东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Hisayoshi Matsushima's research lab specializes in electrochemistry and surface science, with a focus on understanding and manipulating electrode surface structures at the atomic level during electrochemical processes. The lab investigates surface reconstructions, electrodeposition mechanisms, and the influence of external fields—particularly magnetic fields—on mass transport and crystal growth in electrochemical systems. Their work spans fundamental studies of metal deposition (e.g., Cu, Bi, Al) on single-crystal electrodes to applied research in energy conversion technologies such as fuel cells and batteries.
Professor Shinsuke Yuasa's research lab specializes in regenerative medicine and stem cell biology, with a focus on induced pluripotent stem cells (iPSCs) and their applications in disease modeling, drug screening, and personalized medicine. The lab investigates cardiac and skeletal muscle development, emphasizing the role of key transcriptional regulators like Zac1 in cardiogenesis and congenital heart disease. Using advanced technologies such as deep learning and single-cell analysis, the lab develops innovative, staining-free methods to identify and characterize stem cell-derived cell types, including endothelial cells. The lab also explores epigenetic mechanisms—particularly oocyte-specific factors like H1foo—that enhance iPSC reprogramming and improve the quality and functionality of pluripotent stem cells.
Professor Katsunori Mizuno's research lab specializes in ultrasonic wave propagation in biological tissues, particularly cancellous bone, with a focus on understanding the anisotropic and microstructural influences on fast and slow wave phenomena. The lab combines experimental ultrasonic measurements using custom transducers with advanced imaging techniques such as X-ray micro-computed tomography to quantify structural anisotropy and bone microarchitecture. Their work contributes to the development of non-invasive ultrasound-based diagnostics for bone quality assessment, with potential applications in clinical evaluation of osteoporosis and fracture risk. Additionally, the lab has explored protein tyrosine phosphatases in cellular signaling, particularly in immune regulation and disease mechanisms.
Professor Tatsuhiro Hisatsune's research lab focuses on aging-related cognitive decline and neurodegenerative diseases, with a central emphasis on identifying and validating nutritional and microbial interventions to preserve brain health in older adults. The lab investigates the neuroprotective roles of bioactive compounds such as anserine/carnosine, probiotics like *Lactiplantibacillus plantarum* OLL2712, and functional foods such as matcha green tea, particularly in individuals at risk for Alzheimer’s disease, including those carrying the APOE ε4 allele. Their work integrates clinical trials, neuroimaging, and molecular mechanisms to explore the microbiome-gut-brain axis, cholinergic modulation, and vascular-cognitive interactions. The lab aims to translate basic neuroscience into practical, evidence-based nutritional strategies for healthy brain aging.
Professor Alexander Kusenko's research lab focuses on theoretical particle physics and cosmology, with a strong emphasis on dark matter candidates such as sterile neutrinos and Q-balls, as well as the astrophysical signatures of new physics. The lab investigates the interplay between particle physics beyond the Standard Model and cosmological observations, including pulsar velocities, intergalactic magnetic fields, and gamma-ray halos. Key research directions include the stability of the electroweak vacuum, the detection of dark matter via X-ray and gamma-ray telescopes, and the phenomenology of nontopological solitons. The group also explores connections between neutrino physics, supernova dynamics, and large-scale structure formation.
Professor Yuichi Shimakawa's research lab specializes in the crystal chemistry and physical properties of complex oxide materials, with a focus on ferroelectric, multiferroic, and superconducting oxides. The lab investigates structure-property relationships in bismuth-layered perovskites, A-site-ordered perovskites, and thallium-based cuprates, using advanced techniques such as neutron powder diffraction and electronic structure calculations. Key research directions include understanding the role of cation non-stoichiometry, ion substitution, and local structural distortions in tuning ferroelectric polarization and transition temperatures. The lab also explores the influence of orbital hybridization and Jahn-Teller effects on electronic and magnetic behavior in complex oxides.
Professor Tatsushi Igaki's research lab focuses on the molecular mechanisms underlying cell competition, apoptosis, and tumor suppression in Drosophila, with a particular emphasis on how cellular fitness, endoplasmic reticulum stress, and intercellular communication govern tissue homeostasis and tumor suppression. The lab investigates key regulators such as Xrp1, DIAP1, and Drob-1, exploring their roles in cell death, proteostasis, and non-autonomous signaling in epithelial tissues. By integrating genetic screens, cell biological analyses, and molecular dissection, the lab uncovers conserved pathways that prevent tumorigenesis through fitness-based cell elimination and microenvironmental crosstalk. Their work reveals how stress responses and apoptotic pathways are co-opted to maintain tissue integrity and suppress malignant progression.
