东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Hironori Hojo's research lab focuses on the molecular and cellular mechanisms underlying skeletal development and bone regeneration, with a particular emphasis on osteoblast and chondrocyte differentiation from multipotent progenitors. The lab integrates stem cell biology, single-cell genomics, and in vivo models to dissect gene regulatory networks and signaling pathways—such as hedgehog and Ccl9—that govern skeletal lineage commitment. By combining human pluripotent stem cell-derived models with in vivo transplantation systems, the lab aims to model human endochondral ossification and identify novel therapeutic targets for bone repair.
Professor Junya Kanda's research lab specializes in hematopoietic stem cell transplantation, with a focus on immune reconstitution, graft-versus-host disease (GVHD), and the immunological and iron metabolic factors influencing outcomes in patients with hematologic malignancies. The lab investigates the impact of donor-recipient factors such as HLA matching, ABO compatibility, and graft source on transplant survival and immune recovery. Their work integrates clinical outcomes with molecular and immunological biomarkers, including hepcidin and cytokines, to optimize post-transplant management and improve long-term survival.
Professor Hiroaki Adachi's research lab focuses on plant innate immunity, particularly the molecular mechanisms underlying NLR (nucleotide-binding domain and leucine-rich repeat) immune receptor networks in solanaceous plants. The lab investigates how NLRs recognize pathogen effectors, trigger immune responses such as reactive oxygen species bursts and hypersensitive cell death, and evolve under pathogen pressure. Key research directions include dissecting the functional motifs of helper NLRs like NRC4 and NRCX, identifying effector targets, and exploring the evolutionary dynamics of immune receptor genes such as ZAR1 across flowering plants.
Professor Ayako Kohno's research lab focuses on public health and social welfare issues affecting vulnerable populations, particularly in the context of Malaysia and Japan. The lab investigates the socio-cultural, psychological, and systemic drivers of child marriage, with an emphasis on developing culturally sensitive interventions and awareness programs. It also explores healthcare access and utilization among elderly Japanese migrants, addressing language, trust, and cultural barriers in healthcare systems. The lab integrates qualitative and mixed-methods approaches to inform policy and practice in global health and social development.
Professor Tatsuo Hata's research lab specializes in pancreatic cancer and pancreatic cystic neoplasms, focusing on molecular mechanisms, biomarker discovery, and translational applications. The lab investigates oncogenes such as AURKA and tumor suppressor-related DNA methylation markers in cyst fluid to improve diagnosis and risk stratification. Key research directions include liquid biopsy applications using circulating cell-free DNA, methylation-specific detection of neoplastic potential, and understanding post-surgical complications like hepatic steatosis. The lab integrates molecular pathology with clinical outcomes to advance precision medicine in pancreatic diseases.
Professor Junko Okuyama's research lab focuses on adolescent mental health, particularly in the context of disasters and major life stressors such as pandemics and natural catastrophes. The lab investigates psychological impacts, resilience, and the effectiveness of school-based mental health support systems, drawing on longitudinal studies and real-world disaster responses. A key focus is on developing and validating practical, accessible interventions—such as those led by teachers and school nurses—for adolescents affected by trauma. The lab also contributes to international disaster mental health care by adapting evidence-based practices from Japan’s experiences to global contexts.
Professor Yuichi Kawamoto's research lab specializes in advanced wireless communication systems, with a focus on Internet of Things (IoT) applications, multi-layered satellite networks (MLSNs), and unmanned aerial vehicle (UAV) networks. The lab investigates intelligent data collection, resource allocation, and congestion control to enhance network performance in smart cities, remote areas, and dynamic environments. Key research directions include real-time crowd dynamics management, high-throughput satellite communications, and efficient spectrum utilization in heterogeneous networks.
