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Chang Hun Huh

Seoul National University · Medicine

About the Lab

Professor Chang Hun Huh's research lab specializes in dermatological and aesthetic medicine, focusing on innovative, non-invasive or minimally invasive treatments for skin and hair disorders. Key research directions include optimizing drug delivery for melasma using iontophoresis, evaluating high-dose finasteride and dutasteride for androgenetic alopecia, and exploring advanced energy-based and liposuction techniques for benign skin tumors like lipomas. The lab emphasizes clinical efficacy, patient safety, and improving treatment outcomes through targeted, evidence-based approaches.

melasmaandrogenetic alopeciadrug deliveryliposuctionfinasteride

Research Overview

Papers
253
Total Citations
5,578
Papers (5y)
43
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
43total
2022
2023
2024
2025
2026
Citations per year (5y)
322total
20222023202420252026

Selected Papers

15
1
Article|110 citations·2003
A Randomized, Double-Blind, Placebo-Controlled Trial of Vitamin C Iontophoresis in Melasma
Chang‐Hun Huh, K. A. Seo, Jeyoung Park, Jeong-Gu Lim, Hee-Chul Eun, Kyung-Chan Park
SJR Q1Dermatology

BACKGROUND: Vitamin C is known to both inhibit melanin formation and reduce oxidized melanin. However, vitamin C does not easily penetrate the skin. In this study, vitamin C iontophoresis was employed in order to enhance vitamin C penetration. OBJECTIVE: The purpose of this study was to evaluate the efficacy of vitamin C iontophoresis for melasma patients. METHODS: Twenty-nine females with melasma were enrolled. For iontophoresis, a vitamin C solution was applied to one side of the face, while d

DermatologyMedicine
2
Article|87 citations·2010
5 mg/day finasteride treatment for normoandrogenic Asian women with female pattern hair loss
JH Yeon, JY Jung, JW Choi, Beom Joon Kim, Sang Woong Youn, Park Kc, Chang‐Hun Huh
SJR Q1Journal of the European Academy of Dermatology and VenereologyOA

BACKGROUND: Various treatments have been attempted for female pattern hair loss (FPHL), including topical minoxidil, oral antiandrogen and finasteride. But, there is no consensus on the standard treatment options. Clinical efficacy of finasteride in treating FPHL is still in controversy, but there is a tendency to high dose finasteride, which is more effective than lower dose. OBJECTIVES: The purpose of this study was to evaluate the clinical efficacy of high dose (5 mg/day) oral finasteride in

UrologyMedicine
3
Article|59 citations·2008
Combination therapy of cyclosporine and methylprednisolone on severe alopecia areata
Beom Joon Kim, Seong Uk Min, Kui Young Park, Jung Won Choi, Sung Wook Park, Sang Woong Youn, Kyoung Chan Park, Chang‐Hun Huh
SJR Q1Journal of Dermatological Treatment

Although limited by its uncontrolled character, this study shows that combination therapy with cyclosporine and methylprednisolone may be a useful treatment for severe AA.

UrologyMedicine
4
Article|57 citations·2010
Low-dose 1064-nm Q-switched Nd:YAG laser for the treatment of melasma
Mira Choi, Jee Woong Choi, Sun‐Young Lee, Sun-Young Choi, Hye-Jin Park, Kyoung‐Chan Park, Sang Woong Youn, Chang‐Hun Huh
SJR Q1Journal of Dermatological Treatment

Low-dose 1064-nm QSNYL appears to be an effective treatment modality for melasma.

