The University of Osaka · Medicine
Professor Shingo Ohira's research lab specializes in advanced radiation therapy techniques, with a focus on stereotactic radiosurgery (SRS) and volumetric modulated arc therapy (VMAT) for intracranial and extracranial targets. The lab investigates image-guided radiotherapy, immobilization devices, and multileaf collimator (MLC) design to enhance treatment precision, dose conformity, and normal tissue sparing. Key research directions include optimizing HyperArc and HA-VMAT delivery, minimizing setup errors, and validating Monte Carlo-based dose calculation models for accurate treatment planning.
Figures are computed from collected data and may differ slightly.
HA-VMAT plans provided significantly higher conformity and rapid dose falloff with respect to the C-VMAT plans.
The rotational setup errors for multiple brain metastases cases caused non-negligible underdosage for PTV and significant increases of V<sub>10Gy</sub> to V<sub>16Gy</sub> in SRS with HyperArc.
Encompass provided patient immobilization with adequate accuracy during HA treatment. The absolute maximum displacement IM was less than IM<sub>NC</sub> along the translational/rotational axes, and no statistically significant relationship between the treatment time and the IM was observed.
The narrower MLC provided significantly higher conformity, steeper dose gradient, and better normal tissue sparing.
The IME during STI using open- and full-face clamshell-style immobilization devices is approximately equal considering the adequate accuracy in patient positioning.
Our findings demonstrate the accuracy of the MC model using an adapted BEAMnrc component module for the Agility MLC.
Overall, the accuracy of iodine and HU values was higher for DLCT than for FKSCT.
The WDI estimated the RED and MD accurately and could form the basis for a new treatment planning approach for pancreatic cancer using contrast-enhancing agent.
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