Shigenobu Koseki

Professor Shigenobu Koseki's research lab specializes in food safety and microbial risk assessment, focusing on the behavior of pathogenic bacteria in the gastrointestinal environment. The lab develops mathematical models to predict bacterial inactivation kinetics under varying gastric conditions, particularly in response to pH changes during digestion. Key research directions include understanding dose-response relationships for foodborne pathogens such as *Listeria monocytogenes*, *Escherichia coli* O157:H7, and *Salmonella* spp., using advanced kinetic models like the Weibull and modified logistic equations. The lab also investigates the impact of environmental factors on bacterial survival to improve food safety risk assessment and intervention strategies.