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A-Rung Lee

Seoul National University · Social Sciences

About the Lab

Professor A-Rung Lee's research lab focuses on molecular and translational biomedical research, with a strong emphasis on epigenetic regulation in reproductive tissues, tumor suppressor mechanisms in gestational trophoblastic diseases, and novel therapeutic strategies for autoimmune and inflammatory disorders such as rheumatoid arthritis. The lab also investigates psychological mechanisms related to anxiety and depression through cognitive and behavioral approaches, particularly the role of mental imagery in future thinking. Additionally, the lab explores socio-technical issues, including public trust in government and e-government adoption amid societal stressors like terrorism.

epigeneticstumor suppressorrheumatoid arthritisfuture thinkinge-government

Research Overview

Papers
37
Total Citations
247
Papers (5y)
12
Primary Field
Social Sciences

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2016
2017
2018
2019
2023
Citations per year (5y)
7total
20162017201820192023

Selected Papers

15
1
Article|148 citations·2009
DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen
Youhei Yamagata, Hiromi Asada, Isao Tamura, Lee Lee, Ryo Maekawa, K Taniguchi, Toshiaki Taketani, Aki Matsuoka, H. Tamura, Norihiro Sugino
SJR Q1Human ReproductionOA

BACKGROUND: Epigenetic regulation may be involved in modulation of gene expression during the normal cyclic changes of the human endometrium. We investigated expression of DNA methyltransferases (DNMTs) in endometrium during the menstrual cycle and the influence of sex steroid hormones on DNMT in endometrial stromal cells (ESC) in culture. METHODS: Expression of DNMT1, DNMT3a and DNMT3b was assessed by immunohistochemistry and real-time RT-PCR in endometrial tissue (n = 42 women). ESC (n = 3 wom

ImmunologyImmunology and Microbiology
2
Article|25 citations·2013
Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src signaling pathway activation
Victor Mak, Lee Lee, Michelle K.Y. Siu, Oscar Gee‐Wan Wong, Xin Lü, Hys Ngan, E. S. Y. Wong, Any Cheung
SJR Q1CarcinogenesisOA

Gestational choriocarcinoma is a malignant tumor derived from placental trophoblast and the most aggressive member of gestational trophoblastic disease (GTD). Apoptosis-stimulating protein of p53-2 (ASPP2) is a member of ASPP family that transactivates p53 and thereby functions as a tumor suppressor. In this study, the expression profile of ASPP2 in choriocarcinoma was examined in comparison with normal placentas and hydatidiform moles, the latter being a type of GTD that carries malignant poten

Public Health, Environmental and Occupational HealthMedicine
3
Article|25 citations·2011
Anti-inflammatory and Anti-arthritic Effects of a Novel Leflunomide Analogue, UTL-5b (GBL-5b)
John M. Shaw, Ben Chen, Wen-Hsin Huang, Lee Lee, Dustin Zeng
American Journal of Biomedical SciencesOA

Rheumatoid arthritis (RA) is a common disease characterized by chronic inflammation and irreversible destruction of articular cartilage and bone. In this report, we examined the anti-inflammatory and anti-arthritic effects of a novel leflunomide analogue, UTL-5b (also known as GBL-5b), for potential RA treatment. Using a carrageenan-induced edema study in rats, UTL-5b exhibited a better anti-inflammatory effect as compared with leflunomide and its metabolite. The chronic efficacy of UTL-5b was e

RheumatologyMedicine
4
Article|22 citations·2010
Downregulation of ASPP1 in gestational trophoblastic disease: correlation with hypermethylation, apoptotic activity and clinical outcome
Victor Mak, Lee Lee, Michelle K.Y. Siu, Oscar Gee‐Wan Wong, Xin Lü, Hys Ngan, Esther S.Y. Wong, Any Cheung
SJR Q1Modern PathologyOA
Public Health, Environmental and Occupational HealthMedicine
5
Article|13 citations·2005
Risk of Terrorism, Trust in Government, and e-Government Services: An Exploratory Study of Citizens’ Intention to use e Government Services in a Turbulent Environment
Lee Lee, Hengyi Rao
York University Digital Library (York University)OA

For the last several years, US citizens have been experiencing severe threats of terrorism. While such threats can significantly impact important factors for effective government operations such as citizens’ information demand and attitude toward the government, little is known about their potential effect on citizens’ acceptance of e-Government services. In order to fill this gap, this study examines the effects of perceived risks of terrorism and trustworthiness of the government, on citizens’

Political Science and International RelationsSocial Sciences
6
Article|4 citations·2023
The Effect of IMC Activities of Professional Baseball Teams through ESG Management on Perceived Value and Team Image
Lee Lee, Hyo-Jin Ji, Se-Jin Ko, Jung-Jin Park
Korean Journal of Sports Science

The purpose of the study is to find out the relationship between AD, PS, SP, events, and PR, which are factors of IMC activities of Korean professional baseball teams through ESG management, on consumers&quot perceived value, team image. In addition, we aim to present empirical basic data for revitalizing ESG activities of korean professional baseball teams as new management activities of sports companies. Accordingly, the population of the study was Korean professional baseball fans through ESG

Public Health, Environmental and Occupational HealthMedicine
7
Article|2 citations·2023
삽화적 미래사고 구체성과 불안 및 우울 간의 관계
이아롱, 이훈진

