The University of Osaka · Materials Science
Professor Hiroyasu Yamaguchi's research lab specializes in advanced materials science and plant biotechnology, focusing on the design of stimuli-responsive self-assembled materials through molecular recognition and the application of ion beams in mutation breeding. The lab explores photoresponsive systems, particularly using azobenzene and cyclodextrin interactions, to create tunable hydrogels and functional macroscopic materials. In parallel, the lab investigates the use of heavy ion beams for inducing targeted genetic mutations in ornamental and crop plants, aiming to develop novel cultivars with improved traits. Their interdisciplinary work bridges supramolecular chemistry, polymer science, and plant genetics to address challenges in materials innovation and sustainable agriculture.
Figures are computed from collected data and may differ slightly.
The formation of effective and precise linkages in bottom-up or top-down processes is important for the development of self-assembled materials. Self-assembly through molecular recognition events is a powerful tool for producing functionalized materials. Photoresponsive molecular recognition systems can permit the creation of photoregulated self-assembled macroscopic objects. Here we demonstrate that macroscopic gel assembly can be highly regulated through photoisomerization of an azobenzene moi
We investigated the usefulness of ion beams for mutation breeding in rice (Oryza sativa L.) by comparing the efficiency (i.e., the ratio of desirable mutations to plant damage such as lethality and sterility), mutation rate, spectrum, and optimum dose to that of gamma rays. Rice seeds were irradiated with carbon ions (mean linear energy transfer = 76 and 107 keV/μm), helium ions (9 keV/μm), and gamma rays, and their survival and fertility were examined in the M1 generation. The frequency of chlo
We investigated the effect of total irradiation dose and dose rate on flower color mutation and nuclear DNA content as an index of radiation damage in chrysanthemum. Chrysanthemum morifolium cv. ‘Taihei’ plants grown by in vitro culture were gamma-irradiated with a total dose of 15, 30 and 60 Gy at a rate of 0.5, 1, 2 and 5 Gy/h. Leaf explants cut from the irradiated plants were tissue cultured, and the regeneration rates and frequency of flower color mutation were investigated. Nuclear DNA cont
ADVERTISEMENT RETURN TO ISSUECommunication to the...Communication to the EditorNEXTSelf-Assembly of Gels through Molecular Recognition of Cyclodextrins: Shape Selectivity for Linear and Cyclic Guest MoleculesHiroyasu Yamaguchi†, Ryosuke Kobayashi†, Yoshinori Takashima†, Akihito Hashidzume†, and Akira Harada*†‡View Author Information† Department of Macromolecular Science, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan‡ Japan Science and Technology Agency (JST), Core
Ornamental plants that have a rich variety of flower colors and shapes are highly prized in the commercial flower market, and therefore, mutant cultivars that produce different types of flowers while retaining their growth habits are in demand. Furthermore, mutation breeding is well suited for ornamental plants because many species can be easily vegetatively propagated, facilitating the production of spontaneous and induced mutants. The use of ion beams in mutation breeding has rapidly expanded
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