Dong Kun Lee

Androgen receptor (AR) may communicate with the general transcription machinery on the core promoter to exert its function as a transcriptional modulator. Our previous report demonstrated that the AR interacted with transcription factor IIH (TFIIH) under physiological conditions and that overexpression of Cdk-activating kinase, the kinase moiety of TFIIH, enhanced AR-mediated transcription in prostate cancer cells. In an effort to further dissect the mechanisms implicated in AR transactivation,

The androgen receptor (AR), like other steroid receptors, modulates the activity of the general transcription machinery on the core promoter to exert its function as a regulator. Co-immunoprecipitation of prostate cancer LNCaP cell extract using protein A-Sepharose coupled with anti-AR antibody indicates that the AR interacts with the general transcription factor TFIIH in a physiological condition. Co-transfection of cdk activating kinase (CAK), the kinase moiety of TFIIH, enhanced AR-mediated t

The mounting mental health issues faced by elderly urban residents increase the social and economic costs to society associated with dementia and depression. Therefore, it is necessary to identify the characteristics of elderly urban residents suffering from mental health issues, to address these issues more effectively. We used 2015 Community Health Survey data from the Korea Centers for Disease Control and Prevention to identify the demographic and social characteristics of 11,408 elderly urba

Trees in urban areas have significant effects on the urban ecosystem. They can be used to improve the water cycle in urban areas by increasing evaporation and reducing runoff through rainfall interception. Street trees placed in planters on impervious areas reduce runoff by intercepting rainfall and by temporarily storing raindrops on leaves. Therefore, understanding tree canopy geometry and the effect of rainfall interception is important in urban hydrology. In this study, we assessed the effec

Forest fires are one of the most frequently occurring natural hazards, causing substantial economic loss and destruction of forest cover. As the Gangwon-do region in Korea has abundant forest resources and ecological diversity as Korea's largest forest area, spatial data on forest fire susceptibility of the region are urgently required. In this study, a forest fire susceptibility map (FFSM) of Gangwon-do was constructed using Google Earth Engine (GEE) and three machine learning algorith

Green space is fundamental to the quality of life of residents, and as such, urban planning or improvement projects often include strategies directly or indirectly related to greening. Although green space is well established to generate positive effects such as cooling, runoff reducing, and ecological corridor, a few studies have examined the comprehensive process of greening in the urban planning context. To fill this gap in the literature, this study seeks to identify a planning model that de

The role that psychological variables play in depression among elderly urban residents has received little research attention. Therefore, the purpose of this study was to examine the relationships between social capital, social capital satisfaction, self-esteem, and depression among elderly urban residents. We used the responses provided by 701 elderly persons to scales assessing social capital (i.e., network, trust), social capital satisfaction, self-esteem, and depression, as part of the Korea

Increased impervious surfaces due to urbanization have reduced evaporation and infiltration into the soil compared with existing natural water cycle systems, which causes various problems, such as urban floods, landslides, and deterioration of water quality. To effectively solve the urban water cycle issue, green infrastructure using urban green space has emerged to reduce runoff and increase evaporation. It has the advantage of restoring the water cycle system of urban areas by complementing th