东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Miharu Nakanishi's research lab focuses on improving person-centered care for older adults with dementia and mental health conditions, with an emphasis on palliative care integration, trauma-informed approaches in mental health services, and non-pharmacological interventions to reduce restrictive practices. The lab investigates national dementia strategies, care delivery in acute and community settings, and the psychosocial impacts of crises such as the COVID-19 pandemic on vulnerable populations, including adolescent caregivers. A key direction is evaluating the effectiveness of training programmes and care models to enhance staff attitudes and clinical outcomes.
Professor Tsuyoshi Hirota's research lab specializes in circadian biology, focusing on the molecular mechanisms underlying the mammalian circadian clock and its role in health and disease. The lab employs chemical biology and high-throughput screening approaches to identify small molecules that modulate core clock components, particularly targeting proteins such as cryptochrome (CRY) and casein kinase 2 (CK2). By combining phenotypic screening, chemical probes, and systems-level modeling, the lab aims to dissect clock regulation and develop novel therapeutics for circadian-related disorders, including metabolic diseases and cancer. Their work also explores how metabolic cues like glucose entrain peripheral circadian clocks, revealing key links between metabolism and timekeeping at the cellular level.
Professor M. Shiro's research lab specializes in virology and molecular diagnostics, with a primary focus on avian herpesviruses, particularly Marek's disease virus (MDV). The lab develops sensitive and non-invasive molecular detection methods, such as nested PCR using feather tip-derived DNA, to differentiate highly virulent MDV strains from attenuated vaccine strains like CVI988. Their work emphasizes the identification of viral oncogenes, such as the meq gene, to improve disease surveillance and vaccine safety monitoring in poultry. The lab also contributes to the understanding of viral replication and pathogenesis in chickens through molecular virology and genetic analysis.
Professor Atsushi Shimojima's research lab specializes in the molecular design and synthesis of ordered inorganic-organic hybrid materials, with a focus on nanostructured siloxane-based systems. The lab explores self-assembly mechanisms of amphiphilic silicon-based precursors to create highly ordered mesostructures, including lamellar, hexagonal, and monoclinic phases, using sol-gel processes without traditional structure-directing agents. Key research directions include controlling interfacial structures at the molecular level, developing transparent and oriented thin films, and modifying layered silicates through silylation for tailored nanoarchitecture and functionality. The work integrates advanced characterization techniques such as XRD, NMR, and SEM to understand structure-property relationships in hybrid materials.
Professor Tomoyuki Takabatake's research lab specializes in coastal hazard mitigation, with a primary focus on tsunami and storm surge dynamics, particularly those generated by landslides and extreme weather events. The lab conducts integrated field surveys, laboratory experiments, and numerical simulations to understand tsunami propagation, inundation behavior, and human evacuation responses. Key research directions include landslide-generated tsunamis—especially partially submerged and subaerial types—and the development of predictive models and evacuation optimization strategies using advanced computational techniques such as agent-based modeling and reinforcement learning. The lab also investigates the influence of coastal urban structures on tsunami flow and the effectiveness of community-level disaster preparedness and awareness.
Professor Dai Yamazaki's research lab specializes in advancing global hydrological and geospatial modeling through high-resolution Earth observation data and innovative algorithm development. The lab focuses on creating accurate digital elevation models, global river routing systems, and hydrographic databases to improve the simulation of surface water dynamics, floodplain inundation, and river network structures. Key research directions include subgrid-scale topographic parameterization, automated extraction of river networks from satellite data, and computational efficiency in large-scale hydrological modeling. Their work bridges remote sensing, hydrology, and computational science to support climate, water resources, and environmental change studies.
Professor Shin Kajita's research lab specializes in plasma-material interactions, particularly focusing on the effects of helium ion irradiation on refractory metals like tungsten and molybdenum. The lab investigates the formation mechanisms of nanostructured surfaces—such as fiberform (fuzz) structures—driven by helium bubble nucleation and self-growth processes under fusion-relevant conditions. Their work explores both the detrimental impacts of these nanostructures on fusion reactor materials and their potential applications in advanced energy systems, such as solar thermophotovoltaics. The lab also studies transient thermal loads and unipolar arc phenomena induced by laser irradiation, simulating real-time disruptions in fusion devices like ITER.
