Sungkyunkwan University · Medicine
Professor Kyungdo Han's research lab specializes in epidemiological and population-based studies focusing on the interplay between lifestyle factors, metabolic diseases, and gastrointestinal and thyroid cancers. The lab investigates the impact of alcohol consumption patterns, nonalcoholic fatty liver disease (NAFLD), and metabolic phenotypes—such as lean or diabetic subtypes of MAFLD—on cancer incidence and mortality. Using large-scale national health insurance databases, the lab employs advanced statistical methods like Cox regression to identify modifiable risk factors and improve risk stratification in chronic disease outcomes. Their work emphasizes preventive medicine through early detection and targeted interventions in metabolic and gastrointestinal disorders.
Figures are computed from collected data and may differ slightly.
In this cohort study, frequent drinking was a more important risk factor for incident GI cancers than the amount of alcohol consumed per occasion. Individuals should be cautioned about regular consumption of small amounts of alcohol in addition to the total amount of alcohol consumption or amount per occasion.
We investigated the association between nonalcoholic fatty liver disease (NAFLD) and gastrointestinal tract cancer in the general population. Retrospective data on individuals aged ≥20 years who received healthcare checkups from January 1, 2009 to December 31, 2009 were analyzed using the National Health Insurance Database in Korea. NAFLD was defined based on the fatty liver index (FLI ≥60). The primary outcome was newly diagnosed esophageal, stomach, or colorectal cancer using ICD-10 codes duri
The MAFLD-lean and MAFLD-diabetes groups had a higher risk of all-cause and disease-specific mortality than did the MAFLD-overweight/obese group. Classifying MAFLD subgroups based on metabolic phenotypes might help risk stratification of patients with MAFLD.
<b><i>Background:</i></b> It is unclear if cigarette smoking and alcohol consumption are associated with thyroid cancer risk. Our aim was to explore for any associations between cigarette smoking and alcohol consumption with thyroid cancer, after adjusting for potential confounders. <b><i>Methods:</i></b> Using data from the Korean National Health Insurance database, we retrospectively identified individuals aged ≥20 years who participated in the 2009 health screening program and were followed u
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