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Chang-Hoon Koo

Seoul National University · Medicine

About the Lab

Professor Chang-Hoon Koo's research lab specializes in perioperative medicine with a focus on enhancing patient outcomes through innovative anesthetic techniques and technologies. The lab investigates the clinical efficacy of virtual reality in reducing preoperative anxiety, regional anesthesia techniques like the erector spinae plane block for postoperative pain control, and optimal anesthetic strategies such as oxygen concentration management and extubation techniques in pediatric and adult patients. Their work emphasizes evidence-based approaches to minimize complications and improve recovery in surgical populations, particularly in the elderly and pediatric cohorts.

perioperative medicineregional anesthesiavirtual reality in anesthesiapostoperative outcomesanesthetic techniques

Research Overview

Papers
85
Total Citations
1,253
Papers (5y)
27
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
27total
2022
2023
2024
2025
2026
Citations per year (5y)
96total
20222023202420252026

Selected Papers

15
1
Article|91 citations·2020
The Effect of Virtual Reality on Preoperative Anxiety: A Meta-Analysis of Randomized Controlled Trials
Chang‐Hoon Koo, Jin‐Woo Park, Jung‐Hee Ryu, Sung‐Hee Han
SJR Q1Journal of Clinical MedicineOA

Virtual reality (VR), a technology that provides a stimulated sensory experience, has recently been implemented in various fields of medicine. Several studies have investigated the efficacy of VR on preoperative anxiety. The purpose of this meta-analysis was to validate whether VR could relieve preoperative anxiety in patients undergoing surgery. Electronic databases were searched to identify all randomized controlled trials (RCTs) investigating the effect of VR on preoperative anxiety. The prim

Social PsychologyPsychology
2
Review|84 citations·2021
Efficacy of Erector Spinae Plane Block for Analgesia in Thoracic Surgery: A Systematic Review and Meta-Analysis
Chang‐Hoon Koo, Hun‐Taek Lee, Hyo‐Seok Na, Jung‐Hee Ryu, Hyun‐Jung Shin
SJR Q2Journal of Cardiothoracic and Vascular Anesthesia
SurgeryMedicine
3
Article|74 citations·2017
Neutrophil, Lymphocyte, and Platelet Counts and Acute Kidney Injury After Cardiovascular Surgery
Chang‐Hoon Koo, Dhong Eun Jung, Yoon Sang Park, Jungil Bae, Youn Joung Cho, Won Ho Kim, Jae-Hyon Bahk
SJR Q2Journal of Cardiothoracic and Vascular Anesthesia
NephrologyMedicine
4
Article|59 citations·2017
Intraoperative naloxone reduces remifentanil-induced postoperative hyperalgesia but not pain: a randomized controlled trial
Chang‐Hoon Koo, Susie Yoon, Bo Rim Kim, Y.J. Cho, T.K. Kim, Younghoon Jeon, Jeong‐Hwa Seo
SJR Q1British Journal of AnaesthesiaOA
SurgeryMedicine
5
Review|54 citations·2018
Deep vs. Awake Extubation and LMA Removal in Terms of Airway Complications in Pediatric Patients Undergoing Anesthesia: A Systemic Review and Meta-Analysis
Chang‐Hoon Koo, Sun Lee, Seung Young Chung, Jung‐Hee Ryu
SJR Q1Journal of Clinical MedicineOA

The purpose of this study was to compare the incidence of airway complications between extubation under deep anesthesia (deep extubation) and extubation when fully awake (awake extubation) in pediatric patients after general anesthesia. A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) statement standards. The review protocol was registered with the International Prospective Register of Systematic Reviews (registr

Anesthesiology and Pain MedicineMedicine
6
Article|42 citations·2020
The Effects of Erector Spinae Plane Block in Terms of Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: A Meta-Analysis of Randomized Controlled Trials
Chang‐Hoon Koo, Jin‐Young Hwang, Hyun‐Jung Shin, Jung‐Hee Ryu
SJR Q1Journal of Clinical MedicineOA

Ultrasound-guided erector spinae plane block (ESPB), a recent regional analgesic technique, has been used to manage acute pain after surgery. The aim of this meta-analysis is to identify the benefits of ESPB in patients undergoing laparoscopic cholecystectomy (LC). The authors searched PubMed, EMBASE, CENTRAL, CINAHL, and Web of Science to identify all randomized controlled trials (RCTs) evaluating the effects of ESPB on postoperative pain after LC. Primary outcome was defined as 24 h cumulative

SurgeryMedicine
7
Article|39 citations·2016
Influence of high-dose intraoperative remifentanil with intravenous ibuprofen on postoperative morphine consumption in patients undergoing pancreaticoduodenectomy: a randomized trial
Chang‐Hoon Koo, Youn Joung Cho, Deok Man Hong, Yunseok Jeon, Tae Kyong Kim
SJR Q1Journal of Clinical Anesthesia
SurgeryMedicine
8
Review|35 citations·2019
The Effects of Intraoperative Inspired Oxygen Fraction on Postoperative Pulmonary Parameters in Patients with General Anesthesia: A Systemic Review and Meta-Analysis
Chang‐Hoon Koo, Eun Young Park, Sunyoung Lee, Jung‐Hee Ryu
SJR Q1Journal of Clinical MedicineOA

