Seoul National University · Medicine
Professor Jeong Hee Yoon's research lab specializes in quantitative medical imaging, with a focus on non-invasive assessment of liver and pancreatic fibrosis using advanced MRI and elastography techniques. The lab investigates multiparametric MRI, including T2*-corrected Dixon imaging, IVIM diffusion-weighted imaging, and shear-wave elastography, to quantify tissue characteristics such as steatosis, fibrosis, and stiffness. Key research directions include optimizing imaging protocols for improved diagnostic accuracy and reproducibility, particularly in liver fibrosis staging and predicting postoperative complications like pancreatic fistulas.
Figures are computed from collected data and may differ slightly.
MR elastography and SWE shear-wave elastography showed moderate correlation and similar diagnostic performance in the diagnosis of HF hepatic fibrosis of stage F2 or greater; however, MR elastography yielded more reliable LS liver stiffness measurements than did SWE shear-wave elastography .
Multiparametric MR imaging of the pancreas, including imaging with the T2*-corrected Dixon technique and IVIM DW imaging, may yield quantitative information regarding pancreatic steatosis and fibrosis, and f was shown to be significantly associated with postoperative pancreatic fistulas.
Because fECV was shown to increase along with HF progression, the estimation of fECV using routine multiphasic liver CT may have the potential to detect significant HF.
Dt provided better diagnostic performance than ADCtotal in differentiating benign from malignant lesions. Dp and f were significant parameters for diagnosing hypervascular FLLs.
In this study, the optimal minimum number of SWE measurements was 6, and SWE using 6 measurements showed excellent intraobserver reproducibility.
The IVIM-derived parameters and ADC(total) showed significant correlation with HF. The D p showed better diagnostic performance for differentiating significant HF than did ADC(total).
Magnetic resonance imaging (MRI) plays an important role in abdominal imaging. The high contrast resolution offered by MRI provides better lesion detection and its capacity to provide multiparametric images facilitates lesion characterization more effectively than computed tomography. However, the relatively long acquisition time of MRI often detrimentally affects the image quality and limits its accessibility. Recent developments have addressed these drawbacks. Specifically, multiphasic acquisi
Purpose To determine whether hepatocyte uptake ratios derived at gadoxetic acid-enhanced MRI correlate with quantitative measures of liver function and can help to identify contraindication to major hepatectomy. Materials and Methods Between August 2016 and October 2016, 50 study participants with chronic liver disease or cirrhosis underwent liver MRI at 3.0 T including T1 mapping and elastography. Liver function was quantitatively assessed by using the indocyanine green retention test (ICG R<su
Purpose To determine whether B<sub>1</sub> inhomogeneity-corrected volumetric T1 maps of gadoxetic acid-enhanced liver magnetic resonance (MR) imaging are able to demonstrate global liver function and functional heterogeneity in patients with cirrhosis and to investigate their relationship with the development of hepatic insufficiency and decompensation. Materials and Methods This institutional review board-approved retrospective study with waiver of informed consent included 234 consecutive pat
Patients with a risk index ≥2.33 showed a high annual incidence of HCC development in our study, and two-phase LDCT showed significantly higher sensitivity and specificity for HCC detection than US.
MRE and SWE show moderate correlation in their LSMs, although SWE shows higher incidence of unreliable LSMs in cirrhotic liver.
Intrasinus calcifications are different in location and shape between fungal and nonfungal maxillary sinusitis. Although intrasinus calcification is uncommon in nonfungal sinusitis, the CT finding of intrasinus calcification may be helpful for differentiating fungal from nonfungal maxillary sinusitis.
Hepatocellular carcinoma (HCC) can be diagnosed based on characteristic findings of arterial-phase enhancement and portal/delayed "washout" in cirrhotic patients. Several countries and major academic societies have proposed varying specific diagnostic criteria for HCC, largely reflecting the variable HCC prevalence in different regions and ethnic groups, as well as different practice patterns. In 2014, a new version of Korean practice guidelines for management of HCC was released by the Korean L
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