Seoul National University · Medicine
Professor You Hwan Jo's research lab specializes in critical care medicine and emergency medicine, with a focus on improving early detection and management of severe sepsis and critical illness. The lab investigates biomarkers such as monocyte counts and develops predictive scoring systems—like DEWS—to enhance risk stratification and timely intervention in high-acuity patients. Another key area of research involves optimizing sedation strategies in pediatric intensive care, particularly comparing nitrous oxide and ketamine for safety and efficacy. The lab's work aims to translate clinical data into practical tools that improve patient outcomes in emergency and critical care settings.
Figures are computed from collected data and may differ slightly.
This study was performed to evaluate the association of monocyte counts with mortality, the rate of bacteremia, and organ dysfunction and to evaluate whether the change in monocyte counts from the premorbid state to sepsis would differ between survivors and non-survivors in patients with severe sepsis including septic shock. A retrospective analysis of patients with severe sepsis including septic shock was performed. Monocyte counts were categorized into <250, 250-500, 500-750, and ≥750 cells/μL
Our study showed that DEWS was superior to MEWS in three key aspects (IHCA predictive, alarming, and timeliness performance). This study demonstrates the potential of DEWS as an effective, efficient screening tool in rapid response systems (RRSs) to identify high-risk patients.
Nitrous oxide inhalation was preferable to injectable ketamine for pediatric patients because it is safe, allows for a faster recovery, maintains sufficient sedation time, and does not induce unnecessarily deep sedation.
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