Chang Kyu Sung
Seoul National University · Medicine
About the Lab
Professor Chang Kyu Sung's research lab specializes in medical imaging and interventional radiology, focusing on improving diagnostic accuracy in renal diseases through advanced imaging techniques such as CT and Doppler ultrasound. The lab investigates vascular hemodynamics, tumor characterization (particularly angiomyolipoma and renal cell carcinoma), and image-guided ablation therapies like irreversible electroporation. It also explores multimodal molecular imaging agents for stem cell tracking, combining MRI and optical imaging for enhanced visualization. The lab emphasizes the clinical translation of imaging biomarkers and computational models to optimize patient outcomes.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15BACKGROUND: Angiomyolipoma (AML) with minimal fat may mimic renal cell carcinoma (RCC) and is difficult to distinguish from RCC with imaging studies alone. Precise diagnostic strategies have been explored to discern AML with minimal fat from RCC. PURPOSE: To compare the morphological and enhancement features of AML with minimal fat with those of size-matched RCC on computed tomography (CT). MATERIAL AND METHODS: Our study included 143 pathologically proved renal tumors (29 AML with minimal fat:
MNP@SiO(2)(RITC)-PEG can be a useful contrast agent for stem cell imaging, which is suitable for a bimodal detection by MRI and optical imaging.
Resistance and compliance can alter the Doppler waveforms independently. The pulse rate is an extrinsic factor that also influences the RI. The compliance and distal resistance, as well as proximal resistance, influence the pulsus tardus and parvus phenomenon.
Irreversible electroporation has clinically been used to treat various types of cancer. A plan on how to apply irreversible electroporation before practicing is very important to increase the ablation area and reduce the side effects. Several electrical models have been developed to predict the ablation area with applied electric energy. In this experiment, the static relationship between applied electric energy and ablated area was mathematically and experimentally investigated at 10 hours afte
The urine CT attenuation ratio is a simple and reliable indicator with which to detect and lateralize significant RAS and is a useful adjunct to helical CTA.
This simulation study using an electrical circuit model led to a better understanding of the renal arterial Doppler waveform and the RI, which may be useful for interpreting Doppler findings in various clinical settings.
The purpose of this study was to identify the ultrasonographic findings that reflected disease severity in patients with autosomal dominant polycystic kidney disease (ADPKD). In 72 patients with ADPKD, resistive indices (RIs) and the severity of ultrasonographic morphologic abnormalities, such as renal severity index (RSI), modified RSI and the sum of bilateral renal size, were measured and correlated with clinical and laboratory findings including the presence of hypertension and serum creatini
Impairment caused by Doppler frequency shift and harsh channel condition distinguish underwater acoustic communications from radio communications. Slow speed of acoustic waves produces relatively high Doppler shift and result in expansion or compression in time samples, which is known as Doppler scaling. In particular, the Doppler scaling causes significant carrier frequency offset (CFO) in orthogonal frequency division modulation (OFDM). To compensate the CFO, it is essential to resample signal
Unlike necrosis by thermal ablation, irreversible electroporation (IRE) is known to induce apoptosis by disrupting plasma membrane integrity with electric pulses while preserving the structure of blood vessels and bile ducts in liver tissue without a heat sink effect. This study aimed to investigate thermal damage and histopathological effects in the porcine liver by high-frequency electric pulses (5 kHz) which is much higher than the widely used 1 Hz. The electric field and thermal distribution
ABSTRACT The therapeutic potential of photobiomodulation (PBM) for Alzheimer's disease (AD) was evaluated by examining β‐amyloid accumulation, microglial activation, and memory function. Mitochondrial delayed luminescence (m‐DL), an indirect mitochondrial marker, was measured by irradiating 2 J/cm 2 of 808 nm near‐infrared light to the exposed brain surface of anesthetized 5XFAD mice. Based on m‐DL findings, behavioral PBM was applied transcranially to the intact scalp using the same fluence at
Research Areas
Dive deeper into Chang Kyu Sung's research on Nubint
Open this lab's papers in the app to read with AI, summarize, and cite in your writing.