Keio University · Medicine
Professor Kaoru Takabayashi's research lab specializes in gastrointestinal endoscopy and oncology, focusing on advanced endoscopic diagnosis and treatment of inflammatory bowel disease and gastrointestinal cancers. The lab investigates innovative applications of imaging techniques—such as dynamic contrast-enhanced endoscopy—for early detection of conditions like ulcerative colitis-associated neoplasia, and explores minimally invasive therapeutic strategies like endoscopic mucosal resection in complex cases. Additionally, the lab conducts preclinical studies on radiation therapy using I-125 seed implants to evaluate their efficacy across different histological subtypes of gastric cancer, aiming to improve therapeutic precision and outcomes.
Figures are computed from collected data and may differ slightly.
The AI developed here can diagnose UC severity endoscopically similar to IBD expert endoscopists.
endoscopic mucosal resection for a sporadic adenoma located at severe longitudinal ulcer scars in ulcerative colitis Fig.
When a characteristic mucosal pattern, such as a small round or mesh pattern, is found by DCE, the possibility of UCAN should be considered.
The efficacy of conventional radiation therapy for gastric cancer is controversial. In this study, we evaluated the in vitro and in vivo effects of continuous low-dose-rate irradiation by I-125 seeds on different histological types of gastric cancer cell lines. Three human gastric cancer cell lines (MKN74, MKN45, and NUGC4) were treated with or without continuous low-dose irradiation by I-125 seeds in vitro and in vivo. Cell viability, apoptosis, caspase-3 assay, and cell-cycle distribution were
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