Tohoku University · Mathematics
Professor Kentarou Fujie's research lab specializes in the mathematical analysis of partial differential equations arising in biological and biomedical contexts, particularly focusing on chemotaxis systems that model cell migration and tissue invasion. The lab investigates the existence, boundedness, and long-term behavior of solutions to parabolic-parabolic and parabolic-elliptic chemotaxis models with nonlinear, signal-dependent sensitivity functions. A central theme is understanding how biological mechanisms—such as extracellular matrix dynamics and feedback regulation—impact the stability and global behavior of solutions in bounded, smooth domains, especially in two and three spatial dimensions. The work often bridges theoretical analysis with applications in cancer invasion and wound healing.
Figures are computed from collected data and may differ slightly.
This paper deals with the chemotaxis system\[\begin{cases}u_t=\Delta u - \nabla \cdot (u\nabla v),\qquad x\in \Omega, \ t>0, \\v_t=\Delta v + wz,\qquad x\in \Omega, \ t>0, \\w_t=-wz,\qquad x\in \Omega, \ t>0, \\z_t=\Delta z - z + u, \qquad x\in \Omega, \ t>0,\end{cases}\]in a smoothly bounded domain $\Omega \subset \mathbb{R}^n$, $n \le 3$,that has recently been proposed as a model for tumor invasionin which the role of an active extracellular matrix is accounted for. It is shown that for any ch
This paper deals with the parabolic–elliptic Keller–Segel system with signal-dependent chemotactic sensitivity function, under homogeneous Neumann boundary conditions in a smooth bounded domain , with initial data satisfying u0 ≥ 0 and . The chemotactic sensitivity function χ(v) is assumed to satisfy The global existence of weak solutions in the special case is shown by Biler (Adv. Math. Sci. Appl. 1999; 9:347–359). Uniform boundedness and blow-up of radial solutions are studied by Nagai and Sen
This paper deals with positive radially symmetric solutions of the Neumann boundary value problem for the fully parabolic chemotaxis system, {ut=Δu−∇⋅(u∇χ(v))in Ω×(0,∞),τvt=Δv−v+uin Ω×(0,∞), in a ball with general sensitivity function satisfying and decaying property (), parameter and nonnegative radially symmetric initial data.
This paper is concerned with the parabolic-elliptic Keller-Segel system with signal-dependent sensitivity $\chi(v)$,\begin{align*}\begin{cases}u_t=\Delta u - \nabla \cdot ( u \nabla \chi(v))&\mathrm{in}\ \Omega\times(0,\infty), \\0=\Delta v -v+u&\mathrm{in}\ \Omega\times(0,\infty),\end{cases}\end{align*}under homogeneous Neumann boundary condition in a smoothly bounded domain$\Omega \subset \mathbb{R}^2$with nonnegative initial data $u_0 \in C^{0}(\overline{\Omega})$, $\not\equiv 0$.  
This paper deals with time-global solutions to the parabolic system under the homogeneous Neumann boundary conditions in a bounded and convex domain () with smooth boundary . Here τ is a positive parameter, χ is a smooth function on satisfying and is a pair of nonnegative initial data.
Abstract This paper deals with classical solutions to the parabolic–parabolic system <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="block" overflow="scroll"> <mml:mfenced close="" open="{"> <mml:mrow> <mml:mtable class="cases" columnspacing="1"> <mml:mtr> <mml:mtd columnalign="left"> <mml:msub> <mml:mrow> <mml:mi>u</mml:mi> </mml:mrow> <mml:mrow> <mml:mi>t</mml:mi> </mml:mrow> </mml:msub> <mml:mo>=</mml:mo> <mml:mi mathvariant="normal">Δ</mml:mi> <mml:mrow> <mml:mo stretchy="f
Open papers in the app to read, cite, and organize with AI.