Sungkyunkwan University · Pharmacology, Toxicology and Pharmaceutics
Professor Eun-Seok Park's research lab specializes in pharmaceutical and materials science, focusing on advancing drug delivery systems and developing novel formulations for improved therapeutic efficacy. Key research directions include enhancing drug solubility and bioavailability through techniques like spray drying and cocrystal engineering, designing transdermal patches with optimized permeation properties, and exploring natural compounds for their pharmacological potential. The lab also investigates electrolyte systems for next-generation lithium metal batteries, emphasizing interfacial stability and electrochemical performance.
Figures are computed from collected data and may differ slightly.
1,2-Dimethoxyethane (DME) has been widely used as an electrolyte solvent for lithium metal batteries on account of its intrinsic reductive stability; however, its low oxidative stability presents a major challenge for use in high-voltage Li metal batteries (LMBs). In this direction, herein, we introduce a new low-dielectric solvent, 1,2-dimethoxypropane (DMP), as an electrolyte solvent. Compared to DME, DMP has decreased solvation power owing to its increased steric effects, thus promoting anion
A solid dispersion of rebamipide was successfully formulated using the spray-drying method. Bioavailability and efficacy of rebamipide were increased significantly by solubility enhancement of the drug.
<i>Centipeda minima</i> (L.) A. Braun & Asch is a well-studied plant in Chinese medicine that is used for the treatment of several diseases. A recent study has revealed the effects of extract of <i>Cetipeda minima</i> (CMX) standardized by brevilin A in inducing hair growth. However, the mechanism of action of CMX in human hair follicle dermal papilla cells (HFDPCs) has not yet been identified. We aimed to investigate the molecular basis underlying the effect of CMX on hair growth in HFDPCs. CMX
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