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Cheolhyun Park

Sungkyunkwan University · Medicine

About the Lab

Professor Cheolhyun Park's research lab specializes in the intersection of metabolic health, musculoskeletal disorders, and systemic inflammation, with a focus on sarcopenia, obesity, and their implications in chronic diseases. The lab investigates the relationships between body composition, inflammatory markers like hs-CRP, and clinical outcomes such as lung function, diabetes-related spinal disorders, and dysphagia. Utilizing large-scale national health databases and clinical assessments, the lab emphasizes population-based, observational studies to uncover sex-specific and age-related patterns in metabolic and musculoskeletal health. Their work also explores predictive biomarkers and clinical tools—such as HRM parameters—for early detection of conditions like aspiration pneumonia in vulnerable populations.

sarcopeniabody compositioninflammationdysphagiametabolic health

Research Overview

Papers
80
Total Citations
814
Papers (5y)
39
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
39total
2021
2022
2023
2024
2025
Citations per year (5y)
343total
20212022202320242025

Selected Papers

15
1
Article|87 citations·2018
Relationship between skeletal muscle mass and lung function in Korean adults without clinically apparent lung disease
Chul‐Hyun Park, Youbin Yi, Jong Geol, Yong‐Taek Lee, Kyung Jae Yoon
SJR Q3MedicineOA

Previous studies have demonstrated that low skeletal muscle mass is related to decreased lung function in patients with chronic obstructive pulmonary disease. However, there is little information about the relationship between skeletal muscle mass and lung function in asymptomatic adults without clinically apparent lung disease.This was a cross-sectional study of 240,562 Korean adults without known lung disease. All subjects underwent both pulmonary function test (PFT) and bioelectrical impedanc

Pulmonary and Respiratory MedicineMedicine
2
Article|48 citations·2021
Strong association of type 2 diabetes with degenerative lumbar spine disorders
Chul-Hyun Park, Kyoung‐Bok Min, Jin‐Young Min, Du Hwan Kim, Kyung Mook Seo, Don‐Kyu Kim, Don‐Kyu Kim, Don‐Kyu Kim
SJR Q1Scientific ReportsOA

Tantalizing connections between type 2 diabetes and degenerative lumbar spine disorders have become increasingly evident. However, the association of type 2 diabetes with degenerative lumbar spine disorders remains unclear. We sought to clarify the association between type 2 diabetes and lumbar spine disorders using nationwide data in Korea. Furthermore, we explored the association of diabetes with the prevalence of spinal procedures. The data in this study was obtained from Korean health claim

Pathology and Forensic MedicineMedicine
3
Article|41 citations·2018
Sarcopenic obesity associated with high-sensitivity C-reactive protein in age and sex comparison: a two-center study in South Korea
Chul‐Hyun Park, Jong Geol, Yong‐Taek Lee, Kyung Jae Yoon
SJR Q1BMJ OpenOA

OBJECTIVES: To evaluate the association between high-sensitivity C-reactive protein (hs-CRP) and sarcopenic obesity, and to determine age or sex differences underlying the relationship between hs-CRP and sarcopenic obesity. DESIGN: Observational study. PARTICIPANTS: The study included 237 838 participants whose body composition and hs-CRP were analysed at the two health promotion centres in South Korea. Participants were divided into four groups based on body composition: normal, obesity only, s

PhysiologyMedicine
4
Article|26 citations·2017
Ability of High-Resolution Manometry to Determine Feeding Method and to Predict Aspiration Pneumonia in Patients With Dysphagia
Chul‐Hyun Park, Yong‐Taek Lee, Youbin Yi, Jung-Sang Lee, Jung Ho Park, Kyung Jae Yoon
SJR Q1The American Journal of Gastroenterology

We first established the optimal thresholds for HRM parameters to determine feeding method and predict the development of aspiration pneumonia in patients with oropharyngeal dysphagia.

