Jieun Kim

Time interval estimation is involved in numerous behavioral processes, but its underlying neural mechanisms remain unclear. In particular, it has been controversial whether time is encoded on a linear or logarithmic scale. Based on our previous finding that inactivation of the medial prefrontal cortex (mPFC) profoundly impairs rat's ability to discriminate time intervals, we investigated how the mPFC processes temporal information by examining activity of mPFC neurons in rats performing a tempor

Polydiacetylene‐based chemosensors are prepared by assembling liposomes of diacetylene monomers with terminal amine groups on an aldehyde‐modified glass substrate, and polymerizing them by irradiation with UV light. Incubation of the immobilized film sensor in a poly(acrylic acid) solution results in a color change from the original blue (solid line in Figure) to the red phase (broken line).

The mechanism by which stimulation of coreceptors such as CD28 contributes to full activation of TCR signaling pathways has been intensively studied, yet quantitative measurement of costimulation effects on functional TCR signaling networks has been lacking. In this study, phosphotyrosine networks triggered by CD3, CD28, or CD3 and CD28 costimulation were analyzed by site-specific quantitative phosphoproteomics, resulting in identification of 101 tyrosine and 3 threonine phosphorylation sites an

Inquiring into concerns surrounding death and the afterlife in an underclass enclave in Japan, this article proposes that the politics of survival involves engaging with the enduring relationship between the living and the dead, referred to as ‘necrosociality’. Based on fieldwork carried out in Yokohama, it explores how ‘isolated death’ ( kodokushi ) and ‘disconnected spirits’ ( muenbotoke ) have become major concerns in homeless activism and support, giving rise to various necrosocial innovatio

In order to investigate the incidence, clinical and microbiologic characteristics of Clostridium difficile infection (CDI) in Korea, a prospective observational study was performed. From September 2008 through January 2010, all patients whose stool was tested for toxin assay A&B and/or C. difficile culture were studied for clinical characteristics. Toxin types of the isolates from stool were tested. The mean incidence of CDI per 100,000 patient-days was 71.6 by month (range, 52.5-114.0), and the

교직헌신은 교수효과성에 상응하는 개념인 반면, 조직 헌신은 업무효과성에 상응하는 개념이다. 이런 개념 구분 하에 본 논문의 질문은 크게 두 가지로 나눌 수 있다. 첫째, 실제 교직헌신이 교수효과성과 더 밀접한 관계를 맺고 있는가? 둘째, 만약 그렇다면 상대적으로 조직 헌신이 떨어지는 교사들의 업무 효과성을 향상시키는 데 리더십이 도움이 되는가? 이를 위해 본 논문은 교직헌신과 리더십이란 각각의 요소들이, 교사들이 산출하는 교수 및 업무효과성 중 어떤 측면에 더 많은 관련을 갖고 있는지 규명하고자 한다. 기존의 연구들은 리더십과 교직헌신간의 유의미한 관계를 밝혀온 데 반해, 본 연구는 교사들의 성취를 교수효과성과 업무효과성으로 구분하고, 교직헌신과 리더십이 교사의 어떤 측면에 더 많은 영향력을 발휘하고 있는지를 밝히는데 그 의미가 있다. 한편 본 연구는 리더와 구성원 전체의 양적 관계를 지향하는 리더십 개념 대신, 리더와 구성원 각자의 질적 관계를 지향하는 리더-부하 관계(LMX) 이

Binary toxin-producing C. difficile infection was not common in Korea and those isolates showed diverse PCR ribotypes with high susceptibility to antimicrobial agents. Glycopeptide use was a risk factor for CDI by those isolates.

The incidence of CDI in Korea has been gradually increasing, and its recent value is as high as that in the United State and Europe. CDI is underestimated, particularly in general hospitals in Korea.

Dermatomyositis (DM) is an idiopathic inflammatory process characterized by proximal muscle weakness and cutaneous lesions, such as the Gottron’s sign, heliotrope rash, and erythematous photosensitive rash. Administration of systemic agents for the treatment of underlying systemic diseases leads to remission of the cutaneous lesions in many cases. However, cutaneous lesions may remain refractory to treatment. Pimecrolimus is a calcineurin inhibitor with combined anti-inflammatory and immunomodul

To assess the prevalence and abundance of antibiotic resistance genes in human and livestock gut microbiomes, 87 humans (healthy individuals and patients with Clostridioides difficile infection (CDI)) and 108 livestock (swine, cattle, and chickens) were enrolled. Gut microbiomes and fluoroquinolone-resistant Escherichia coli isolates were sequenced, and mobile genetic elements adjacent to the β-lactamase (bla) and transferable quinolone resistance (qnr) genes were compared using metagenomic cont