Professor Xun Tang's research lab specializes in advanced optoelectronic materials, with a primary focus on organic light-emitting diodes (OLEDs) and next-generation battery technologies. The lab pioneers innovative molecular designs and nanostructured materials to achieve high-efficiency, stable, and color-pure white OLEDs through strategies such as energy transfer engineering, host-dopant modulation, and exciplex formation. In parallel, the lab explores self-healing anode materials for lithium-ion batteries, leveraging low-melting-point metals like gallium in carbon-encapsulated nanostructures to enhance cyclability and structural integrity. The overarching research direction emphasizes the rational design of functional materials at the molecular and nanoscale to address critical challenges in energy storage and display technologies.
Professor Hisaya Kojima's research lab specializes in microbial ecology and physiology, with a focus on isolating and characterizing novel autotrophic and sulfur-oxidizing bacteria from freshwater environments. The lab investigates the physiological and genomic properties of these microbes, particularly their roles in sulfur and energy metabolism under varying redox and environmental conditions. A key research direction involves linking genomic information with physiological functions through pure culture studies, especially in chemolithoautotrophic and facultatively anaerobic bacteria. The lab also contributes to understanding microbial community dynamics in stratified lakes, using both cultivation and molecular approaches.
Professor Yasuko Orba's research lab focuses on viral pathogenesis, particularly investigating polyomaviruses and orthopoxviruses in natural animal reservoirs. The lab explores viral replication mechanisms, host-virus interactions, and the cellular responses triggered by viral oncoproteins such as large T antigen. A key research direction involves understanding how viral infections manipulate the host cell cycle and DNA damage response pathways, with implications for viral persistence and oncogenesis. The lab also develops novel antiviral strategies, including RNA interference, to target viral gene expression in infected cells.
Professor Yoko Ogawa's research lab specializes in the immunopathology and clinical management of dry eye disease, particularly in the context of chronic graft-versus-host disease (cGVHD) following allogeneic hematopoietic stem cell transplantation (HSCT). The lab focuses on understanding the role of immune cells—especially T cells—and stromal fibroblasts in the destruction and fibrosis of lacrimal glands, aiming to identify novel therapeutic targets. Key research directions include developing diagnostic metrics for ocular cGVHD, elucidating the mechanisms of fibrotic remodeling in lacrimal tissue, and evaluating immunomodulatory treatments such as FK506 and corticosteroids.
Professor Kazunori Miyamoto's research lab specializes in the development of novel hypervalent iodine(III)- and iodine(V)-based reagents for selective and efficient organic transformations. The lab focuses on metal-free oxidative cleavage of C–C multiple bonds, catalytic Hofmann rearrangements, and the generation of reactive intermediates such as diatomic carbon (C₂) under mild conditions. A central theme is the design of innovative organocatalytic and hypervalent iodine-catalyzed reactions that replace traditional toxic or harsh oxidants with safer, more sustainable alternatives.
Professor Stephan Thürmer's research lab specializes in the experimental investigation of electronic structure and ultrafast dynamics in aqueous environments, with a focus on liquid water, aqueous ions, and hydrogen peroxide. Using advanced techniques such as liquid-jet photoelectron spectroscopy (LJ-PES) and autoionization electron spectroscopy, the lab probes valence electronic states, ionization energies, and relaxation processes in solution with high energy resolution. Key research directions include solvation effects on electronic structure, electron inelastic scattering and probing depth in liquids, and the role of electron correlation and charge delocalization in transient ionic states. The lab combines high-resolution spectroscopy with ab initio quantum chemical calculations to provide atomic-level insights into fundamental processes in condensed-phase water and aqueous solutions.
Professor Akihiro Morita's research lab specializes in theoretical and computational physical chemistry, focusing on interfacial phenomena at the molecular level. The lab develops advanced simulation methods—particularly molecular dynamics and ab initio calculations—to investigate nonlinear optical spectroscopy, such as vibrational sum frequency generation (SFG), at liquid and solid interfaces. Key research directions include the microscopic origin of surface nonlinear optical responses, solute-solvent interactions in complex environments (including supercritical fluids and aqueous electrolytes), and the role of electronic polarization and charge redistribution in interfacial dynamics. The lab emphasizes first-principles approaches to eliminate empirical fitting, enabling direct comparison between simulations and experiments.