Speech and HearingHealth Professions
5
Article|24 citations·2022
Sex-Specific Associations between Serum Ferritin and Osteosarcopenic Obesity in Adults Aged over 50 Years
Sung-Joon Chung, Han-Sol Lim, Mi Yeon Lee, Yong‐Taek Lee, Kyung Jae Yoon, Chul‐Hyun Park
SJR Q1NutrientsOA

We investigated the sex-specific association between ferritin and adverse body composition in adults aged over 50 years in a population-based cohort. A total of 25,546 participants (16,912 women; 8634 men) were stratified into three groups by the tertiles of ferritin. The number of adverse body compositions was categorized as 0 (without osteopenia/osteoporosis, low muscle mass, or obesity), 1 (having one of the components), 2 (two), and 3 (all three; osteosarcopenic obesity). As ferritin tertile

HematologyMedicine
6
Article|22 citations·2017
Quantitative Analysis of Swallowing Function Between Dysphagia Patients and Healthy Subjects Using High-Resolution Manometry
Chul‐Hyun Park, Don‐Kyu Kim, Yong‐Taek Lee, Youbin Yi, Jung-Sang Lee, Kun-Woo Kim, Jung Ho Park, Kyung Jae Yoon
SJR Q1Annals of Rehabilitation MedicineOA

We present evidence that HRM could be a useful evaluation tool for detecting pharyngeal dysphagia.

Speech and HearingHealth Professions
7
Article|19 citations·2022
Sex Difference in Cutoff and Prevalence of Sarcopenia among 300,090 Urban Korean Population: Association with Metabolic Syndrome
Chul‐Hyun Park, Jong Geol, Yong‐Taek Lee, Kyung Jae Yoon
SJR Q2MedicinaOA

Background and Objectives: The study aimed to establish the threshold values and prevalence of sarcopenia and to investigate the association of sarcopenia with metabolic syndrome in an urban Korean population. Materials and Methods: The study included 300,090 adults who underwent anthropometric analyses by bioelectrical impedance analyzer. Sarcopenia was defined as: (1) class I, skeletal muscle mass index (SMI) within −1 to −2 standard deviations (SDs); (2) or class II, <−2 SD of SMI in a young

PhysiologyMedicine
8
Article|14 citations·2022
Association between osteosarcopenia and coronary artery calcification in asymptomatic individuals
Chul‐Hyun Park, Yong‐Taek Lee, Kyung Jae Yoon
SJR Q1Scientific ReportsOA

Abstract Osteoporosis and sarcopenia are substantially interrelated with shared cardiovascular risk factors. However, the relationship between osteosarcopenia and coronary artery disease is largely unexplored. We aimed to investigate the association between osteosarcopenia and coronary artery calcification (CAC) scores in asymptomatic adults. A total of 5969 asymptomatic adults without cardiovascular disease who underwent a health examination including estimation of CAC scores by cardiac tomogra

PhysiologyMedicine
9
Article|14 citations·2012
No negative symptoms in healthy volunteers after single doses of amisulpride, aripiprazole, and haloperidol
Chul‐Hyun Park, Tae‐Won Park, Jong-Chul Yang, Keon‐Hak Lee, Guang‐Biao Huang, Zhao Tong, Myung‐Sook Park, Young‐Chul Chung
SJR Q2International Clinical Psychopharmacology

Noncompliance and poor outcome in patients with schizophrenia are closely related to the negative symptoms secondary to antipsychotics. No controlled study has evaluated whether amisulpride and aripiprazole induce negative symptoms. The aim of this study was to assess the effects of single doses of amisulpride, aripiprazole, haloperidol, and risperidone in healthy volunteers. Seventy-eight young volunteers took part in this double-blind, randomized, placebo-controlled, parallel study of four ant

Psychiatry and Mental healthMedicine
10
Article|14 citations·2022
Relationship between hyperhomocysteinemia and coexisting obesity with low skeletal muscle mass in asymptomatic adult population
Tae Kyung Yoo, Hye Chang Rhim, Yong‐Taek Lee, Kyung Jae Yoon, Chul‐Hyun Park
SJR Q1Scientific ReportsOA

Abstract The relationship between hyperhomocysteinemia (HHcy) and obesity with low skeletal muscle mass (LMM) has not been established. We aim to assess the association between HHcy and the coexistence of obesity and LMM in asymptomatic adult population. We conducted a population-based cross-sectional study among asymptomatic individuals who underwent measurements of plasma homocysteine and body composition analysis. HHcy was defined as &gt; 15 umol/L, obesity as body mass index ≥ 25 (kg/m 2 ),

