Korea University · Engineering
Professor Sungkyu Seo's research lab specializes in advanced nanofabrication and optoelectronic characterization techniques, focusing on lens-free holographic imaging, plasmonic nanostructures, and quantum dot-based nanolithography. The lab develops innovative on-chip cytometry platforms for high-throughput biomedical analysis, including automated cell counting and hemoglobin concentration measurement, while also pioneering novel photolithography methods using quantum dots for high-precision nanoscale patterning. Their work bridges nanophotonics, biomedicine, and materials science, emphasizing low-cost, high-resolution imaging and scalable nanofabrication. The lab's research is centered on creating next-generation tools for point-of-care diagnostics and functional nanomaterials.
Figures are computed from collected data and may differ slightly.
We experimentally illustrate a lensfree holographic imaging platform to perform on-chip cytometry. By controlling the spatial coherence of the illumination source, we record a 2D holographic diffraction pattern of each cell or micro-particle on a chip using a high resolution sensor array that has approximately 2 microm pixel size. The recorded holographic image is then processed by using a custom developed decision algorithm for matching the detected hologram texture to existing library images f
We present a detailed investigation of the performance of lens-free holographic microscopy toward high-throughput on-chip blood analysis. Using a spatially incoherent source that is emanating from a large aperture, automated counting of red blood cells with minimal sample preparation steps at densities reaching up to approximately 0.4 x 10(6) cells/muL is presented. Using the same lens-free holographic microscopy platform, we also characterize the volume of the red blood cells at the single-cell
Quantum dots (QDs) have emerged as an important class of materials for diverse applications such as solid-state lighting, energy conversion, displays, biomedicine, and plasmonics due to their excellent photonic properties and durability. Soft lithography, inkjet printing, nanoimprinting, and polymer deep-pen lithography are primary lithography techniques employed to implement micro-patterns with QDs, however, there are limited reports on QD photolithography using conventional photolithography pr
This article presents a novel device, the plasmonic lens (PL), consisting of equally spaced ring apertures in a metal film deposited on a fused silica substrate. It was fabricated by electron-beam lithography (EBL) and reactive-ion etching (RIE). When illuminated by a collimated laser, a cylindrical surface plasmon (SP) is excited in the PL, scattered by the structure, and propagates. As a result, the PL focuses a subwavelength spot in the midfield, i.e., the focal length is several microns. The
The lens-free shadow imaging technique (LSIT) is a well-established technique for the characterization of microparticles and biological cells. Due to its simplicity and cost-effectiveness, various low-cost solutions have been developed, such as automatic analysis of complete blood count (CBC), cell viability, 2D cell morphology, 3D cell tomography, etc. The developed auto characterization algorithm so far for this custom-developed LSIT cytometer was based on the handcrafted features of the cell
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