Nagoya University · Medicine
Professor Masaaki Machino's research lab specializes in spinal cord disorders, with a primary focus on cervical spondylotic myelopathy and spinal cord injury without radiographic abnormality (SCIWORA). The lab investigates cervical spine alignment, range of motion, and spinal cord morphology using advanced medical imaging techniques such as MRI and multidetector-row CT myelography. Key research directions include understanding the impact of aging, diabetes, and degenerative changes on surgical outcomes, particularly in elderly patients undergoing cervical laminoplasty.
Figures are computed from collected data and may differ slightly.
Sagittal alignment was slightly changed, with only a 1.8° increase in lordosis. The ROM of the cervical spine was preserved by 87.9%. This preservation of alignment and ROM might be attributable to improvements including early removal of the cervical orthosis, postoperative neck exercises, and some surgical modifications.
Age-related and degenerative changes in the cervical spine, alignment, and ROM in each decade of life were established between CSM patients and asymptomatic subjects.
In Brief Study Design. This is a prospective imaging study of adult patients with cervical spinal cord injury without radiographic abnormality (SCIWORA). Objective. The purpose of this study was to investigate the occurrence rate of intramedullary high-signal intensity (increased signal intensity [ISI]) and prevertebral hyperintensity (PVH) in patients with SCIWORA, and examine their relationship to symptom severity and surgical outcome. Summary of Background Data. SCIWORA is accompanied by the
Diabetes with advanced age and long-term cervical spondylotic myelopathy symptoms adversely affected cervical laminoplasty outcomes. High preoperative glycated hemoglobin levels and long-term diabetes are risk factors for poor cervical laminoplasty outcomes in patients with diabetes and cervical spondylotic myelopathy.
Pre- and postoperative JOA scores were low in elderly patients. However, the achieved JOA score was almost similar among the 3 groups. Thus, elderly patients could obtain reasonable recovery after cervical laminoplasty.
In Brief The dural sac and spinal cord cross-sectional area during flexion and extension in patients with cervical spondylotic myelopathy were measured using multidetector-row computed tomography after myelography. The average dural sac and spinal cord cross-sectional area were less during extension than during fl exion from the C3–C4 to C7–T1 disc levels.
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TTIF provides for safe interbody fusion and 270 degrees of decompression using a single posterior approach. TTIF is a useful method for reconstructing thoracic spine lesions associated with neurologic deficits.
Modified double-door laminoplasty is a safe, reliable, and effective procedure for patients with CSM.
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The presence of PLC injury significantly influenced the severity of damage. In management of thoracic lumbar burst fractures, evaluation of PLC injury is important to accurately assess the severity of damage.
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