DermatologyMedicine
5
Article|56 citations·2014
Effect of dutasteride 0.5 mg/d in men with androgenetic alopecia recalcitrant to finasteride
Jae Yoon Jung, Je Ho Yeon, Jee Woong Choi, Soon‐Hyo Kwon, Beom Joon Kim, Sang Woong Youn, Kyoung Chan Park, Chang‐Hun Huh
SJR Q1International Journal of DermatologyOA

BACKGROUND: Finasteride at a dose of 1 mg/d has been reported to show no significant improvement in 30-50% of patients with androgenetic alopecia (AGA). Dutasteride, a dual inhibitor of both type I and type II 5 alpha-reductase, inhibits the conversion of testosterone to dihydrotestosterone, which is the key contributor of AGA. MATERIALS AND METHODS: Our aim is to evaluate clinical efficacy and tolerability of dutasteride in men with AGA who do not show clinical improvement to the conventional f

UrologyMedicine
6
Article|52 citations·2007
Treatment of lipomas assisted with tumescent liposuction
CW Choi, BJ Kim, SE Moon, Sang Woong Youn, K. -C. Park, Chang‐Hun Huh
SJR Q1Journal of the European Academy of Dermatology and Venereology

BACKGROUND: Lipoma is a common soft-tissue tumour of mature fat cells. Although surgical excision is effective, treatments that are less invasive and not associated with disfigurement of scar would be ideal for the treatment of lipomas. Recently, tumescent liposuction has been used for the treatment of lipomas. OBJECTIVE: To evaluate the efficacy of tumescent liposuction in lipoma treatment, we reviewed our experience of lipoma treatment by tumescent liposuction. METHODS: A total of 21 patients

SurgeryMedicine
7
Article|43 citations·2010
Objective and non‐invasive evaluation of photorejuvenation effect with intense pulsed light treatment in Asian skin
J‐W Shin, D‐H Lee, S‐Y Choi, J‐I Na, K. C. Park, S‐W Youn, Chang‐Hun Huh
SJR Q1Journal of the European Academy of Dermatology and Venereology

BACKGROUND: Intense pulsed light (IPL) has been widely used for photorejuvenation. Although previous literature has shown clinical effectiveness of IPL treatments on cutaneous photoaging, the associated changes in the biophysical properties of the skin following IPL treatments have not been fully elucidated. OBJECTIVE: The aim of this study was to evaluate changes in skin biophysical properties in patients with photoaging after IPL treatments, using non-invasive, objective skin measuring devices

DermatologyMedicine
8
Article|34 citations·2018
Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system
Jung Won Shin, Euy‐Hyun Chung, Moon Bum Kim, Tae‐Ook Kim, Woo‐Il Kim, Chang‐Hun Huh
SJR Q1The Journal of DermatologyOA

Finasteride 1 mg is considered to be the standard treatment method for male androgenetic alopecia (AGA). However, there have only been a few studies investigating its long-term efficacy. Moreover, its effect on various types of AGA remains unknown. In this study, the authors investigated the 5-year efficacy of finasteride 1 mg in Korean men with AGA and analyzed the changes in hair growth according to the distribution of hair loss. The medical records of male AGA patients who were treated with o

UrologyMedicine
9
Article|32 citations·2013
Efficacy and Safety of a Novel Botulinum Toxin Type A Product for the Treatment of Moderate to Severe Glabellar Lines: A Randomized, Double-Blind, Active-Controlled Multicenter Study
Chong Hyun Won, Hyung M. Lee, Woo Shun Lee, Hoon Kang, Beom Joon Kim, Won S. Kim, Ju Hee Lee, Dong Hun Lee, Chang‐Hun Huh
SJR Q2Dermatologic SurgeryOA

NBoNT is equally as effective as OBoNT for the treatment of glabellar frown lines. Both toxins were well tolerated.

NeurologyMedicine
10
Article|30 citations·2006
Photoepilation Results of Axillary Hair in Dark-Skinned Patients by IPL: A Comparison Between Different Wavelength and Pulse Width
Jong Hee Lee, Chang‐Hun Huh, Ho Joon Yoon, Kwang Hyun Cho, Jin Ho Chung
SJR Q2Dermatologic Surgery

An IPL source removing 45 nm of the emitted spectra and applying a longer pulse width was found to provide a safer and more effective means of photo-epilation in Asian patients.

