Tohoku University · Medicine
Professor Hiroki Kurita's research lab specializes in stereotactic radiosurgery and radiosurgical outcomes in cerebrovascular and neurological disorders, with a focus on arteriovenous malformations (AVMs), cavernous sinus meningiomas, and epilepsy-related AVMs. The lab investigates both the clinical efficacy and early biological effects of radiation on neural tissues, including radiation-induced apoptosis in white matter and histological changes following radiosurgery. Additionally, the lab explores advanced materials for biomedical and structural applications, such as carbon nanotube-reinforced metal matrix composites. These diverse research directions reflect a strong translational focus, bridging clinical neurosurgery with experimental neuroscience and materials science.
Figures are computed from collected data and may differ slightly.
Radiosurgery is a viable treatment modality for patients with small deep parenchymal brain stem AVMs. A standard radiosurgical dose is safe and effective when directed to a small treatment volume. However, latent interval haemorrhage remains a significant problem until the nidus is obliterated completely.
Radiosurgery seems to be beneficial for seizure control in patients with unruptured epileptogenic AVM.
The authors report a rare case of a patient with a chronic encapsulated expanding hematoma and progressive neurological deterioration who presented 2 years after gamma knife radiosurgery for a cerebral arteriovenous malformation (AVM). A tough capsule containing multiple layers of organized hematoma resulting from previous bleeding was confirmed surgically. Histological examination revealed that the capsule consisted of a dense collagenous outer layer and a granulomatous newly vascularized inner
Although radiation injuries to the brain are well documented, immediate early histological changes in the brain remain to be defined. The present study characterizes glial injury provoked in adult rat white matter within 24 h after a single irradiation of the whole brain (10 or 20 Gray). Irradiated brains were histologically and histochemically analyzed. TUNEL-positive cells exhibiting apoptotic morphology were counted in five representative regions of the white matter. Glial cell death was furt
Gamma-knife radiosurgery is a valuable addition to surgical removal in the treatment of cavernous sinus meningiomas. Combination of non-radical resection and subsequent radiosurgery is recommended to improve treatment-associated morbidity.
Multi-walled carbon nanotubes (MWCNTs) with outstanding mechanical properties are considered as an ultimate reinforcement for conventional metals such as aluminum (Al), though they require uniform dispersion and intimate contacts with the host metal matrix. However, bundled structure of chemically stable, pristine MWCNTs has been the main challenge to achieving the expected structural reinforcement. In addition, the sole contribution of MWCNTs in strengthening the metal matrix has not been recog
A portion of occipital AVMs do cause headaches that satisfy the current IHS criteria for migraine, and the prevalence varies by the topography of the lesion. Radiosurgery can resolve headaches in the majority of treated patients.
Cellulose nanofibers (CNF) have recently attracted attention as one of the reinforcements for composite materials. However, the same as other nanofibers, CNFs can be easily agglomerated and the nano-level defibration is necessary to obtain their outstanding properties in polymer matrices. To overcome this issue, two major defibration methods, chemical and mechanical defibration have been considered. The chemically-defibrated CNF is expensive and so prevents the practical realization of CNF as ge
Energy harvesting using magnetostrictive materials is currently attracting significant attention. The additive manufacturing process can produce such materials with excellent energy-harvesting performance and various required properties, including mechanical properties—by optimizing the lattice structure of the material. This study optimized the manufacturing parameters of a laser powder bed fusion process to produce a magnetostrictive Fe52–Co48 alloy. We evaluated the energy-harvesting performa
This paper reports on an operation framework for autonomous rice harvesting. We developed an integrated algorithm for robotic operation and cooperation with farmworkers to automate each subsection of the harvesting and unloading process and of the processes that bridge them (homing and restarting). The algorithm was installed into a head‐feeding combine robot. The robot followed a target path based on its absolute position and orientation, planning a counterclockwise spiral path in a rectangular
The authors report two patients with a rare complication of parent artery narrowing that occurred 3 and 6 months after aneurysm surgery. In both cases, the stenosed arteries had been wrapped around their entire circumferences with neurosurgical sponge (cotton linter) and coated with plastic adhesive (cyanoacrylate compounds) and the aneurysmal neck had been clipped. This reinforcement procedure was considered to have caused the unusual delayed arterial narrowing. The importance of avoiding circu
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