Keio University · Medicine
Kazuo Tsubota 교수의 연구실은 눈의 표면 및 눈물막 기능 이상을 중심으로 한 건조안병증(Dry Eye Disease, DED)의 기전과 치료에 중점을 두고 있습니다. 특히 비디오 디스플레이 터미널(VDT) 작업자에서 흔히 나타나는 짧은 눈물막 파손 시간을 기반으로 한 건조안의 병태생리학적 이해를 심화하고 있으며, 자가 혈청 치료나 각막 상피 줄기세포 이식과 같은 새로운 치료 전략 개발에도 기여하고 있습니다. 연구는 임상적 문제 해결을 목표로 하여 기초 생물학적 기전과 실제 치료법의 연계를 추구합니다.
Figures are computed from collected data and may differ slightly.
For the last 20 years, a great amount of evidence has accumulated through epidemiological studies that most of the dry eye disease encountered in daily life, especially in video display terminal (VDT) workers, involves short tear film breakup time (TFBUT) type dry eye, a category characterized by severe symptoms but minimal clinical signs other than short TFBUT. An unstable tear film also affects the visual function, possibly due to the increase of higher order aberrations. Based on the change i
Autologous serum application is a safe and efficient way to provide essential components to the ocular surface in the treatment of dry eye associated with Sjögren's syndrome.
Transplantation of corneal epithelial stem cells can restore useful vision in some patients with severe ocular-surface disorders.
To the Editor: Many persons report ocular fatigue after prolonged work at video display terminals, in part prompting legislation regulating the use of these terminals1. Since one of the main causes...
Over the past decades, the number of patients with dry eye disease (DED) has increased dramatically. The incidence of DED is higher in Asia than in Europe and North America, suggesting the involvement of cultural or racial factors in DED etiology. Although many definitions of DED have been used, discrepancies exist between the various definitions of dry eye disease (DED) used across the globe. This article presents a clinical consensus on the definition of DED, as formulated in four meetings wit
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