Professor Hideki Makishima's research lab specializes in the molecular genetics and pathogenesis of myeloid neoplasms, with a focus on identifying somatic mutations and chromosomal abnormalities underlying diseases such as myelodysplastic syndromes (MDS), chronic myeloid leukemia (CML), and myeloproliferative neoplasms (MPN). The lab employs advanced genomic technologies, including whole-exome sequencing and single-nucleotide polymorphism (SNP) arrays, to uncover mutations in spliceosomal genes (e.g., SF3B1, U2AF1), tyrosine kinase regulators (e.g., CBL, CBLB), and epigenetic modifiers (e.g., TET2, ASXL1, IDH1/2) that drive disease progression. A key research direction involves understanding the functional impact of copy-neutral loss of heterozygosity (uniparental disomy) and its role in clonal evolution and leukemogenesis. The lab integrates genomic profiling with clinical phenotypes to elucidate disease mechanisms and improve diagnostic and prognostic stratification.
Professor Randy Jalem's research lab specializes in computational materials science with a focus on designing advanced solid electrolytes for all-solid-state batteries. The lab employs first-principles calculations, molecular dynamics, and machine learning-driven approaches to predict and optimize ionic conductivity, structural stability, and ion migration mechanisms in oxide and chalcogenide materials. Key research directions include the development of garnet- and olivine-type solid electrolytes, doping strategies to enhance ionic transport, and the integration of Bayesian optimization and multivariate analysis to accelerate materials discovery. The lab's work bridges theoretical modeling with practical battery applications, targeting high energy density, safety, and long-term stability in next-generation energy storage systems.
Professor Abhishek Sharma's research lab specializes in advanced materials processing, with a primary focus on friction stir-based techniques for developing high-performance aluminum matrix composites. The lab explores innovative methods such as friction stir processing (FSP), friction stir alloying, and solid-state friction surfacing to enhance mechanical, wear, and corrosion properties of lightweight alloys by incorporating reinforcements like SiC, graphite, and graphene nanoplatelets. A key emphasis is placed on microstructure-property correlations, defect suppression, and the in-situ generation of few-layer graphene during processing. The lab also investigates functional nanocomposites, including polymer-clay systems for ion-conducting applications, demonstrating a broad yet focused approach in materials synthesis and characterization.
Professor Satoshi Muratsugu's research lab specializes in the design and synthesis of functional molecular materials with tailored electronic and redox properties, focusing on photoresponsive systems, molecularly imprinted catalysts, and multimetallic complexes. Key research directions include the development of reversible photochromic switches based on dimethyldihydropyrene-ferrocene architectures, the creation of shape-selective heterogeneous catalysts through molecular imprinting on silica supports, and the exploration of redox-active multinuclear complexes for applications in catalysis and electron transfer processes. The lab integrates advanced spectroscopic techniques, X-ray diffraction, and computational methods to understand structure–property relationships at the molecular level.
Professor Yuzo Yamasaki's research lab specializes in cardiovascular imaging and interventional radiology, with a focus on chronic thromboembolic pulmonary hypertension (CTEPH). The lab investigates advanced imaging techniques such as dual-layer spectral CT, dynamic chest radiography, and Holter monitoring to assess right ventricular and right atrial function, pulmonary vascular resistance, and fibrosis. Key research directions include evaluating the diagnostic performance of non-invasive imaging modalities, understanding the hemodynamic and functional impacts of interventions like balloon pulmonary angioplasty (BPA), and exploring biomarkers such as BNP in relation to cardiac function. The lab also contributes to oncology imaging by studying rare metastatic patterns in renal cell carcinoma, emphasizing the importance of surgical resection for solitary metastases.
Professor Guo-Wei Lu's research lab specializes in advanced optical communication technologies, with a focus on high-speed, high-spectral-efficiency optical transmission systems. The lab explores all-optical signal processing techniques such as wavelength conversion, format conversion, and phase manipulation using nonlinear fiber and semiconductor devices. Key research directions include the development of robust photonic components for extreme environments, ultra-high-speed modulation formats (e.g., 16-QAM, DQPSK, and 320-Gb/s RZ-DQPSK), and energy-efficient optical networking solutions for future datacenters. The lab also investigates novel schemes for optical multicast and signal regeneration to enhance network scalability and performance.