High intraoperative inspired oxygen concentration is applied to prevent desaturation during induction and recovery of anesthesia. However, high oxygen concentration may lead to postoperative pulmonary complications. The purpose of this study is to compare the postoperative pulmonary parameters according to intraoperative inspired oxygen fraction in patients undergoing general anesthesia. We identified all randomized controlled trials investigating postoperative differences in arterial gas exchan

Pulmonary and Respiratory MedicineMedicine
9
Article|27 citations·2020
Lidocaine vs. Other Local Anesthetics in the Development of Transient Neurologic Symptoms (TNS) Following Spinal Anesthesia: A Meta-Analysis of Randomized Controlled Trials
Chang‐Hoon Koo, Hyun-Jung Shin, Sung‐Hee Han, Jung‐Hee Ryu
SJR Q1Journal of Clinical MedicineOA

The use of lidocaine in spinal anesthesia may increase the risk of transient neurological symptoms (TNS) according to previous meta-analyses. However, the previous meta-analyses lacked data on some other local anesthetics and thus, more evaluations are still needed to compare the effect of lidocaine on the development of TNS. The objective of this study was to compare the risk of TNS according to lidocaine versus other local anesthetics in patients undergoing spinal anesthesia. A total of 39 ran

SurgeryMedicine
10
Review|26 citations·2019
Anesthetic considerations for urologic surgeries
Chang‐Hoon Koo, Jung‐Hee Ryu
SJR Q1Korean journal of anesthesiologyOA

Urologic surgeries are widely performed, and the cases have increased owing to the fact that the elderly population is growing. The narrow and limited surgical space is a challenge in performing most urologic surgeries. Additionally, the elderly population is exposed to the risk of perioperative complications; therefore, a comprehensive understanding and approach are required to provide optimized anesthesia during surgery. We have searched the literature on anesthesia for urologic surgeries and

SurgeryMedicine
11
Review|25 citations·2021
The effects of intraoperative magnesium sulfate administration on emergence agitation and delirium in pediatric patients: A systematic review and meta‐analysis of randomized controlled trials
Chang‐Hoon Koo, Bon‐Wook Koo, Jiwon Han, Hun‐Taek Lee, Dongsik Lim, Hyun‐Jung Shin
SJR Q2Pediatric Anesthesia

BACKGROUND: The role of intraoperative magnesium for the prevention of emergence agitation or delirium is unclear as there have been conflicting results reported by several randomized controlled trials. AIMS: The aim of this study was to investigate the effect of magnesium sulfate on emergence agitation or emergence delirium in pediatric patients. METHODS: Electronic databases, including PubMed, EMBASE, CENTRAL, CINAHL, Scopus, and Web of Science, were searched to identify studies which evaluate

Critical Care and Intensive Care MedicineMedicine
12
Article|23 citations·2021
Neurotoxic Effects of Local Anesthetics on Developing Motor Neurons in a Rat Model
Chang‐Hoon Koo, Jiseok Baik, Hyun‐Jung Shin, Jin‐Hee Kim, Jung‐Hee Ryu, Sung‐Hee Han
SJR Q1Journal of Clinical MedicineOA

Neurotoxic effects of local anesthetics (LAs) on developing motor neurons have not been documented. We investigated the neurotoxic effects of LAs on developing motor neurons in terms of cell viability, cytotoxicity, reactive oxygen species (ROS), and apoptosis. Embryonic spinal cord motor neurons were isolated from Sprague-Dawley rat fetuses and exposed to one of the three LAs-lidocaine, bupivacaine, or ropivacaine-at concentrations of 1, 10, 100, or 1000 µM. The exposure duration was set to 1 o

SurgeryMedicine
13
Article|20 citations·2018
Comparison between the effects of deep and moderate neuromuscular blockade during transurethral resection of bladder tumor on endoscopic surgical condition and recovery profile: a prospective, randomized, and controlled trial
Chang‐Hoon Koo, Seung Hyun Chung, B. G. Kim, Baehyun Min, S. C. Lee, Ah‐Young Oh, Young‐Tae Jeon, Jung‐Hee Ryu
SJR Q1World Journal of Urology
Anesthesiology and Pain MedicineMedicine
14
Article|15 citations·2020
Factors associated with a 30-day unplanned readmission after elective spine surgery: a retrospective cohort study
Tak Kyu Oh, Jung‐Hee Ryu, Ji-W on Han, Chang‐Hoon Koo, Young-Tae Jeon
SJR Q1European Spine Journal
Cardiology and Cardiovascular MedicineMedicine
15
Review|15 citations·2019
The Effect of Perioperative Intravenous Iron on Hemoglobin in Surgical Patients: A Meta-Analysis
Chang‐Hoon Koo, Hyun-Jung Shin, Hyun-Hee Cho, Jung‐Hee Ryu
SJR Q1Journal of Surgical Research
BiochemistryMedicine

Research Areas

SurgeryAnesthesiology and Pain MedicinePulmonary and Respiratory MedicineCardiology and Cardiovascular MedicineBiochemistryNephrology

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