Masaru Watanabe

Catalytic dehydration of fructose into 5-hydroxymethylfurfural by microwave heating was studied in acetone-water mixtures in the presence of a cation exchange resin catalyst. The use of acetone–water reaction media resulted in yields of 5-HMF as high as 73.4% for 94% conversion at 150 °C. It was confirmed that there was no decrease of catalytic activity and selectivity for five reuses of the resin, which was in accordance with the elemental analysis results that showed that sulfonic acid groups

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTChemical Reactions of C1 Compounds in Near-Critical and Supercritical WaterMasaru Watanabe*†, Takafumi Sato‡, Hiroshi Inomata*†, Richard Lee Smith Jr.†, Kunio Arai Jr.†, Andrea Kruse*§, and Eckhard Dinjus§View Author Information Research Center of Supercritical Fluid Technology, Tohoku University, 6-6-07 Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan, Department of Applied Chemistry, Utsunomiya University, 7-1-2 Yoto, Utsunomiya 321-8585, Japan, and Ins

The ultra-sensitive ddPCR assay revealed that pretreatment T790M was found in the majority of NSCLC patients with EGFR-activating mutations. ddPCR should be utilized for detailed assessment of the impact of the low frequency pretreatment T790M mutation on treatment with EGFR-TKIs.

In higher plants, an outer layer of meristematic cells, the protoderm, forms early in embryogenesis and this layer gives rise to the epidermis in differentiating tissues. We proposed previously that an Arabidopsis thaliana homolog of crinkly4 (ACR4), a gene for a receptor-like protein kinase, would be involved in differentiation and/or maintenance of epidermis-related tissues. In the present study, we isolated loss-of-function acr4 mutants by a reverse genetic approach. Our extensive analyses us