PhysiologyMedicine
11
Article|12 citations·2022
Increased Carcinoembryonic Antigen (CEA) Level Is Highly Associated with Low Skeletal Muscle Mass in Asymptomatic Adults: A Population-Based Study
Chul‐Hyun Park, Antonio Diaz Lizarraga, Yong‐Taek Lee, Kyung-Jae Yoon, Tae Kyung Yoo
SJR Q1Journal of Clinical MedicineOA

We investigated the relationship between high carcinoembryonic antigen (CEA) levels and low skeletal muscle mass (LMM) in asymptomatic adults in a population-based study. A total of 202,602 adults (mean age 41.7 years) without malignancy, stroke, cardiovascular disease, or chronic lung/liver disease were included. A high CEA level was defined as ≥5 ng/mL. Skeletal muscle mass index (SMI) was calculated based on appendicular muscle mass (kg)/height (m)2. Participants were classified into three gr

PhysiologyMedicine
12
Article|12 citations·2022
Impact of Low Skeletal Muscle Mass and Obesity on Hearing Loss in Asymptomatic Individuals: A Population-Based Study
Chul‐Hyun Park, Kyung Jae Yoon, Yong‐Taek Lee, Sung Min Jin, Sang Hyuk Lee, Tae Hwan Kim
SJR Q2HealthcareOA

The relationship between low muscle mass (LMM) with obesity and hearing loss has been poorly studied. We aimed to investigate the association of LMM and obesity on hearing loss in the general population. A total of 265,792 adults who underwent a hearing test and body composition analyses were included. Pre-sarcopenia was defined as having an appendicular muscle mass index <5.7 kg/m2 for women and <7.0 kg/m2 for men, and obesity as a body mass index ≥25 kg/m2, while pre-sarcopenic obesity was def

PhysiologyMedicine
13
Article|11 citations·2024
Long-term effects of lumbar flexion versus extension exercises for chronic axial low back pain: a randomized controlled trial
Chul‐Hyun Park, Jaewon Beom, Chun Kee Chung, Chi Heon Kim, Mi Yeon Lee, Myung Woo Park, Keewon Kim, Sun Gun Chung
SJR Q1Scientific ReportsOA

This study aimed to compare the long-term effects of flexion- and extension-based lumbar exercises on chronic axial low back pain (LBP). This was a 1-year follow-up of a prospective, assessor-blind, randomized controlled trial. Patients with axial LBP (intensity ≥ 5/10) for > 6 months allocated to the flexion or extension exercise group. Patients underwent four sessions of a supervised treatment program and were required to perform their assigned exercises daily at home. Clinical outcomes were o

PharmacologyMedicine
14
Article|8 citations·2023
Association of Pulmonary Function with Osteosarcopenic Obesity in Older Adults Aged over 50 Years
Han-Sol Lim, Dong‐Kun Kim, Hyun‐Il Gil, Mi Yeon Lee, Hyunseung Lee, Yong‐Taek Lee, Kyung Jae Yoon, Chul‐Hyun Park
SJR Q1NutrientsOA

Osteosarcopenic obesity (OSO) is a newly described coexistence of osteopenia/osteoporosis, sarcopenia, and obesity. We examined the association between pulmonary function, OSO, and its composition in adults aged ≥ 50 years. A total of 26,343 participants (8640 men; 17,703 women) were classified into four groups based on the number of abnormal body compositions (osteopenia/osteoporosis, sarcopenia, and obesity): 0 (control), 1+, 2+, and 3+ (OSO) abnormal body compositions. The values of forced vo

PhysiologyMedicine
15
Article|7 citations·2009
Internal Fixation of Proximal Humerus Fracture with Locking Compression Plate
Chul-Hyun Park, Sung-Hyuk Park, Jae-Sung Seo
SJR Q2Clinics in Shoulder and ElbowOA

We assessed the radiographic and clinical results of one surgeon's experience treating proximal humerus fractures with a locked proximal humeral plate. Materials and Methods: Twenty patients with unstable proximal humerus fractures were treated with a locking compression plate between February 2005 and September 2007. The average age of the patients was 60.6 years, and the average postoperative follow-up period was 22.3 months. The clinical results were evaluated using the Constant and DASH scor

SurgeryMedicine

Research Areas

PhysiologyPulmonary and Respiratory MedicineSurgerySpeech and HearingOrthopedics and Sports MedicineCardiology and Cardiovascular Medicine

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