Sangwon Seo

Various scientific computations have become so complex, and thus computation tools play an important role. In this paper, we explore the state-of-the-art framework providing high-level matrix computation primitives with MapReduce through the case study approach, and demonstrate these primitives with different computation engines to show the performance and scalability. We believe the opportunity for using MapReduce in scientific computation is even more promising than the success to date in the

A decarboxylative radical cyclization reaction has been developed for the synthesis of fluorenones. The reaction uses Ag(I)/K2S2O8 to oxidatively decarboxylate an aroylbenzoic acid to an aryl radical, which undergoes cyclization to afford fluorenone products in good yield.

MapReduce is a programming model that supports distributed and parallel processing for large-scale data-intensive applications such as machine learning, data mining, and scientific simulation. Hadoop is an open-source implementation of the MapReduce programming model. Hadoop is used by many companies including Yahoo!, Amazon, and Facebook to perform various data mining on large-scale data sets such as user search logs and visit logs. In these cases, it is very common to share the same computing

A variety of heteroarenes and electron rich arenes can be trifluoromethylated at room temperature with TMSCF3, catalytic silver and PhI(OAc)2.

A new approach to protodecarboxylation is described that enhances the substrate scope for benzoic acids. The reaction uses oxidative radical conditions to decarboxylate a variety of acids in acetonitrile.

The formal hydroamination/hydroamidation utilizing metal hydride is an appealing synthetic tool for the construction of valuable nitrogen-containing compounds from unsaturated hydrocarbons. While significant advances have been made for the functionalizations of alkenes in this realm, the direct hydroamidation of alkynes remains rather limited due to the high feasibility of the key metal-alkenyl intermediate to choose other reaction pathways. Herein, we report a NiH-catalyzed strategy for the hyd

Intramolecular alkyne hydroamidation represents a straightforward approach for the access to synthetically valuable cyclic enamides. Despite some advances made in this realm, the ability to attain a precise regiocontrol still remains challenging, especially for <i>endo</i> cyclization that leads to six-membered and larger azacyclic rings. Herein, we report a NiH-catalyzed intramolecular hydroamidation of alkynyl dioxazolones that allows for an excellent <i>endo</i> selectivity, thus affording a

These results suggest that the expression of iNOS mRNA is upregulated by UVB irradiation, and that NO produced by this inducible enzyme may play a part as a mediator or an immunomodulator in UV-induced skin reactions such as sunburn reaction and photo-induced immune alterations.

Near-threshold operation has emerged as a competitive approach for energy-efficient architecture design. In particular, a combination of near-threshold circuit techniques and parallel SIMD computations achieves excellent energy efficiency for easy-to-parallelize applications. However, near-threshold operations suffer from delay variations due to increased process variability. This is exacerbated in wide SIMD architectures where the number of critical paths are multiplied by the SIMD width. This

Herein, we report a polar-radical relay strategy for α-C-H amination of cyclic amines with N-chloro-N-sodio-carbamates. The relay is initiated by in situ generation of cyclic iminium intermediate using N-iodosuccinimide (NIS) oxidant as an initiator, which then operates through a series of polar (addition and elimination) and radical (homolysis, hydrogen- and halogen atom transfer) reactions to enable the challenging C-N bond formation in a controlled manner. A broad range of α-amino cyclic amin

Herein, we report a photoinduced transition-metal-free C(aryl)-N bond formation between 2,4,6-tri(aryl)boroxines or arylboronic acids as an aryl source and 1,4,2-dioxazol-5-ones (dioxazolones) as an amide coupling partner. Chloride anion, either generated <i>in situ</i> by photodissociation of chlorinated solvent molecules or added separately as an additive, was found to play a critical cooperative role, thereby giving convenient access to a wide range of synthetically versatile <i>N</i>-arylami

Low Density Parity Check (LDPC) codes are one of the most promising error correction codes that are being adopted by many wireless standards. This paper presents a case study for a scalable LDPC decoder supporting multiple code rates and multiple block sizes on a software defined radio (SDR) platform. Since technology scaling alone is not sufficient for current SDR architectures to meet the requirements of the next generation wireless standards, this paper presents three techniques to improve th

A highly efficient Cu(I)-catalyzed addition/annulation sequence has been developed for the synthesis of (Z)-ylidenebutenolides employing readily available α-ketoacids and alkynes as substrates. The reactions employ a simple commercially available Cu(I)-catalyst, display good substrate scope, and deliver products with high stereoselectivity. The synthetic utility of the method is demonstrated by the straightforward derivatization of the ylidenebutenolides into a diverse range of heterocycles, and