Korea Advanced Institute of Science and Technology · Engineering
Professor Dong-Soo Kim's research lab specializes in biomedical engineering and geotechnical systems, focusing on low-current measurement technologies for biomedical applications and the mechanical behavior of foundation systems under dynamic loads. The lab investigates noise optimization in electronic circuits for sensitive biological signal detection and explores innovative foundation designs—such as piled rafts and rocking foundations—to enhance structural resilience in seismic zones. Research also extends to pharmacological mechanisms, particularly the psychoneuroimmunological effects of modafinil and the regulation of vascular signaling pathways involving PDE1A1 and cGMP in nitrate tolerance. These interdisciplinary efforts bridge electronics, biomedicine, and civil engineering to address clinical and infrastructural challenges.
Figures are computed from collected data and may differ slightly.
Induction of PDE1A1 in nitrate-tolerant vessels may be one mechanism by which NO/cGMP-mediated vasodilation is desensitized and Ca(2+)-mediated vasoconstriction is supersensitized. Inhibiting PDE1A1 expression and/or activity could be a novel therapeutic approach to limit nitrate tolerance.
In this paper, we report on the noise analysis of low current measurement systems for biomedical applications and their fundamental limits. We analyzed resistive feedback, capacitive feedback and current amplifier circuits for low current measurement systems. Detailed noise analysis for different biomedical applications are presented and matched with measurement data using a 0.5-μm fabrication process. Based on the theoretical analysis and the corresponding measurement results, the capacitive fe
Modafinil can be used by anyone, who wishes to work late, stay awake, enhance their cognitive reactions, or brighten their moods. Users may already be under a great level of stress, i.e. cancer patients or soldiers in a battle field. A psychoneuroimmunological approach is thus needed to investigate the multi-functional effects of modafinil.
In this article, site response analyses for 124 sites collected in Korea were performed to evaluate earthquake ground motions in regions of shallow bedrock in Korea. Based on the results, a new two-parameter site classification system was developed for use in regions of shallow bedrock. The system incorporates depth to bedrock and mean VS of soil above bedrock as parameters for site classification instead of VS30. Soil sites were divided into seven site classes and the corresponding site coeffic
In the design of piled raft foundations, the control of total and differential settlements is crucial. On the basis of centrifuge tests, this study presents the feasibility of a fairly optimal pile arrangement scheme for reducing total and differential settlements. Two models of piled raft foundations having the same flexible raft and number of piles, the uniform pile arrangement model and the concentrated pile arrangement model, and one model having a rigid raft with a concentrated pile arrange
Open papers in the app to read, cite, and organize with AI.
