Tohoku University · Biochemistry, Genetics and Molecular Biology
Professor Masatake Kuroha's research lab specializes in gastrointestinal endoscopy and molecular diagnostics, focusing on the development of minimally invasive techniques and biomarkers for early detection of colorectal and gastrointestinal malignancies. The lab investigates exosomal microRNAs as potential diagnostic tools for colorectal adenoma (CRA), explores the impact of pretreatment biopsy on endoscopic submucosal dissection (ESD) outcomes, and examines rare gastrointestinal lymphomas using advanced endoscopic imaging. Their work bridges clinical endoscopy with molecular pathology to improve diagnostic accuracy and procedural efficiency.
Figures are computed from collected data and may differ slightly.
We found that exosomal miRNAs derived from the CRA organoid culture could be potential diagnostic biomarkers for CRA.
Pretreatment biopsy causes submucosal fibrosis resulting in prolonged procedure times and incomplete resection. These findings suggest important benefits of avoiding biopsy before ESD.
Follicular lymphoma (FL) of the gastrointestinal tract is a rare disease [1] [2]. We report a case of primary FL of the rectum, in which the characteristic endoscopic findings were observed in detail using magnifying endoscopy with narrow band imaging (NBI).
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