The University of Tokyo · Medicine
Fujita 교수의 연구실은 뇌와 간을 중심으로 한 고해상도 다중 매개변수 자기공명영상(MRI) 기법 개발에 주력하고 있습니다. 특히 뇌의 구조적 변화와 간의 질환 평가를 위한 정량적 MRI 기술, 예를 들어 영상학적 맵핑(Magnetic Resonance Fingerprinting, MRF)을 활용해 빠르고 정밀한 진단 방법을 개발하고 있습니다. 연구는 임상 적용 가능성을 고려한 반복성, 정확성 및 조직병리학적 검증을 기반으로 진행되고 있습니다.
Figures are computed from collected data and may differ slightly.
In this cohort study of adults without dementia, age-dependent brain structure volumes and volume change rates in various brain structures were characterized using serial magnetic resonance imaging scans. These findings clarified the normal distributions in the aging brain, which are essential for understanding the process of age-related neurodegenerative diseases.
Three-dimensional synthetic MR imaging could serve as an alternative to conventional MR imaging in evaluating MS with a reduced scan time.
Three-dimensional (3D) Magnetic resonance fingerprinting (MRF) permits whole-brain volumetric quantification of T1 and T2 relaxation values, potentially replacing conventional T1-weighted structural imaging for common brain imaging analysis. The aim of this study was to evaluate the repeatability and reproducibility of 3D MRF in evaluating brain cortical thickness and subcortical volumetric analysis in healthy volunteers using conventional 3D T1-weighted images as a reference standard. Scan-resc
Background Liver MR fingerprinting (MRF) enables simultaneous quantification of T1, T2, T2*, and proton density fat fraction (PDFF) maps in single breath-hold acquisitions. Histopathologic correlation studies are desired for its clinical use. Purpose To compare liver MRF-derived metrics with separate reference quantitative MRI in participants with diffuse liver disease, evaluate scan-rescan repeatability of liver MRF, and validate MRF-derived measurements for histologic grading of liver biopsies
With the recent advancements in rapid imaging methods, higher numbers of contrasts and quantitative parameters can be acquired in less and less time. Some acquisition models simultaneously obtain multiparametric images and quantitative maps to reduce scan times and avoid potential issues associated with the registration of different images. Multiparametric magnetic resonance imaging (MRI) has the potential to provide complementary information on a target lesion and thus overcome the limitations
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