Yoshiyuki Takahashi

Transplanted donor lymphocytes infused during hematopoietic stem cell transplantation (HSCT) have been shown to cure patients with hematological malignancies. However, less is known about the effects of HSCT on metastatic solid tumors. Thus, a better understanding of the immune cells and their target antigens that mediate tumor regression is urgently needed to develop more effective HSCT approaches for solid tumors. Here we report regression of metastatic renal cell carcinoma (RCC) in patients f

During the preparation of the manuscript, the definition of the error bars was inadvertently omitted. In all figures, error bars indicate SEM.

JEM-EUSO is a space science mission to explore extreme energies and physics of the Universe. Its instrument will watch the dark-side of the earth and will detect UV photons emitted from the extensive air shower caused by an Ultra-High Energy Cosmic Rays (UHECRs above 10^18 eV), or Extremely High Energy Cosmic Ray (EHECR) particle (e.g., above about 10^20 eV). Such a high-rigidity particles as the latter arrives almost in a straight-line from its origin through the magnetic fields of our Milky Wa

We examined the relationship among morphological appearance (six groups) of bovine oocytes, ATP content and maturational/developmental ability. Oocytes with a brown ooplasm (with or without a dark region) had intermediate levels of ATP at the germinal vesicle (GV) stage and showed higher rates of first polar body (PB) extrusion than the other groups. Oocytes with a low level of ATP (oocytes with a pale ooplasm without dark clusters) and oocytes with a high level of ATP (oocytes with a black oopl