探索全球顶尖大学的研究室——研究领域与主要论文一览无余。
Professor Yong Shin's research lab specializes in the development of innovative microfluidic and nanomaterial-based platforms for point-of-care molecular diagnostics and liquid biopsy applications. The lab focuses on advancing sensitive, rapid, and label-free detection of genetic and epigenetic biomarkers—such as single-point mutations, cell-free nucleic acids, and extracellular vesicles—using cutting-edge technologies like silicon microring sensors, SERS substrates, and magnetic nanoparticle composites. A central theme in the lab’s work is the design of non-chaotropic, high-efficiency nucleic acid capture systems and isothermal amplification techniques to improve clinical translation of molecular diagnostics.
Professor Bong-Kyu Choi's research lab focuses on the molecular mechanisms of bacterial pathogenesis and host-microbe interactions, particularly in periodontal and neurodegenerative diseases. The lab investigates the role of bacterial virulence factors, such as extracellular vesicles and quorum-sensing molecules like AI-2, in disease progression and systemic inflammation. Key research directions include the pathogenesis of periodontitis, the contribution of spirochetes and other oral pathogens to chronic inflammation, and the neurotoxic mechanisms of alpha-synuclein in Parkinson’s disease and dementia with Lewy bodies. The lab employs molecular microbiology, 16S rRNA gene sequencing, and advanced imaging techniques to explore microbial diversity and host-pathogen crosstalk.
Professor Jeong Mo Bae's research lab specializes in molecular oncology, with a primary focus on the molecular pathogenesis and prognostic biomarkers of colorectal and gastric cancers. The lab investigates molecular subtypes, epigenetic alterations such as DNA methylation (including ALU and LINE-1 hypomethylation), and the role of key transcription factors like CDX2 and CK20 in tumor progression. A central theme is the integration of molecular profiling—especially microsatellite instability (MSI) and CpG island methylator phenotype (CIMP)—to improve risk stratification, understand carcinogenesis pathways, and guide personalized treatment strategies.
Professor Won-Kyung Ho's research lab specializes in cellular and molecular mechanisms underlying ion channel regulation, with a primary focus on potassium channels in cardiac and neuronal tissues. The lab investigates how cellular signaling pathways, including AMP-activated protein kinase (AMPK) and phosphoinositide metabolism, modulate ion channel trafficking and function in response to metabolic and physiological cues. Key research directions include the regulation of HERG and other voltage-gated K+ channels by intracellular second messengers, pharmacological agents, and ion concentrations, with implications for arrhythmia and drug-induced cardiotoxicity. The lab also explores lipid-protein interactions, particularly the role of phosphoinositides in subcellular targeting and functional regulation of ion channels and transporters.
Professor Yeon Ho Je's research lab specializes in virology and molecular entomology, focusing on baculovirus-based protein expression systems and the development of novel insect growth regulators. The lab investigates host-virus interactions, particularly how baculoviruses like AcMNPV manipulate host gene expression to enhance protein production or serve as bioinsecticides. A key focus is on engineering baculoviruses to co-localize foreign proteins within occlusion bodies for improved yield and stability, while also exploring natural compounds from entomopathogenic fungi as sustainable alternatives to chemical insecticides. The lab integrates omics technologies such as RNA-seq to decode regulatory networks in insect hosts during viral infection.
Professor Sangyoub Lee's research lab specializes in theoretical and computational physical chemistry, focusing on reaction dynamics in solution, particularly diffusion-influenced bimolecular reactions and electron/charge transfer processes. The lab develops advanced theoretical frameworks—such as the solution reaction path Hamiltonian (SRPH) and variational transition state theory—incorporating anharmonicity, solvation effects, and reaction path curvature to predict rate constants with high accuracy. Their work bridges fundamental chemical kinetics with practical applications in drug discovery and process safety, demonstrating strong interdisciplinary impact in computational chemistry and chemical engineering. The lab also contributes to virtual screening methodologies and risk assessment tools, integrating theoretical models with real-world data.