본 연구는 삽화적 미래사고 구체성과 불안 및 우울 간의 관계를 탐색하였다. 범불안과 관련이 높은 심리적 변인들의 영향을 배제한 후에도 삽화적 미래사고 구체성이 범불안 수준과 유의미한 연관성을 보이는지 살펴보았으며, 삽화적 미래사고 구체성과 우울 간의 관계 및 삽화적 미래사고를 구체적으로 떠올리는 데 영향을 미치는 변인들을 확인하였다. 참여자 165명(남 58명, 여 107명, 평균 연령 24.5세)을 대상으로 미래의 부정적인 상황, 부정적인 상황에 대처하는 상황, 긍정적인 상황을 구체적으로 기술하도록 하였고, 개정된 자서전적 면담 체계를 기반으로 각 조건별 삽화적 미래사고 구체성 수준을 평정하였다. 범불안과 우울 수준을 측정하기 위해 범불안장애 7문항 척도(GAD-7) 및 한국판 역학연구센터 우울척도(K-CES-D)를 사용하였다. 위계적 회귀분석 결과, 미래의 부정적인 상황에 대한 삽화적 미래사고 구체성은 우울 및 걱정의 설명량을 통제한 후에도 범불안 수준을 추가적으로 설명하였다.

8
Article|1 citations·1983
DNA metabolism during infection of Anacystis nidulans by cyanophage AS-1: 5 biophysical characterization of PIL-DNA
Lee Lee, Gerald E. Cohn, K. H. Blashka
Microbios
EcologyEnvironmental Science
9
Article|1 citations·1976
The Presidency of the United States of America
Lee Lee
復興崗學報
Political Science and International RelationsSocial Sciences
10
Article|0 citations·2023
The relationship between grit, academic self-efficacy, and college life adjustment in female college students" sports activities
Lee Lee
Korean Journal of Sports Science

This study analyzes the relationship between grit, academic self-efficacy, and college life adaptation of female college students&quot sports activities, and prepares measures to induce increased sports activities and college life adaptation of female college students through this in the future. The purpose is to provide useful data for establishing an effective operation plan for preparation.<br/> In order to secure basic data for the study, female college students who had experience directly p

Information SystemsComputer Science
11
dissertation|0 citations·2008
The ASPP family in gestational trophoblastic disease
Lee Lee
OA
Public Health, Environmental and Occupational HealthMedicine
12
Article|0 citations·1996
A Study on Improving the Efficiency of Magnetic Abrasive Polishing for Die and Mold Surfaces
Lee Lee, Nakagawa Takeo, Masahiro Anzai
Biomedical EngineeringEngineering
13
Article|0 citations·2023
The Effect of Mentoring Experience of Dance Major on Immersion and grit
Lee Lee, Juyeon Kim
Korean Journal of Sports Science

The purpose of this study is to investigate the effect of the mentoring experience of dance majors on immersion and grit. In order to achieve the research purpose, 202 university dance major students were selected as research subjects. Data analysis was conducted using spss 18.0, followed by frequency analysis, exploratory factor analysis, reliability analysis, correlation analysis, and regression analysis to draw the following conclusions.<br/> First, among the sub-factors of mentoring experien

Sociology and Political ScienceSocial Sciences
14
Article|0 citations·2015
‘복잡성’으로서의 일본/일본인 = Japan/Japanese as ‘Complexity’
Lee Lee
Trans-HumanitiesOA

서평 '복잡성'으로서의 일본/일본인 이한정 (상명대학교) 일본의 근대화는 서양과 조우하면서 시작되었다.18세기에 네덜란드 학문이라 일컫는 난학(蘭學)이 서양의 학문으로 일찍이 일본에 유입된 일 은 있었으나, 경제, 사회제도, 문화 등 서양 문명 전반을 일본이 총체적으 로 받아들인 것은 19세기 중반 이후부터다.이 과정에서 서양 문물을 맹목 적으로 받아들이는 일본인의 모습을 서양인들은 '원숭이 흉내'라는 표현 을 사용하여 묘사했다.1883년에 외국인 접대소의 명목으로 도쿄 한복판 에 세워진 서양식 건물 로쿠메이칸(鹿鳴館)에서는 불야성을 이루며 서양 인과 일본인이 어우러진 화려한 연회와 무도회가 개최되었고, 여기에 참 석하는 일본인은 서양식 연미복이나

Cultural StudiesSocial Sciences
15
Article|0 citations·2023
The effect of COVID-19 risk perception on stress and exercise adherence intention for sports participants
Lee Lee, Sang-Back Nam
Korean Journal of Sports Science

The purpose of this study is to investigate the effect of COVID-19 risk perception on stress and exercise adherence intention for sport participants. Preparing for COVID-19 situation and POST-COVID conditions, this study is to provide basic data for establishing an environment for exercise adherence intention for sports participants and establishing marketing strategy.<br/> The method used in the study is questionnaire, it was conducted for Adult men and women over 20 years of age in sports part

Information SystemsComputer Science

Research Areas

Public Health, Environmental and Occupational HealthPolitical Science and International RelationsCultural StudiesInformation SystemsElectrical and Electronic EngineeringSociology and Political Science

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