Professor Osamu Seto's research lab specializes in theoretical particle physics and cosmology, focusing on fundamental physics beyond the Standard Model and its implications for the early universe. Key research directions include resolving the Hubble tension through early dark energy and extra radiation models, exploring anomalies in nuclear decays via radiative seesaw mechanisms with gauged B−L symmetry, and investigating supersymmetric and axion-like particles as candidates for warm or cold dark matter. The lab also studies inflationary dynamics, particularly the role of higher-order corrections in supergravity models and their impact on cosmic structure formation.
Professor Kazuyuki Ishii's research lab specializes in the photophysical and photochemical properties of metalloporphyrin and phthalocyanine complexes, with a focus on excited-state dynamics, electron paramagnetic resonance (EPR) spectroscopy, and energy/electron transfer processes. The lab employs advanced time-resolved techniques such as time-resolved EPR (TREPR) and transient absorption to investigate spin states, intersystem crossing, and triplet state behavior in functionalized macrocyclic semiconductors. A key research direction involves the development of porphyrin- and phthalocyanine-based probes for biological applications, including ascorbic acid detection and photodynamic therapy (PDT) agents. The lab also explores two-photon processes and selective photoreactions for potential use in biomedical imaging and theranostics.
Professor Koji Harano's research lab specializes in advanced materials chemistry and nanoscale science, focusing on the atomic-level understanding of molecular self-assembly, crystal nucleation, and dynamic reaction mechanisms. The lab employs cutting-edge electron microscopy techniques—particularly single-molecule and time-resolved electron microscopy—to visualize and analyze the structural evolution of organic and metal–organic nanostructures, carbon nanomaterials, and reaction intermediates in real time. Key research directions include the design of stimuli-responsive supramolecular architectures, the formation mechanisms of carbon fibers and carbon nanotubes, and the dynamics of cascade reactions in carbon-rich systems. Their work bridges molecular design with functional materials, enabling precise control over nanostructure and properties at the atomic scale.
Professor Yohei Fuji's research lab specializes in strongly correlated quantum systems, with a focus on topological quantum phases, entanglement dynamics, and quantum criticality in low-dimensional systems. The lab explores symmetry-protected topological order, fracton phases, and fractional quantum Hall states using advanced theoretical frameworks such as conformal field theory, coupled-wire constructions, and quantum trajectory methods. Key research directions include the interplay between topology, entanglement, and measurement-induced phase transitions, as well as the microscopic realization of exotic quantum orders in spin chains and 2D lattice models.
Professor Kohei Nishitani's research lab focuses on the pathogenesis of Staphylococcus aureus infections, particularly in the context of orthopedic implant-associated osteomyelitis and surgical site infections. The lab investigates host-pathogen interactions, biofilm formation, immune evasion mechanisms, and the role of host mediators such as prostaglandin E2 in joint homeostasis and inflammation. A key emphasis is on developing clinically relevant animal models and translational diagnostics to guide personalized therapies and vaccine development.
Professor Takashi Hirama's research lab focuses on membrane biophysics and cellular lipid dynamics, particularly the roles of anionic phospholipids such as phosphatidylserine and phosphoinositides in shaping membrane curvature and organizing specialized membrane domains like caveolae. The lab investigates how cholesterol modulates electrostatic forces and lipid-protein interactions to regulate membrane remodeling, endocytosis, and cellular signaling. Their work also extends to clinical translational research in liver transplantation and critical care, exploring outcomes, timing of listing, and supportive therapies such as CRRT. Additionally, they apply innovative microbiological concepts—like the 'battlefield hypothesis'—to differentiate pathogenic from colonizing commensal organisms in pneumonia.
Professor Hidemichi Fujii's research lab specializes in environmental and productivity analysis, focusing on the integration of economic performance with environmental sustainability across various sectors. The lab employs advanced data envelopment analysis (DEA) models—particularly the weighted Russell directional distance model—to evaluate efficiency and productivity in industries, banking, wastewater management, and forest ecosystem services. Research directions emphasize pollution abatement, regional disparities in environmental performance, and the drivers of technological innovation in biotechnology and industrial emissions. The lab also conducts decomposition analysis to identify key factors behind changes in environmental and economic outcomes.