Professor Takuya Ishimoto's research lab specializes in advanced materials development for biomedical applications, with a focus on additive manufacturing of metallic biomaterials. The lab pioneers texture-controlled metallic alloys—particularly titanium-based and high-entropy alloys—using selective laser melting to achieve tailored mechanical properties such as low Young’s modulus and enhanced biocompatibility. Key research directions include crystallographic texture engineering, suppression of elemental segregation in multi-component alloys, and the integration of bioactive molecules for bone regeneration. The lab also investigates the relationship between tissue-level microstructure, mineral orientation, and mechanical function in bone to advance implant design and regenerative medicine.
Professor Tomoki Ozawa's research lab specializes in topological photonics and quantum matter, focusing on the interplay between topology, geometry, and quantum phenomena in engineered photonic and ultracold atomic systems. The lab explores synthetic dimensions, topological insulators, and gauge fields in photonic lattices to realize robust quantum transport and simulate exotic many-body phenomena. A central theme is the experimental measurement and theoretical understanding of geometric quantities like the quantum metric and Berry curvature in both photonic and condensed matter systems. The lab also investigates topological effects in driven-dissipative systems and ultracold quantum gases, aiming to bridge fundamental quantum geometry with practical photonic devices and quantum simulation platforms.
Professor Takuya Noguchi's research lab focuses on cellular signaling mechanisms underlying stress responses, apoptosis, and metabolic regulation. The lab investigates key signaling molecules such as ASK1, TAK1, and MAP kinases in the context of oxidative stress, inflammation, and cell death pathways. A central theme is the regulation of kinase activation through protein-protein interactions, post-translational modifications, and redox-sensitive switches. The lab also explores metabolic enzyme regulation, particularly pyruvate kinase isozymes, in metabolic diseases and insulin signaling.
Professor Yukio Tanaka's research lab specializes in topological quantum materials and low-dimensional superconductivity, with a focus on engineering and detecting Majorana fermions in hybrid heterostructures. The lab investigates chiral and time-reversal invariant Majorana bound states in systems such as topological insulators, noncentrosymmetric superconductors, and Josephson junctions involving ferromagnetic insulators. Their work combines theoretical analysis with advanced experimental techniques like angle-resolved photoemission spectroscopy (ARPES) to probe exotic surface states and nonreciprocal responses in quantum materials. A central theme is the interplay between spin-orbit coupling, superconductivity, and broken symmetries to realize topologically protected quasiparticles with potential applications in fault-tolerant quantum computing.
Professor Tetsuo Kondo's research lab specializes in the fundamental understanding and manipulation of cellulose-based materials, focusing on hydrogen bonding, supramolecular structure, and nanoscale morphology. The lab investigates the role of intramolecular and intermolecular hydrogen bonding in determining the physical properties of cellulose and its derivatives, including solubility, crystallinity, and reactivity. A key research direction involves the development of novel cellulose nanostructures—such as nematic-ordered cellulose and cellulose nanofibrils—through controlled biosynthesis and chemical modification, enabling advanced applications in sustainable materials and Pickering emulsions. The lab also explores template-directed biosynthesis and surface engineering to achieve precise control over cellulose nanostructure and functionality.
Professor Satoru Kase's research lab specializes in vitreoretinal diseases, with a focus on the molecular mechanisms underlying retinal and choroidal neovascularization, diabetic retinopathy, and macular hole pathogenesis. The lab investigates key proteins such as alphaB-crystallin and osteopontin in disease progression, utilizing animal models, clinical cytology, and histopathological analysis to explore therapeutic targets. Their work also emphasizes innovative surgical techniques, such as the inverted internal limiting membrane flap, and diagnostic methods using cell block preparations for vitreous samples.
