Yonsei University · Medicine
Professor Gregory Y.H. Lip's research lab specializes in cardiovascular medicine, with a primary focus on stroke prevention and anticoagulation therapy in patients with atrial fibrillation (AF). The lab develops and validates clinical risk stratification tools—such as the CHA₂DS₂–VASc and HAS-BLED scores—to improve risk assessment for stroke and bleeding, aiming to optimize antithrombotic decision-making in real-world settings. Their work emphasizes practical, evidence-based tools that enhance patient safety and clinical outcomes in atrial fibrillation management. The lab also investigates the integration of risk scores into clinical guidelines and digital health tools to support personalized medicine.
Figures are computed from collected data and may differ slightly.
Our novel, simple stroke risk stratification schema, based on a risk factor approach, provides some improvement in predictive value for TE over the CHADS(2) schema, with low event rates in low-risk subjects and the classification of only a small proportion of subjects into the intermediate-risk category. This schema could improve our approach to stroke risk stratification in patients with AF.
This simple, novel bleeding risk score (HAS-BLED) provides a practical tool to assess the individual bleeding risk of real-world patients with AF, potentially supporting clinical decision making regarding antithrombotic therapy in patients with AF.
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