Professor Tetsuo Ushiku's research lab specializes in molecular and pathological characterization of gastrointestinal and germ cell neoplasms, with a focus on identifying novel diagnostic biomarkers and understanding the molecular pathogenesis of gastric carcinoma, particularly subtypes associated with specific proteins like GPC3, p73, and claudin-6. The lab investigates the role of viral infections—such as Epstein-Barr virus—in gastric carcinogenesis and explores epigenetic alterations, including DNA methylation, in tumor suppressor genes. Additionally, the lab contributes to the histopathological classification of rare gastrointestinal tumors, such as extra-ampullary duodenal adenocarcinomas and inflammatory conditions like focally enhanced gastritis in pediatric IBD.
Professor Yuji Ikegaya's research lab specializes in cellular and systems neuroscience, focusing on the mechanisms of neural circuit dynamics, synaptic transmission, and plasticity in the mammalian brain. Using advanced imaging techniques such as in vivo and in vitro calcium imaging, whole-cell recordings, and high-speed multineuron imaging, the lab investigates how precise spatiotemporal patterns of synaptic activity give rise to neuronal computation and network function. A central theme is the role of dendritic integration, synaptic clustering, and stochastic connectivity in enabling reliable information processing despite synaptic noise. The lab also explores the molecular mechanisms underlying synaptic plasticity, particularly the involvement of phospholipase A2 and lipid mediators in long-term potentiation.
Professor Huilong Yang's research lab specializes in the development and characterization of advanced metallic materials, with a focus on zirconium-based alloys and their interfacial behavior in high-temperature applications. The lab investigates alloying effects, solid-state diffusion bonding, and intermetallic phase formation to enhance mechanical properties and microstructural stability. Key research directions include solid-solution and precipitation strengthening mechanisms, interfacial diffusion kinetics, and the role of elemental additions (e.g., Mo, Cr, Nb) in grain refinement and phase control. The lab employs advanced characterization techniques such as electron backscatter diffraction, transmission electron microscopy, and tensile testing to correlate microstructure with mechanical performance.
Professor Yu Yamashita's research lab focuses on the design, synthesis, and application of advanced organic semiconductors, particularly conjugated polymers and single crystals, for next-generation flexible and printed electronics. The lab specializes in controlling molecular and nano-scale ordering to achieve high charge carrier mobility and efficient electrical doping, with a strong emphasis on band-like transport and ion-exchange doping strategies. Key research directions include molecular doping mechanisms, structural control of polymer thin films, and the development of high-performance, air-stable organic field-effect transistors and strain sensors. The lab combines advanced characterization techniques with computational simulations to understand and optimize charge transport in complex soft materials.
Professor Masamune Oguri's research lab specializes in theoretical and observational astrophysics, with a primary focus on gravitational lensing, galaxy clusters, and dark matter. The lab investigates the mass distribution of galaxy clusters using strong and weak lensing techniques, develops advanced algorithms for cluster detection in large-scale surveys, and explores the implications of lensing for probing dark matter and distant high-redshift sources such as quasars and binary black hole mergers. Their work bridges theoretical modeling with cutting-edge observational data from major surveys like the Sloan Digital Sky Survey and upcoming synoptic surveys.
Professor Sridhara Nayak's research lab focuses on climate change impacts, particularly extreme weather events such as intense precipitation and typhoons, under changing climatic conditions. The lab employs regional climate modeling, downscaling techniques, and reanalysis data to investigate the influence of global warming on hydrological extremes, land-use changes, and atmospheric dynamics. Key research directions include the Clausius-Clapeyron relationship in extreme rainfall, typhoon intensification under pseudo-global warming, and regional climate variability in South Asia and Japan.
Professor Kosuke Namekata's research lab specializes in stellar astrophysics, focusing on the magnetic activity and energetic phenomena of solar-type stars, particularly superflares and their connection to stellar dynamo processes. The lab investigates the physical mechanisms behind stellar flares, filament eruptions, and coronal mass ejections using multiwavelength observations from space telescopes and ground-based facilities. A central theme is understanding the similarities and differences between solar and stellar flares to shed light on the evolution of space weather and its impact on planetary systems. The lab also studies the temporal evolution of starspots and their role in modulating stellar activity and flare occurrence.
