Sungkyunkwan University · Medicine
Professor Hyo Yeol Kim's research lab specializes in otorhinolaryngology and sleep medicine, with a focus on the pathophysiology of chronic rhinosinusitis (CRS), the role of inflammatory mediators such as HP in disease progression, and the impact of systemic factors like statins on mucosal healing and olfactory recovery. The lab investigates upper and lower airway interactions, particularly in the context of sleep-disordered breathing, using both preclinical models and clinical studies to explore anatomical and physiological determinants of airway obstruction. Their work also emphasizes early diagnosis and management of comorbid lower airway diseases in patients with sinonasal disorders.
Figures are computed from collected data and may differ slightly.
HP has a limited role in pathogenesis of CRS.
The anatomic level and the degree of pharyngeal narrowing observed during FNMM revealed a correlation with the AHIs of different sleeping positions.
Statins are associated with recovery of olfaction after 3MI injection in a mouse model.
Thirty patients (41.1%) had lower airway diseases. There were 8 patients with asthma, 5 with asymptomatic bronchial hyperresponsiveness, 11 with small airway disease, 2 with chronic obstructive pulmonary disease and 4 with bronchiectasis. Of these 30 patients, 21 patients (70.0%) were first diagnosed as having lower airway diseases in this study.
Upper airway occlusion including nasal obstruction or tonsillar hypertrophy might increase the effective CPAP level.
Fungal rhinosinusitis with mucosal invasion is different from fungal ball and invasive fungal rhinosinusitis and may be classified in a separate category as microinvasive FRS.
Patients with paradoxical nasal obstruction might be explained by less degree of mucosal change in the concave side of the nasal cavity during nasal cycle than the control group.
The severity of SDB and the quality of sleep are well correlated with the MMS, and especially for the patients with nasal obstruction. The MMS can give more valuable information about the severity of SDB when combined with simple questions about nasal obstruction.
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