Kyoto University · Engineering
Professor Yuichi Ogawa's research lab specializes in advanced terahertz spectroscopy and label-free biosensing, focusing on the development of highly sensitive detection methods for biological molecules. The lab pioneers innovative techniques that combine terahertz time-domain spectroscopy with interference effects to enable real-time, non-invasive protein detection on flexible polymer membranes. Their work emphasizes applications in medical diagnostics and life science research, particularly for low-concentration biomolecular analysis. The lab also explores functional surface modifications using polymers like polyethylene glycol to enhance detection stability and specificity.
Figures are computed from collected data and may differ slightly.
We demonstrate a highly sensitive imaging method combined a terahertz time-domain spectroscopy and an interference effect for label-free protein detection on a polyvinylidene difluoride membrane. The method is based on terahertz time-domain spectroscopy and uses an interference effect. Biotin is linked to the membrane using poly ethylene glycol or poly ethylene glycol methyl ether to prevent it from being washed off. Binding of the biotin with streptavidin is then observed by measuring the terah
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