical therapy on progressing bone loss, implant survival rates
The management and prevention of soft tissue complications is of key importance in modern implant dentistry and influences biologic and esthetic outcomes. The assessment of the soft tissue conditions from a quantitative and qualitative perspective should, therefore, be part of the overall treatment plan. Such an assessment dictates a potential indication as well as an ideal time point for additional soft tissue management. A proper risk assessment and management of the soft tissues at the planne
48 adult patients with untreated periodontitis harboring subgingival Actinobacillus actinomycetemcomitans and/or Porphyromonas gingivalis as assessed by PCR were randomly assigned to receive full-mouth scaling alone (control) or scaling with systemic metronidazole plus amoxicillin and supragingival irrigation with chlorhexidine digluconate (test). In patients harboring A. actinomycetemcomitans intraorally at baseline, the adjunctive antimicrobial therapy resulted in a significantly higher incide
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