Professor Kyoungsoo Park's research lab specializes in computational mechanics and fracture mechanics, with a focus on advanced numerical methods for modeling complex material behaviors. The lab develops innovative finite element and virtual element methods to simulate dynamic cohesive fracture, including adaptive mesh refinement and enrichment techniques for accurate crack propagation. Key research directions include cohesive zone modeling, fatigue crack growth, and multi-scale microstructure reconstruction using multi-modal imaging. The lab also pioneers integration schemes for handling weak singularities and stability in extended finite element methods.
Professor Eun Mi Hwang's research lab focuses on ion channel biology, particularly the molecular mechanisms underlying cellular ion homeostasis and their roles in disease. The lab investigates the regulation of ion channel trafficking and function, with a strong emphasis on TRPM4 and volume-regulated anion channels (VRACs), linking these channels to neuronal cell death and cancer progression. Using molecular, cellular, and pharmacological approaches, the lab explores how ion channel dysfunction contributes to pathological conditions and identifies novel therapeutic targets. Their work also delves into epigenetic regulation of ion channel expression, as seen in the role of histone deacetylase inhibitors in restoring channel function in drug-resistant cancer cells.
Professor Kwangmo Yang's research lab focuses on cancer immunotherapy and tumor immunology, with a particular emphasis on dendritic cell-based vaccines, cancer stem-like cells (CSCs), and epigenetic regulation in tumorigenesis. The lab investigates novel immunomodulatory strategies—such as anti-CTLA-4 therapy and DC vaccination using CSC-specific antigens like CD44 and EpCAM—to enhance anti-tumor immunity. It also explores the role of chromatin regulators, such as macroH2A1, in maintaining cancer stem cell properties and treatment resistance in bladder cancer. The overarching goal is to develop innovative, targeted immunotherapies that overcome immune evasion and improve outcomes in solid tumors.
Professor Jaeseon Lee's research lab specializes in advanced thermal management for high-power-density electronics, with a primary focus on innovative cooling technologies to address extreme heat dissipation challenges in defense and high-performance computing applications. The lab investigates microchannel heat sinks integrated with refrigeration cycles—particularly R134a-based systems—enabling precise temperature control below 55°C even at heat fluxes exceeding 100 W/cm². Research also emphasizes the mitigation of system inefficiencies such as wet compression and liquid entrainment, aiming to enhance reliability and performance of direct and indirect refrigeration cooling systems. The lab’s work bridges fundamental heat transfer principles with practical engineering solutions for next-generation electronic systems.
Professor Hyunyong Choi's research lab specializes in the fundamental physics and optoelectronic properties of two-dimensional materials and topological quantum materials. The lab focuses on light-matter interactions, particularly in van der Waals heterostructures and 3D topological insulators, exploring ultrafast carrier dynamics, spin transport, and nonlinear terahertz responses. Using advanced spectroscopic techniques such as time-resolved terahertz spectroscopy and helicity-dependent photocurrent measurements, the group investigates quantum phenomena like interlayer excitons, spin Hall effects, and nonlinear optical generation at the atomic scale. Their work bridges nanoscale material design with next-generation optoelectronic and spintronic devices.
Professor Jin-Bae Kim's research lab focuses on vascular biology, regenerative medicine, and nanotoxicology, with a strong emphasis on translational applications. The lab investigates endothelial dysfunction and vascular repair mechanisms using noninvasive methods like RH-PAT, explores the therapeutic potential of human tissue-derived mesenchymal stem cells (hTMSCs) in regenerative therapies, and examines the biological and environmental impacts of nanomaterials—particularly silver nanoparticles—in consumer products. The lab also studies diabetic vascular complications and drug-induced liver injury, aiming to understand underlying mechanisms and improve clinical outcomes.
Professor Min-Hye Kim's research lab focuses on the role of microbial components, particularly bacterial extracellular vesicles (EVs), in the pathogenesis of allergic and immune-mediated diseases such as atopic dermatitis and asthma. The lab investigates systemic microbial signatures and host-microbe interactions using integrative approaches combining metagenomics, proteomics, and clinical biomarker analysis. A key research direction involves translating microbial EV profiles into diagnostic and therapeutic strategies for severe and refractory type 2 inflammatory diseases.