DermatologyMedicine
11
Article|29 citations·2014
Characteristics of robotically harvested hair follicles in Koreans
Jung Won Shin, Soon‐Hyo Kwon, Sung Ae Kim, Joo Yong Kim, Jung Im Na, Kyoung Chan Park, Chang‐Hun Huh
SJR Q1Journal of the American Academy of DermatologyOA

The robotic system qualifies for use in hair restoration surgery. It efficiently harvests not only single hairs but multiple hairs as well.

UrologyMedicine
12
Article|28 citations·2019
Efficacy of liposome‐encapsulated 4‐n‐butylresorcinol and resveratrol cream in the treatment of melasma
Soon‐Hyo Kwon, Ji Hoon Yang, Jung Won Shin, Kyoung‐Chan Park, Chang‐Hun Huh, Jung‐Im Na
SJR Q2Journal of Cosmetic Dermatology

BACKGROUNDS: We previously reported the efficacy of 0.1% 4-n-butylresorcinol (4nBR) cream in the treatment melasma and synergistic effect of 4nBR and resveratrol (RSV) to inhibit melanogenesis in vitro. AIMS: To evaluate efficacy and safety of a cream which contains liposome-encapsulated 4nBR and RSV in the treatment of melasma. PATIENTS/METHODS: A total of 21 female patients with melasma were treated with the cream for 4 weeks. At baseline, week 2, and week 4, melanin index (MI) of the lesional

DermatologyMedicine
13
Article|21 citations·2019
The efficacy and safety of microneedle monopolar radiofrequency for the treatment of periorbital wrinkles
Soon‐Hyo Kwon, Ji‐Young Choi, Gun Young Ahn, Woo Sun Jang, Jung Won Shin, Jung‐Im Na, Kyoung‐Chan Park, Chang‐Hun Huh
SJR Q1Journal of Dermatological Treatment

We demonstrated the efficacy and safety of the microneedle monopolar RF device in treating periorbital wrinkles. The LMN was superior to the SMN in reducing VISIA wrinkle score.

DermatologyMedicine
14
Article|19 citations·2023
Wearable and Wavelength-Tunable Near-Infrared Organic Light-Emitting Diodes for Biomedical Applications
Eun‐Hae Cho, Hye‐Ryung Choi, Yongjin Park, So Yeong Jeong, Young Jin Song, Yong Ha Hwang, Junwoo Lee, Yün Chi, Sheng‐Fu Wang, Yongmin Jeon, Chang‐Hun Huh, Kyung Cheol Choi
SJR Q1ACS Applied Materials & Interfaces

Near-infrared organic light-emitting diodes (NIR OLEDs) have significant potential for wearable phototherapeutic applications because of the unique properties of the OLEDs, including their free-form electronics and the excellent biomedical effects of NIR emission. In spite of their tremendous promise, given that the majority of NIR OLEDs in previous research have relied on the utilization of an intrinsically brittle indium tin oxide (ITO) electrode, their practicality in the field of wearable el

Biomedical EngineeringEngineering
15
Article|19 citations·2023
A wearable OLED medical device for enhanced cutaneous wound healing and patient comfort: revolutionizing dermatology
Yongjin Park, Hye‐Ryung Choi, Jung Won Shin, Chang‐Hun Huh, Kyung Cheol Choi
SJR Q1Journal of Information DisplayOA

Integrating organic light-emitting diodes (OLEDs) with light therapy can significantly advance biomedical applications by offering non-invasive, precise, and customizable treatments. Developing innovative device designs and performing cellular tests is essential to assess the safety and effect of OLED-based light therapies in dermatology. As such, a wearable OLED medical device prototype has been created for easy attachment to the body, ensuring consistent exposure to skin injuries due to its co

Radiology, Nuclear Medicine and ImagingMedicine

Research Areas

DermatologyUrologySurgeryCell BiologyOncologyEpidemiology

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