Professor Riki Toita's research lab specializes in biomaterials and regenerative medicine, focusing on engineering smart materials that modulate immune responses and enhance tissue integration. The lab develops functionalized implants—such as titanium and poly(ether ether ketone) (PEEK) surfaces—engineered to promote osteoconduction and guide macrophage polarization toward pro-healing phenotypes. A key research direction involves designing protein-based nanocarriers and apoptotic cell mimetics for targeted delivery in cancer therapy and tissue repair. The lab also investigates host-material interactions, particularly in bone regeneration and hepatocellular carcinoma treatment, using advanced biomaterials and molecular engineering strategies.
Professor Mei-Fang Chien's research lab specializes in environmental biotechnology, focusing on microbial and plant-based remediation of heavy metal and metalloid pollutants such as cadmium, zinc, mercury, and arsenic. The lab investigates the molecular mechanisms of metal hyperaccumulation in plants like *Arabidopsis halleri* and *Pteris* ferns, as well as the role of microbial communities and transposons in enhancing metal resistance and bioremediation efficiency. A key research direction involves understanding how environmental factors—particularly temperature—affect metal uptake and translocation in hyperaccumulator species, aiming to optimize phytoremediation strategies under real-world conditions. The lab also explores microbial-assisted phytoextraction and the genetic basis of metal transport and detoxification in both plants and bacteria.
Professor Tadaki Suzuki's research lab focuses on viral pathogenesis and host-pathogen interactions, particularly involving human polyomaviruses and emerging viral infections such as SFTS and influenza. The lab investigates the molecular mechanisms of viral proteins—such as agnoprotein in JC virus and viroporins in other viruses—through structural virology, host protein interaction studies, and advanced imaging techniques like high-speed atomic force microscopy. Key research directions include understanding viral membrane modulation, identifying host factors involved in viral replication and spread, and elucidating the cellular targets and pathogenic mechanisms of lethal viruses in human tissues. The lab integrates structural biology, cell biology, and virology to uncover novel therapeutic targets for persistent and emerging viral diseases.
Professor Marthias Silwamba's research lab specializes in sustainable metallurgy and environmental remediation, focusing on the recovery of critical and hazardous metals from secondary sources such as industrial residues, contaminated soils, and electronic waste. The lab develops innovative hydrometallurgical techniques—particularly concurrent leaching and cementation using zero-valent metals like aluminum and iron—to simultaneously extract and stabilize valuable or toxic metals such as lead, zinc, gallium, germanium, and indium. A key emphasis is placed on designing environmentally benign, resource-efficient processes that enable metal recovery while minimizing environmental impact, often integrating magnetic separation for efficient solid-liquid separation. The lab’s work bridges resource recovery, pollution control, and circular economy principles, with strong relevance to sustainable development and critical raw material security.
Professor Kazuyuki Kuroda's research lab specializes in the design, synthesis, and functionalization of advanced silica-based hybrid materials, with a focus on layered silicates, mesoporous silica, and nanoscale architectures. The lab pioneers innovative strategies for the controlled self-assembly of siloxane-based precursors to create ordered meso- and microporous structures, as well as large-area exfoliated nanosheets with tailored surface chemistry. Key research directions include surface modification of layered silicates via covalent silylation, development of colloidal and thin-film mesostructured silica with tunable porosity, and the use of external fields (e.g., magnetic fields) to control mesostructure orientation. The lab also explores applications in catalysis, separation, and functional nanomaterials through precise structural control at the nanoscale.
Professor Atsushi Nakajima's research lab specializes in the synthesis, structural characterization, and electronic property analysis of atomic-scale clusters, particularly focusing on organometallic, bimetallic, and metallocluster systems. The lab employs advanced spectroscopic techniques such as photoelectron spectroscopy, laser-induced fluorescence, and time-of-flight mass spectrometry to investigate size- and composition-dependent electronic structures, geometric configurations, and bonding motifs in clusters. Key research directions include the formation of unique network structures in transition metal–organic clusters, the electronic stability of group 3–5 metal–germanium/tin clusters, and the role of ligand and solvent molecules in tuning cluster properties through hydrogen bonding and coordination. The lab's work bridges molecular and materials science, aiming to design functional nanomaterials with tailored electronic and magnetic properties.
