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Chang Kyu Lee

Yonsei University · Medicine

About the Lab

Professor Chang Kyu Lee's research lab specializes in cerebrovascular and neurosurgical disorders, with a primary focus on aneurysmal subarachnoid hemorrhage (SAH), particularly in poor-grade patients (Hunt and Hess Grade IV/V). The lab investigates surgical and medical management strategies to improve outcomes, evaluates complications such as delayed cerebral ischemia and post-dural puncture headache, and explores innovative techniques like endovascular aneurysm occlusion and microsurgical cysto-cisternal shunting. The research also extends to experimental models of inflammatory arthritis to assess the therapeutic potential of antioxidants like vitamin E.

aneurysmal subarachnoid hemorrhagepoor-grade SAHcerebral aneurysmpostdural puncture headacheneurosurgical outcomes

Research Overview

Papers
112
Total Citations
838
Papers (5y)
15
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
15total
2016
2019
2020
2021
2023
Citations per year (5y)
192total
20162019202020212023

Selected Papers

15
1
Review|77 citations·1999
Recanalization of completely thrombosed giant aneurysm: case report
Kyu Chang Lee, Kyu Chang Lee, Jin Yang Joo, Kyu Sung Lee, Kyu Sung Lee, Yong Sam Shin
Surgical NeurologyOA
NeurologyMedicine
2
Review|44 citations·2008
Surgery for distal anterior cerebral artery aneurysms
Jae Whan Lee, Kyu Chang Lee, Yong Bae Kim, Seung Kon Huh
Surgical NeurologyOA
NeurologyMedicine
3
Article|21 citations·1997
Management of Poor-grade Patients with Ruptured Intracranial Aneurysm.
Kyu Chang Lee, Seung Huh, Hyeon Seon Park, Yong Sam Shin, Kyu Sung Lee
SJR Q3The Keio Journal of MedicineOA

To formulate treatment strategies for poor-grade patients after aneurysmal subarachnoid hemorrhage (SAH), medical records were analyzed for 166 patients who were in Hunt and Hess Grade IV or V among 588 consecutive cases with ruptured intracranial aneurysm admitted during the past 5 years. Causes of unfavorable outcome (poor or dead) in those 166 patients were evaluated to improve the management outcome. Overall management results of the 166 poor-grade patients were favorable (good or fair) in 7

NeurologyMedicine
4
Article|21 citations·2003
Surgery for posterior communicating artery aneurysms
Kyu Chang Lee, Kyu Sung Lee, Yong Sam Shin, Jae Whan Lee, Su Kyoung Chung
Surgical NeurologyOA
NeurologyMedicine
5
Article|5 citations·2010
Abdominal compartment syndrome occurring due to uterine perforation during a hysteroscopy procedure
Kyu Chang Lee, Hye Young Kim, Myeong-Jong Lee, Jai Won Koo, Jeong Ae Lim, Seong‐Hyop Kim
SJR Q2Journal of Anesthesia
Pulmonary and Respiratory MedicineMedicine
6
Article|4 citations·1982
Surgical Treatment of Anterior Communicating Artery Aneurysms
Kyu Chang Lee, Kyu Sung Lee, Sang Sup Chung, Young Soo Kim, Joong Uhn Choi
SJR Q2Yonsei Medical Journal
NeurologyMedicine
7
Article|3 citations·1997
Management of arteriovenous malformations: part I
Kyu Chang Lee
Surgical Neurology
NeurologyMedicine
8
Article|2 citations·2005
Development of Cerebrovascular Surgery in Korea
Kyu Chang Lee
Korean Journal of Cerebrovascular Surgery
EpidemiologyMedicine
9
Article|1 citations·1993
Fatal Rupture of a Giant Carotid Aneurysm Following High-flow Bypass and Endovascular Occlusion
Kyu Chang Lee, Dong Ik Kim
Surgery for Cerebral StrokeOA

A case of fatal rupture of a giant internal carotid aneurysm is reported, which occurred after an extracranial to intracranial (EC-IC) bypass surgery combined with occlusion of the proximal internal carotid artery (ICA) by detachable balloons. A 65-year-old woman presented with progressive visual deterioration due to an unruptured giant aneurysm at the supraclinoid segment of the ICA. Since the patient did not tolerate a balloon occlusion test of the ICA, saphenous vein graft was undertaken betw

NeurologyMedicine
10
Article|1 citations·1998
Current Status of Management for Poor-grade Patients with Ruptured Intracranial Aneurysm
Kyu Chang Lee
Surgery for Cerebral StrokeOA

To establish a management strategies for poor-grade patients after aneurysmal subarachnoid hemorrhage (SAH), medical records were analyzed for 166 patients who were in Hunt and Hess Grade IV or V among 588 consecutive cases with ruptured intracranial aneurysm admitted during the past 5 years. Causes of unfavorable outcome (poor or dead) in those 166 patients were evaluated to improve the management outcome.Overall management results of the 166 poor-grade patients were favorable (good or fair) in

NeurologyMedicine
11
Book Chapter|1 citations·2019
Microsurgical Treatment of Intracranial Arachnoid Cysts
Kyu Chang Lee

Intracranial arachnoid cysts are benign, thin-walled cysts characteristically lying in the arachnoid, filled with clear fluid, located in general near primary fissure of the cerebral cortex and cerebellum, and associated with varying degrees of cerebral tissue loss by compression. Although cystoperitoneal shunt surgery is indicated in some cases with the midline or the posterior fossa cysts, the rest of the arachnoid cysts are best managed by the radical microsurgical technique of establishing a

Cellular and Molecular NeuroscienceNeuroscience
12
Article|1 citations·2001
Commentary
Kyu Chang Lee
Surgical Neurology
NeurologyMedicine
13
Article|1 citations·2002
The Role of Neurosurgeons in the Era of Endovascular Treatment of Cerebral Aneurysms
Kyu Chang Lee
SJR Q1Neurologia medico-chirurgicaOA
NeurologyMedicine
14
Article|1 citations·2015
Evaluation of Incidence of Post-Dural Puncture Headache with Maintenance of Sitting Position Immediately After Spinal Anesthesia
Kyu Chang Lee
Journal of AnesthesiologyOA

<i>Background: </i>In spinal saddle anesthesia, maintaining the sitting position for 3–5 min, to allow for the descent of the injected drug after lumbar dural puncture, minimizes side effects such as blood pressure reduction. However, it also increases cerebrospinal fluid leakage due to the hydrostatic pressure. We investigated the effects of the maintenance of the sitting position after spinal anesthesia on the development of postdural puncture headache (PDPH). <i>Methods: </i>We reviewed all d

SurgeryMedicine
15
Article|1 citations·1991
Acute Pulmonary Edema Following Esophagoscopy: A case report
Kyu Chang Lee, Jin Kyung Lee, Jung Ho Kim, Sung Jong Kim, Ye Chull Lee
SJR Q1Korean Journal of AnesthesiologyOA
SurgeryMedicine

Research Areas

NeurologySurgeryPulmonary and Respiratory MedicineEndocrinology, Diabetes and MetabolismCellular and Molecular NeuroscienceAnesthesiology and Pain Medicine

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