Hanyang University · Medicine
Professor Jae-Won Oh's research lab specializes in environmental and clinical immunology, focusing on the impact of airborne allergens—particularly pollen—on respiratory health and allergic diseases. The lab investigates the epidemiology, seasonal patterns, and climate-driven changes in pollen distribution and their correlation with allergic sensitization, especially in children. Research also extends to viral interactions with the immune system, examining how pollen exposure may modulate antiviral responses, including those to SARS-CoV-2. The lab integrates large-scale environmental monitoring with clinical immunology to improve allergy forecasting and public health strategies.
Figures are computed from collected data and may differ slightly.
Little is known about the prevalence of atopic dermatitis and food allergy outside North America and Europe. We evaluated the prevalence of atopic dermatitis and food allergy with the comparison of prevalence between 1995 and 2000 in Korea and evaluated the correlation of prevalence between atopic dermatitis and food allergy. A cross-sectional questionnaire survey was conducted on random samples of schoolchildren 6 to 14 yr at two time points, 1995 and 2000 throughout Korea. The last twelve mont
Pollen exposure weakens the immunity against certain seasonal respiratory viruses by diminishing the antiviral interferon response. Here we investigate whether the same applies to the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is sensitive to antiviral interferons, if infection waves coincide with high airborne pollen concentrations. Our original hypothesis was that more airborne pollen would lead to increases in infection rates. To examine this, we performed a
Little is known about the prevalence of atopic dermatitis and food allergy outside North America and Europe. We evaluated the prevalence of atopic dermatitis and food allergy with the comparison of prevalence between 1995 and 2000 in Korea and evaluated the correlation of prevalence between atopic dermatitis and food aller-gy. A cross-sectional questionnaire survey was conducted on random samples of schoolchildren 6 to 14 yr at two time points, 1995 and 2000 throughout Korea. The last twelve mon
The old calendar of pollens did not reflect current pollen distribution and concentrations that can be influenced by changes of weather and environment of each region in South Korea. A new pollen calendar of allergenic pollens was made based on the data on pollen concentrations obtained in eight regions nationwide between 1997 and 2009. The distribution of pollen was assessed every day at 8 areas (Seoul, Guri, Busan, Daegu, Jeonju, Kwangju, Kangneung, and Jeju) for 12 years between July 1, 1997
목 적 : 최근 세계적으로 아토피피부염과 함께 여러 알레르기질환의 유병률이 증가하는 추세이며, 특히 소아에서의 발병률은 성인에 비해 훨씬 높은 것으로 알려져 있다. 구미, 유럽에서의 유병률이 매우 높으며 이러한 추세는 치료와 예방이 개선되고 있음에도 불구하고 계속 증가하고 있다. 이에 저자들은 대한소아알레르기 및 호흡기학회 주관으로 1995년과 2000년 초등학생과 중학생, 그리고 2003년 유치원생을 대상으로 전국적인 아토피피부염 유병률의 역학적 변화와 서울과 지방과의 유병률의 차이를 알아보고 아토피피부염을 유발하거나 악화시킬 수 환경적 요인에 대하여도 알아보고자 하였다.방 법 : 1995년과 2000년에 동일한 설문방법을 이용하여 서울과 지방으로 크게 두 군으로 분류하고 나이별로는 초등학생 6-12세군과 중학생 13-15세군으로 분류하여 설문 조사하였으며, 설문 내용은 ISAAC 프로토콜을 한국어로 번역하였으며 일부 환경 설문은 국내현실에 맞게 추가하여 사용하였다. 대상자수는 1
Airborne pollens are one of the common causative and triggering agents of respiratory allergy in a changing planetary environment. A growing number of people worldwide are contracting allergic diseases caused by pollens. The seasonal variations in pollens have occurred everywhere and the sensitization rate to pollens has increased in children as well as in adults. Moreover, allergenic plants, such as ragweed and Japanese hop, grow in soil damaged by human's activities and deforestation with air
The old calendar of pollens did not reflect current pollen distribution and concentrations that can be influenced by changes of weather and environment of each region in South Korea. A new pollen calendar of allergenic pollens was made based on the data on pollen concentrations obtained in eight regions nationwide between 1997 and 2009. The distribution of pollen was assessed every day at 9 stations (Two Seoul sites, Guri, Busan, Daegu, Daejeon, Kwangju, Kangneung, and Jeju) for 12 years and at
The differences between respiratory syncytial virus (RSV) and influenza A virus (IFAV) in the pathogenesis of wheezing in young children have not been clearly defined. The aim of this study was to assess the contributions of RSV vs IFAV in the pathogenesis of upper airway inflammation in wheezy young children. We compared interleukin (IL)-6, IL-8, IL-11, and interferon-gamma (IFN-gamma) levels in nasopharyngeal aspirates (NPA) from non-asthmatic children with respiratory virus infections (RSV in
This study demonstrated the correlation between weather changes and the resulting changes in the pollen season with sensitization rates to allergenic pollens in children living in the Seoul metropolitan area. An annual increase in sensitization rates in younger children was determined. This pattern is expected to continue due to continuing climate change.
A ir-borne pollen is known as one of the major causal agents to respiratory allergic reactions.
In a large number of allergic individuals, inhalant allergens are important causative and triggering agents in respiratory allergies. It is essential to survey the pollen and mold around the patient's environment for the diagnosis and treatment of airborne allergy. Rotorod samplers were installed at well-ventilated places in seven collecting stations in Seoul, the capital of Korea, which has a population of 12 million. Airborne particles carrying allergens were collected daily from each station
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