Hanyang University · Medicine
Professor Dongho Choi's research lab specializes in biomedical and civil engineering applications, focusing on cancer biology in transplant recipients and the structural performance of innovative infrastructure systems. The lab investigates cancer incidence and survival patterns in solid organ transplant populations, particularly in East Asia, while also exploring the dynamic behavior and optimal design of submerged floating tunnels under extreme environmental loads. Research spans from molecular markers in colorectal cancer to biomechanical modeling of suspension bridges and embryonic stem cell differentiation. The lab integrates clinical epidemiology with advanced structural and biological modeling to address critical challenges in healthcare and civil infrastructure.
Figures are computed from collected data and may differ slightly.
CD markers were related to invasiveness and differentiation of colorectal adenocarcinoma. However, CD expression was not closely related to survival.
Embryonic stem (ES) cells have the potential to differentiate into all three germ layers, providing new perspectives not only for embryonic development but also for the application in cell replacement therapies. Even though the formation of an embryoid body (EB) in a suspension culture has been the most popular method to differentiate ES cells into a wide range of cells, not much is known about the characteristics of EB cells. To this end, we investigated the process of EB formation in the suspe
Submerged floating tunnels (SFTs) are innovative structural solutions to waterway crossings, such as sea-straits, fjords and lakes. As the width and depth of straits increase, the conventional structures such as cable-supported bridges, underground tunnels or immersed tunnels become uneconomical alternatives. For the realization of SFT, the structural response under extreme environmental conditions needs to be evaluated properly. This study evaluates the displacements and internal forces of SFT
This paper proposes an equivalent suspension bridge model for the preliminary design of support towers of suspension bridges. In this simplified model, the bridge is composed of its support towers, with equivalent springs replacing suspension cables and girders. An explicit formula for the spring stiffness was derived for the horizontal stiffness at the end of an inclined main cable and compared with Ernst’s formula as well as finite-element analysis results. For the analysis of the model, dead
The cancer risk among solid organ transplantation recipients in East-Asia has been insufficiently studied. This study estimated de novo cancer incidence in kidney and liver recipients 2008-2015, compared with the general population in Korea using nationwide data. This is a retrospective cohort study using nationwide health insurance claims data. The study population was comprised of cancer-free 10,085 kidney recipients and 3,822 liver recipients. Standardized incidence ratio (SIR) of cancer usin
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