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Chang Sin Kim

Yonsei University · Medicine

About the Lab

Professor Chang Sin Kim's research lab specializes in pediatric and congenital cardiovascular diseases, with a focus on advanced echocardiographic imaging, particularly speckle tracking echocardiography, to assess myocardial mechanics in children. The lab investigates the hemodynamic changes associated with aging and disease states such as aortic regurgitation, ventricular septal defects, and rare arrhythmias like idiopathic ventricular fibrillation and early repolarization syndrome. They also explore interventional and surgical outcomes in high-risk pediatric and young adult patients, including those with complex conditions like Behçet syndrome and pulmonary interstitial emphysema in extremely low birth weight infants. Their work bridges diagnostic imaging, interventional cardiology, and clinical outcomes in congenital and inherited heart diseases.

speckle tracking echocardiographypediatric cardiomyopathycongenital heart diseasearrhythmia syndromesinterventional cardiology

Research Overview

Papers
12
Total Citations
15
Papers (5y)
12
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2016
2023
2024
2025
2026
Citations per year (5y)
15total
20162023202420252026

Selected Papers

12
1
Article|6 citations·2016
Myocardial Rotation and Torsion in Child Growth
Chang Sin Kim, Sora Park, Lucy Youngmin Eun
Journal of Cardiovascular UltrasoundOA

BACKGROUND: The speckle tracking echocardiography can benefit to assess the regional myocardial deformations. Although, previous reports suggested no significant change in left ventricular (LV) torsion with aging, there are certain differences in LV rotation at the base and apex. The purpose of this study was to evaluate the change and relationship of LV rotation for torsion with aging in children. METHODS: Forty healthy children were recruited and divided into two groups of twenty based on whet

Cardiology and Cardiovascular MedicineMedicine
2
Article|3 citations·2016
A Case of Pulmonary Interstitial Emphysema Treated by Percutaneous Catheter Insertion in Extremely Low Birth Weight Infant
이순민, 김창신, 신정은, 은호선, 박민수, 박국인, 남궁란, 이성수, 윤춘식
http://ymj.kr/DOIx.php?id=10.3349/ymj.2016.57.6.1523

The pulmonary interstitial emphysema (PIE) is a life-threatening illness in premature infants with mechanical ventilation. While most are managed conservatively, decompression would be necessary. Here, we report the first case of PIE treated by percutaneouscatheter insertion in an extremely low birth weight (ELBW) infant in Korea. The patient, born with 660 g in 23+2 weeks of gestation,showed PIE in left lower lung on postnatal day 12. Percutaneous catheter insertion was performed on postnatal d

3
Article|3 citations·2025
Arrhythmic Risk and Clinical Features in Catecholaminergic Polymorphic Ventricular Tachycardia: Results From a Multicenter Study in Korea
Min-Jung Cho, Mi Kyoung Song, So Yun Jun, Hye Won Kwon, Young Hye Ryu, Seung-Min Baek, Jung‐Hye Kwon, Ah Young Kim, Ja Kyoung Yoon, Chang Sin Kim, Mi Jin Kim, Jae Suk Baek
SJR Q2The American Journal of Cardiology
Cardiology and Cardiovascular MedicineMedicine
4
Article|1 citations·2016
Myocardial Rotation and Torsion in Child Growth
김창신, 박소라, 은영민
http://dx.doi.org/10.4250/jcu.2016.24.3.223

Background: The speckle tracking echocardiography can benefit to assess the regional myocardial deformations. Although,previous reports suggested no significant change in left ventricular (LV) torsion with aging, there are certain differences in LV rotationat the base and apex. The purpose of this study was to evaluate the change and relationship of LV rotation for torsion withaging in children. Methods: Forty healthy children were recruited and divided into two groups of twenty based on whether

5
Article|1 citations·2025
Patient with Behçet Syndrome with Subaortic Pseudoaneurysm Who Underwent the Bentall Operation Showed Improvement after Medical Treatment
Hanbyul Lee, Chang Sin Kim, Jo Won Jung, Han Ki Park, Jong Gyun Ahn
SJR Q2Yonsei Medical JournalOA

Aortic regurgitation (AR) in children is usually caused by congenital valve anomalies, and Behçet syndrome (BS) can be suspected in cases of isolated AR. Patients with BS undergoing aortic valve surgery due to aortic valve invasion have a high risk of complications, such as leakage around the valve and dehiscence. Cardiovascular involvement occurs in 7%-46% of adult patients with BS and is the main cause of mortality; however, its prevalence is unclear and rare in children. A 12-year-old boy was

OphthalmologyMedicine
6
Article|1 citations·2024
Predictive Scoring System for Spontaneous Closure of Infant Ventricular Septal Defect: The P-VSD Score
Ah Young Kim, Nuri Tchah, Ching-yu Lin, Jung Min Park, Wongi Woo, Chang Sin Kim, Se Yong Jung, Jae Young Choi, Jo Won Jung
SJR Q2Pediatric Cardiology
EpidemiologyMedicine
7
Article|0 citations·2023
Transcatheter Closure of The Ventricular Septal Defect in Patients With Multiple Comorbidities
Chang Sin Kim, Ah Young Kim, Se Yong Jung, Jae Young Choi, Jo Won Jung
CardioMetabolic Syndrome JournalOA

