Kyushu University · Medicine
Professor Masanori Fujii's research lab specializes in orthopedic biomechanics and hip joint pathology, with a primary focus on developmental dysplasia of the hip (DDH). The lab investigates the morphological and structural abnormalities of the pelvis and acetabulum, emphasizing the role of acetabular retroversion and anterosuperior joint damage in early-onset osteoarthritis. Using clinical, radiological, and arthroscopic analyses, the lab explores the progression of intra-articular lesions and their impact on surgical outcomes, particularly following periacetabular osteotomy. Their work bridges clinical orthopedics with biomechanical principles to improve early diagnosis and long-term joint preservation strategies.
Figures are computed from collected data and may differ slightly.
In patients with developmental dysplasia of the hip, acetabular retroversion results from relatively deficient coverage by the posterior portion of the acetabulum. Developmental dysplasia with acetabular retroversion is associated with an earlier onset of pain than is developmental dysplasia with anteversion, suggesting a correlation between deficiency of the posterior acetabular wall and the earlier onset of pain.
Our observations suggest structural abnormalities exist throughout the pelvis in DDH, and the morphologic abnormalities of the acetabulum are not caused solely by local dysplasia around the hip, but are influenced by the morphologic features of the entire pelvis.
The incidence of intraarticular lesions in developmental dysplasia of the hip was high, even in the prearthritic stage. These lesions tended to originate in the anterosuperior area of the acetabulum and were generally progressive.
In order to clarify how intra-articular lesions influence the survival of a periacetabular osteotomy in patients with dysplasia of the hip, we performed an observational study of 121 patients (121 hips) who underwent a transposition osteotomy of the acetabulum combined with an arthroscopy. Their mean age was 40.2 years (13 to 64) and the mean follow-up was 9.9 years (2 to 18). Labral and cartilage degeneration tended to originate from the anterosuperior part of the acetabulum, followed by the fe
Level IV, diagnostic study. See the Guidelines for Authors for a complete description of levels of evidence.
Abstract Measurements of light scatting, sedimentation equilibrium, sedimentation velocity, and viscosity were carried out on fractions of native amylose in dimethylsulfoxide at 25°C. The data for statistical radius as a function of weight‐average molecular weight M w suggested a stiff nature of this biopolymer in the solvent studied when interpreted in terms of Kirste's recent calculations with a stiff chain model. The data for sedimentation coefficient were consistent with this suggestion, and
Level IV, diagnostic study.
Level III, diagnostic study.
<i>Objectives.</i> To determine the minimum lateral bone coverage required for securing stable fixation of the porous-coated acetabular components (cups) in hip dysplasia. <i>Methods.</i> In total, 215 primary total hip arthroplasties in 199 patients were reviewed. The average follow-up period was 49 months (range: 24-77 months). The lateral bone coverage of the cups was assessed by determining the cup center-edge (cup-CE) angle and the bone coverage index (BCI) from anteroposterior pelvic radio
Our findings suggest that TOA with structural bone allografting is a viable surgical option for correcting severely dysplastic acetabulum in adolescents and young adults without advanced osteoarthritis, with favourable mid-term outcomes.
Abstract Laser-induced desorption and ionization (LDI) of gold ions (Aun+: n = 1–3) were observed from gold nanorods in a liver tissue section (thickness: 10 µm). Larger amounts of gold nanorods produced stronger mass signals. Organic molecules in the tissue were not detected and did not inhibit the LDI processes of the gold nanorods in the tissue. Because of the selective LDI processes of the gold nanorods, the distribution of gold in the liver was successfully determined by imaging mass spectr
Level IV, therapeutic study.
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