Sungkyunkwan University · Medicine
Professor Hyunjin Park's research lab specializes in medical image analysis and radiomics, with a focus on advancing diagnostic and treatment planning tools in oncology and neurology. The lab develops innovative imaging techniques such as probabilistic atlases, parametric PET/MRI, and radiomics signatures to improve the detection and prognosis of diseases like prostate cancer and breast cancer. It also investigates brain network alterations in neurodevelopmental disorders such as autism spectrum disorder using advanced fMRI analysis. The lab emphasizes reproducible, data-driven methodologies by integrating cutting-edge neuroimaging software pipelines.
Figures are computed from collected data and may differ slightly.
There have been significant efforts to build a probabilistic atlas of the brain and to use it for many common applications, such as segmentation and registration. Though the work related to brain atlases can be applied to nonbrain organs, less attention has been paid to actually building an atlas for organs other than the brain. Motivated by the automatic identification of normal organs for applications in radiation therapy treatment planning, we present a method to construct a probabilistic atl
<b>Purpose:</b> To develop a radiomics signature based on preoperative MRI to estimate disease-free survival (DFS) in patients with invasive breast cancer and to establish a radiomics nomogram that incorporates the radiomics signature and MRI and clinicopathological findings.<b>Experimental Design:</b> We identified 294 patients with invasive breast cancer who underwent preoperative MRI. Patients were randomly divided into training (<i>n</i> = 194) and validation (<i>n</i> = 100) sets. A radiomi
CH-BSLNs showed good protection for deltamethrin against photodegradation. This novel nanocarrier may be useful in crop protection as an economical strategy to enhance the effect of pesticides in the field and protect the environment as well.
Our data indicate that parametric PET/MRI using P(CHOL/ADC) improves lesion-to-background contrast (TBRs) of Gleason ≥ 3 + 4 disease, compared with (11)C-choline PET/CT or diffusion-weighted MRI, and thus hold promise that parametric imaging performed on hybrid PET/MRI may further improve identification and localization of significant primary prostate cancer.
Autism spectrum disorder (ASD) is a neurodevelopmental disability with global implication. Altered brain connectivity in the language network has frequently been reported in ASD patients using task-based functional magnetic resonance imaging (fMRI) compared to typically developing (TD) participants. Most of these studies have focused on a specific age group or mixed age groups with ASD. In the current study, we investigated age-related changes in functional connectivity related measure, degree c
The preprocessing of functional magnetic resonance imaging (fMRI) data is necessary to remove unwanted artifacts and transform the data into a standard format. There are several neuroimaging data processing tools that are widely used, such as SPM, AFNI, FSL, FreeSurfer, Workbench, and fMRIPrep. Different data preprocessing pipelines yield differing results, which might reduce the reproducibility of neuroimaging studies. Here, we developed a preprocessing pipeline for T1-weighted structural MRI a
Obesity causes critical health problems including diabetes and hypertension that affect billions of people worldwide. Obesity and eating behaviors are believed to be closely linked but their relationship through brain networks has not been fully explored. We identified functional brain networks associated with obesity and examined how the networks were related to eating behaviors. Resting state functional magnetic resonance imaging (MRI) scans were obtained for 82 participants. Data were from an
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