Yonsei University · Medicine
Professor Young Dae Kim's research lab focuses on cerebrovascular and cardiovascular diseases, particularly the interplay between metabolic disorders such as NAFLD and sarcopenia with stroke and atherosclerotic cardiovascular disease (ASCVD). The lab investigates vascular risk factors, early intervention strategies in stroke, and the role of clinical scores like CHADS2 in predicting cerebrovascular pathology. A key emphasis is placed on understanding disease progression in aging and urbanized populations, especially in East Asian countries, and optimizing treatment protocols for acute conditions like variceal bleeding in liver cirrhosis.
Figures are computed from collected data and may differ slightly.
NAFLD and sarcopenia were significantly associated with an increased risk of ASCVD in the general population. In addition, NAFLD with significant liver fibrosis and sarcopenia were significantly associated with an increased risk of ASCVD in subjects with NAFLD.
Early administration of tPA after stroke onset is associated with better thrombus resolution.
The CHADS(2) score can predict the presence of concomitant cerebral artery atherosclerosis. Increased risk of stroke in patients with high CHADS(2) scores may be partly explained by increased frequency and burden of cerebral atherosclerosis.
Stroke is one of the leading causes of death and morbidity worldwide. The occurrence of stroke is strongly dependent on well-known vascular risk factors. After rapid modernization, urbanization, and mechanization, East Asian countries have experienced growth in their aged populations, as well as changes in lifestyle and diet. This phenomenon has increased the prevalence of vascular risk factors among Asian populations, which are susceptible to developing cardiovascular risk factors. However, dif
Our results suggest that seizure freedom without aura at >or=1 year is a reasonable indication for the attempt at AED discontinuation. The subsequent control of recurrent seizures was excellent, especially if seizures relapsed after the complete discontinuation of AEDs. Younger age at the time of surgery and a shorter disease duration seem to affect successful AED discontinuation for a long-term period.
Acute variceal bleeding could be a fatal complication in patients with liver cirrhosis. In patients with decompensated liver cirrhosis accompanied by ascites or hepatic encephalopathy, acute variceal bleeding is associated with a high mortality rate. Therefore, timely endoscopic hemostasis and prevention of relapse of bleeding are most important. The treatment goals for acute variceal bleeding are to correct hypovolemia; achieve rapid hemostasis; and prevent early rebleeding, complications relat
Considering the positive association between the presence of CMBs and OA-related ICH, our results suggest that the increase in ICH in high-risk groups during OA may be related to an increased burden of CMBs.
The dependence of multifragment-emission processes upon linear momentum transfer to the target residue is determined for $^{36}\mathrm{induced}$ reactions on $^{238}\mathrm{U}$ at E/A=35 MeV. Significantly more intermediate-mass fragments are emitted in central collisions. Multiplicity distributions for intermediate-mass fragments emitted behind the grazing angle resemble Poisson distributions and are consistent with a stochastic production process. Exit channels with up to five intermediate-mas
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