A ventricular septal defect (VSD) is the most prevalent congenital heart disease.Some patients who were watched without surgery when they were young need surgery as they age.The surgical approach is the standard treatment and suitable for young age, but it can be complex in these patients of advanced age with multiple risk factors including cardiometabolic syndrome.We present two cases of transcatheter VSD closure that were successful in patients in their 60s who had a variety of comorbidities.F

EpidemiologyMedicine
8
Article|0 citations·2026
Clinical manifestations and outcomes of idiopathic ventricular fibrillation and early repolarization syndrome in adolescents: A multicenter cohort study
Seung Min Baek, Jae Suk Baek, Joowon Lee, Ja Kyoung Yoon, Hye Won Kwon, Young Hye Ryu, So Yon Jun, Mi Jin Kim, Ah Young Kim, Chang Sin Kim, Ji Eun Ban, June Huh
SJR Q1Heart Rhythm O2OA

BACKGROUND Idiopathic ventricular fibrillation (IVF) and early repolarization syndrome (ERS) are rare but potentially life-threatening arrhythmias. Their clinical distinction is often challenging and prognostic factors remain unclear, particularly in adolescents. OBJECTIVE This study compared clinical outcomes and electrocardiographic characteristics of adolescents with IVF and ERS to identify disease-specific prognostic factors. METHODS Patients diagnosed with IVF or ERS between 2000 and 2022 w

Cardiology and Cardiovascular MedicineMedicine
9
Article|0 citations·2026
Electrophysiological Features and Catheter Ablation for Supraventricular Tachyarrhythmias in Patients with Fontan Circulation: A Multicenter Study
J S Uhm, Mi Kyoung Song, Ji‐Eun Ban, Seung Min Baek, TaeHyun Hwang, Seunghoon Cho, Hanjin Park, Daehoon Kim, Hee Tae Yu, T H Kim, Boyoung Joung, Hui-Nam Pak
medRxivOA

Abstract Background Patients with Fontan circulation experience significant morbidity from supraventricular tachyarrhythmias (SVTs). However, the electrophysiological features of SVT and the efficacy and safety of catheter ablation in patients with Fontan circulation are poorly understood. This study aimed to elucidate the electrophysiological features of SVT and evaluate the efficacy and safety of catheter ablation in patients with Fontan circulation. Methods Forty-nine patients (age, 29.2±10.0

Cardiology and Cardiovascular MedicineMedicine
10
Article|0 citations·2025
Longitudinal changes in ventricular function and atrioventricular valve failure following cardiac morphology after Fontan procedure
Ah Young Kim, Jaemin Byun, Ji Eun Hwang, Wongi Woo, Chang Sin Kim, Se Yong Jung, Lucy Youngmin Eun, Jae Young Choi, Yu Rim Shin, Jo Won Jung, Han Ki Park
SJR Q2Journal of Thoracic DiseaseOA

Fontan patients with long-term follow-up showed a progressive decline in ventricular and AVV function. Dominant RV, TV and common AVV were prognostic factors for predicting AVV failure. Further studies are warranted to explore and validate these findings.

EpidemiologyMedicine
11
Article|0 citations·2026
Prospective Midterm Outcomes of the PULSTA Self-Expandable Transcatheter Pulmonary Valve: The PULSTA CE Approval Study
Sang Yun Lee, Gi Beom Kim, Mário Carminati, Luca Giugno, Ahmet Çelebi, İlker Kemal Yücel, Andreas Eicken, Peter Ewert, Stanimir Georgiev, Jae Young Choi, Chang Sin Kim, Federico Gutiérrez‐Larraya
SJR Q1Circulation Cardiovascular Interventions

BACKGROUND: Patients with congenital or acquired right ventricular outflow tract dysfunction frequently require pulmonary valve replacement and are exposed to repeated surgical interventions due to prosthetic valve degeneration. The PULSTA self-expanding transcatheter pulmonary valve was designed to address a broad spectrum of native and surgically repaired right ventricular outflow tract anatomies. This study reports the midterm safety, hemodynamic performance, and durability outcomes of the pr

EpidemiologyMedicine
12
Preprint|0 citations·2025
Arrhythmic Risk and Clinical Features in Catecholaminergic Polymorphic Ventricular Tachycardia: Results from a Multicenter Study in Korea
Min-Jung Cho, Mi Kyoung Song, So Yun Jun, Hye Won Kwon, Young Hye Ryu, Seung Min Baek, Jung‐Hye Kwon, Ja Kyoung Yoon, Ah Young Kim, Chang Sin Kim, Mi Jin Kim, Jae Suk Baek
SSRN Electronic JournalOA
Cardiology and Cardiovascular MedicineMedicine

Research Areas

Cardiology and Cardiovascular MedicineEpidemiologyOphthalmology

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