Professor Jae Eun Oh's research lab specializes in cementitious materials and sustainable construction materials, with a focus on the hydration mechanisms, chloride binding behavior, and pore structure evolution in alkali-activated materials and ground granulated blast-furnace slag (GGBFS). The lab investigates the role of key phases such as monosulfoaluminate and C-A-S-H gels in anion exchange and immobilization, particularly under aggressive environments like seawater exposure. Using advanced characterization techniques like STXM, XANES, and XRD, the lab explores the long-term durability and performance of alternative cements, aiming to develop eco-friendly and durable construction materials.
Professor Hyejin Jung's research lab focuses on cardiovascular health, particularly the pathophysiological mechanisms of atherosclerosis and hypertension, with an emphasis on cellular signaling, oxidative stress, and endothelial dysfunction. The lab investigates protective agents such as chlorogenic acid and non-pharmacological interventions like acupuncture in improving cardiovascular outcomes. It also explores broader health-related quality of life and long-term management strategies in hypertensive and post-stroke populations.
Professor Juyeon Park's research lab focuses on human-centered design and health technology, with a strong emphasis on body image, inclusivity in apparel and footwear, and the psychological impacts of virtual self-representation. The lab investigates wearable technologies, personal protective equipment, and virtual avatars to improve user experience, mobility, and well-being across diverse populations. Research spans from anthropometric data collection and 3D body scanning to psychological outcomes such as self-esteem and body perception, particularly in relation to size inclusivity and health behavior. The lab also explores metrological standards in battery technology, reflecting a multidisciplinary approach bridging engineering, design, and psychology.
Professor Sungho Kang's research lab focuses on intelligent connected vehicle systems, with an emphasis on integrating Internet of Things (IoT) technologies, cloud computing, and voice-based virtual assistants to enhance automotive user experiences. The lab explores advanced simulation techniques for efficient design verification in complex automotive systems, leveraging error modeling to evaluate the effectiveness of validation patterns. Research also spans human-machine interaction, particularly through voice-activated personal assistants that bridge home and vehicle environments. The lab's work aims to develop smarter, safer, and more intuitive vehicular software and services.
Professor Young Woo Eom's research lab specializes in mesenchymal stem cell (MSC) biology and regenerative medicine, with a primary focus on liver fibrosis and cirrhosis. The lab investigates the therapeutic potential of MSCs and adipose-derived stem cells (ASCs) in promoting liver regeneration, modulating immune responses, and reducing fibrosis through paracrine signaling and differentiation. Key research directions include optimizing stem cell isolation and culture techniques—particularly for cryopreserved ASCs—and enhancing MSC proliferation and differentiation using growth factors and antioxidants like l-ascorbic acid 2-phosphate. The lab also explores the dual role of MSCs in tumor microenvironments, balancing their regenerative benefits with potential risks in oncological contexts.
Professor Yongseok Choi's research lab specializes in medicinal chemistry and drug discovery, with a focus on repurposing existing drugs and developing novel small-molecule therapeutics for inflammatory and autoimmune diseases. The lab investigates epigenetic modulators, such as histone deacetylase (HDAC) inhibitors, and targets key proinflammatory cytokines like interleukin-6 (IL-6) to address unmet medical needs. A major emphasis is placed on designing and synthesizing conformationally locked nucleosides and bioactive compounds with improved pharmacological profiles, including oral bioavailability and reduced toxicity.
Professor Mingyu Kim's research lab specializes in number theory, with a focus on the representation of integers by quadratic forms and generalized polygonal numbers. The lab investigates regular and odd-regular quadratic forms, particularly in ternary and higher ranks, aiming to classify forms that represent all locally represented integers. A central theme is determining when certain linear combinations of polygonal numbers exhaust all sufficiently large integers, resolving long-standing conjectures and establishing finiteness and boundedness results. The work combines analytic number theory, modular forms, and arithmetic geometry to address classical problems in additive number theory.
