Young Keun Kim

Abstract Integrated circuits (ICs) are challenged to deliver historically anticipated performance improvements while increasing the cost and complexity of the technology with each generation. Front‐end‐of‐line (FEOL) processes have provided various solutions to this predicament, whereas the back‐end‐of‐line (BEOL) processes have taken a step back. With continuous IC scaling, the speed of the entire chip has reached a point where its performance is determined by the performance of the interconnec

We present a novel method of radio frequency (RF)-mediated thermotherapy in tumors by remotely heating nickel (Ni)-gold (Au) core-shell nanowires (CSNWs). Ectopic pancreatic tumors were developed in nude mice to evaluate the thermotherapeutic effects on tumor progression. Tumor ablation was produced by RF-mediated thermotherapy via activation of the paramagnetic properties of the Ni-Au CSNWs. Histopathology demonstrated that heat generated by RF irradiation caused significant cellular death with

Engineering and application of nanomaterials have recently helped advance various biomedical fields. Zinc oxide (ZnO)-based nanocomposites have become one of the most promising candidates for biomedical applications due to their biocompatibility, unique physicochemical properties, and cost-effective mass production. In addition, recent advances in nano-engineering technologies enable the generation of ZnO nanocomposites with unique three-dimensional structures and surface characteristics that ar

Native extracellular matrix (ECM) exhibits dynamic change in the ligand position. Herein, the ECM-emulating control and real-time monitoring of stem cell differentiation are demonstrated by ligand nanoassembly. The density of gold nanoassembly presenting cell-adhesive Arg-Gly-Asp (RGD) ligand on Fe₃ O₄ (magnetite) nanoparticle in nanostructures flexibly grafted to material is changed while keeping macroscale ligand density invariant. The ligand nanoassembly on the Fe<sub>3<

The native extracellular matrix (ECM) can exhibit heterogeneous nano-sequences periodically displaying ligands to regulate complex cell-material interactions in vivo. Herein, an ECM-emulating heterogeneous barcoding system, including ligand-bearing Au and ligand-free Fe nano-segments, is developed to independently present tunable frequency and sequences in nano-segments of cell-adhesive RGD ligand. Specifically, similar exposed surface areas of total Fe and Au nano-segments are designed. Fe segm

Cell adhesion occurs when integrin recognizes and binds to Arg-Gly-Asp (RGD) ligands present in fibronectin. In this work, submolecular ligand size and spacing are tuned via template-mediated in situ growth of nanoparticles for dynamic macrophage modulation. To tune liganded gold nanoparticle (GNP) size and spacing from 3 to 20 nm, in situ localized assemblies of GNP arrays on nanomagnetite templates are engineered. 3 nm-spaced ligands stimulate the binding of integrin, which mediates macrophage

MnO _x-based catalysts have been applied to the selective catalytic reduction of NO _x with ammonia (NH₃) owing to their high NO _x removal efficiency and catalytic stability. In general, the fabrication of a variety of nanomaterials in a complex structure requires complicated processes, including heat treatment and a series of cleaning steps. In addition, MnO₂ which has diverse polymorphs, exhibits different catalytic effects depending on its

We report annealing time effects on the microstructural evolution and resultant magneto-transport property changes in Ta/NiFe/CoFe/Cu/CoFe/PtMn/Ta spin valves comprising PtMn layer thicknesses ranging from 10 to 30 nm. Postdeposition annealing was performed at 270 °C up to 35 h. The blocking temperatures of samples with 20 nm PtMn and 30 nm PtMn layers were found to be 350 °C and 400 °C, respectively. The magnetoresistance and interlayer coupling field changes became large as annealing time incr

Abstract Cellular adhesion is regulated by the binding of 10 nm sized integrin to Arg‐Gly‐Asp (RGD) ligands present in extracellular matrix proteins. In this study, seed‐mediated growth of gold nanoparticles (AuNPs) on the surface of iron oxide (Fe 3 O 4 ) nanotemplates is employed to tune the diameter and interdistance of RGD‐bearing AuNPs at the receptor‐level. The Fe 3 O 4 nanotemplates decorated with RGD‐bearing AuNPs arranged in various RGD diameters and interdistances at the receptor‐level

Magnetic multi-granule nanoclusters (MGNCs) were easily formed by the simple reaction of FeCl3 in ethylene glycol, which served as both the solvent and reductant, in the presence of sodium acetate. Simple refluxing within glassware at atmospheric pressure allowed us to monitor changes in the color of reaction mixtures and isolate intermediates to be characterized. On the basis of these observations, we could suggest a new mechanism of solid-state phase transformation after the hydrolysis/condens

Fluorescent and magnetic Fe3O4@coordination polymer (Fe3O4@CP) nanochains are synthesized via a simple one-pot solvothermal reaction of magnetite (Fe3O4) and coordination polymer precursors in the presence of an external magnetic field. The shell thickness within Fe3O4@CPs was easily regulated by varying the amounts of coordination polymer precursors used during the reaction.