Tohoku University · Medicine
Professor Keiichi Jingu's research lab specializes in radiation oncology, with a focus on improving local control and survival outcomes for patients with oligometastatic and recurrent cancers. The lab investigates the efficacy of stereotactic body radiotherapy (SBRT) and chemoradiotherapy in treating pulmonary oligometastases from colorectal cancer and recurrent esophageal cancer, emphasizing dose escalation and combination therapies. Key research directions include optimizing radiotherapy protocols, evaluating treatment response, and identifying prognostic factors in challenging clinical scenarios.
Figures are computed from collected data and may differ slightly.
Our meta-analysis indicated that local control of pulmonary oligometastases from colorectal cancer by stereotactic body radiotherapy was significantly worse than that of pulmonary metastases from other cancers; however, our results also indicated that good local control of pulmonary oligometastases from colorectal cancer can be achieved by dose escalation.
Radiotherapy combined with nedaplatin and 5-FU is a safe and effective salvage treatment for postoperative loco-regional recurrent esophageal cancer. However, the prognosis of patients with multiple regional recurrence or anastomotic recurrence is very poor.
Radiotherapy combined with nedaplatin and 5-FU is a safe and effective salvage treatment for postoperative locoregional recurrent esophageal cancer.
Dose escalation and adjuvant chemotherapy might improve local control in SBRT for pulmonary oligometastases from colorectal cancer.
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