The University of Tokyo · Environmental Science
Professor Yoonhee Kim's research lab focuses on environmental health and climate-related health impacts, with a strong emphasis on the effects of extreme temperatures and air pollution on mental health outcomes such as suicide. The lab conducts epidemiological and environmental modeling studies to understand the relationships between climate variables—like ambient temperature and precipitation—and public health risks, particularly in vulnerable populations. They also develop predictive models for climate-sensitive diseases, such as malaria, using long-term meteorological and disease surveillance data. Their work integrates environmental science, public health, and hydrological modeling to support early warning systems and health policy interventions.
Figures are computed from collected data and may differ slightly.
Twenty-five years ago the first small molecule inhibitors of Hsp90 were identified. In the intervening years there has been dramatic progress in basic scientific understanding of the Hsp90 chaperone machinery and in the role of Hsp90 in malignancy. The first-in-class Hsp90 inhibitor 17-AAG entered into Phase I clinical trials in 1999. There are now 13 Hsp90 inhibitors in clinical trial, representing multiple drug classes, and hundreds of patients have been treated in adult oncology and pediatric
Our findings showed that the risk of suicide increased with increasing ambient temperature in many countries, but to varying extents and not necessarily linearly. This temperature-suicide association should be interpreted cautiously, and further evidence of the relationship and modifying factors is needed. https://doi.org/10.1289/EHP4898.
Kim Y, Kim H, Honda Y, Guo YL, Chen BY, Woo JM, Ebi KL. 2016. Suicide and ambient temperature in East Asian countries: a time-stratified case-crossover analysis. Environ Health Perspect 124:75-80; http://dx.doi.org/10.1289/ehp.1409392.
Our findings suggest that higher levels of air pollution may be associated with suicide, and further research is merited to understand the underlying mechanisms. https://doi.org/10.1289/EHP2223.
Although there have been enormous demands and efforts to develop an early warning system for malaria, no sustainable system has remained. Well-organized malaria surveillance and high-quality climate forecasts are required to sustain a malaria early warning system in conjunction with an effective malaria prediction model. We aimed to develop a weather-based malaria prediction model using a weekly time-series data including temperature, precipitation, and malaria cases from 1998 to 2015 in Vhembe,
Abstract The temporal and spatial distribution of water temperature was surveyed and simulated in a deep warm monomictic reservoir (Lake Soyang, Korea). The great depth (maximum depth 118 m) and wind-sheltered dendritic shape caused stable thermal stratification in summer. Turbid storm runoff during the summer monsoon formed a 20–40 m intermediate layer distinct from the clearer epilimnion and hypolimnion. The temperature distribution and movements of the density current were simulated by using
Despite impressive economic growth and increasing prosperity, cities in Mexico do not seem to have fully captured the benefits of urban agglomeration, in part because of rapid and uncoordinated urban growth. Recent expansion of many Mexican cities has been distant, disconnected, and dispersed, driven mainly by large single-use housing developments on the outskirts of cities. The lack of a coordinated approach to urban development has hindered the ability of cities in Mexico to boost economic gro
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