The University of Tokyo · Chemistry
모토무 카나이 교수의 연구실은 주로 비대칭 촉매화 및 다기능 촉매 시스템 개발에 초점을 맞추고 있습니다. 특히 BINOL 衍생 촉매와 당 유도체를 활용한 고엔anti오선택적 반응, 예를 들어 시아노실릴화 반응, Reissert 반응, 스티레커 반응 등에서 높은 입체선택성을 구현하는 데 성공했습니다. 또한 다가성 리간드의 길이가 단백질(Concanavalin A)과의 상호작용에 미치는 영향을 규명하는 생물화학적 응용 연구도 수행하고 있습니다. 이는 생체분자 인식과 관련된 새로운 촉매 및 재료 설계에 기여하고 있습니다.
Figures are computed from collected data and may differ slightly.
The concept of bifunctional asymmetric catalysis is very powerful for designing new enantioselective catalysts. We describe our investigation starting with the development of a BINOL-derived Lewis acid-Lewis base bifunctional asymmetric catalyst for cyanosilylation of aldehydes. The initial establishment of the concept was followed by the development of new sugar-derived catalysts that promote general catalytic enantioselective cyanosilylation of ketones. We also describe the catalytic enantiose
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTVarying the Size of Multivalent Ligands: The Dependence of Concanavalin A Binding on Neoglycopolymer LengthMotomu Kanai, Kathleen H. Mortell, and Laura L. KiesslingView Author Information Department of Chemistry University of WisconsinMadison Madison, Wisconsin 53706 Cite this: J. Am. Chem. Soc. 1997, 119, 41, 9931–9932Publication Date (Web):October 15, 1997Publication History Received24 June 1997Published online15 October 1997Published inissue 1
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